The immunomodulatory effects of hypertonic saline resuscitation in patients sustaining traumatic hemorrhagic shock: a randomized, controlled, double-blinded trial (Q82053883)

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scientific article published on 01 January 2006

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English	The immunomodulatory effects of hypertonic saline resuscitation in patients sustaining traumatic hemorrhagic shock: a randomized, controlled, double-blinded trial	scientific article published on 01 January 2006

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scholarly article

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14 January 2020

The immunomodulatory effects of hypertonic saline resuscitation in patients sustaining traumatic hemorrhagic shock: a randomized, controlled, double-blinded trial (English)

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14 January 2020

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hemorrhagic shock

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author name string

Sandro B Rizoli

1

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14 January 2020

Shawn G Rhind

2

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14 January 2020

Pang N Shek

3

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14 January 2020

Kenji Inaba

4

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14 January 2020

Dennis Filips

5

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14 January 2020

Homer Tien

6

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14 January 2020

Fred Brenneman

7

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14 January 2020

Ori Rotstein

8

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14 January 2020

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1 January 2006

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14 January 2020

Annals of Surgery

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14 January 2020

243

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14 January 2020

1

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14 January 2020

47-57

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14 January 2020

Neuroendocrine responses mediate macrophage function after trauma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Immunomodulatory effects of hypertonic resuscitation on the development of lung inflammation following hemorrhagic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Cytokine signaling--regulation of the immune response in normal and critically ill states

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Definition of human blood monocytes

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https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Selective mobilization of CD14(+)CD16(+) monocytes by exercise

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Hypertonic inhibition of exocytosis in neutrophils: central role for osmotic actin skeleton remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Novel strategies for immunomodulation after trauma: revisiting hypertonic saline as a resuscitation strategy for hemorrhagic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Hypertonic saline infusion: can it regulate human neutrophil function?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Synergistic induction of IL-10 by hypertonic saline solution and lipopolysaccharides in murine peritoneal macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Adhesion molecules and hemorrhagic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Hypertonicity rescues T cells from suppression by trauma-induced anti-inflammatory mediators

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Role of monocyte L-selectin in the development of post-traumatic organ failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Hypertonic preconditioning inhibits macrophage responsiveness to endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Reduced rate of bacterial translocation and improved variables of natural killer cell and T-cell activity in rats surviving controlled hemorrhagic shock and treated with hypertonic saline

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Cytokine expression profiling in human leukocytes after exposure to hypertonic and isotonic fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Hypertonicity increases cAMP in PMN and blocks oxidative burst by PKA-dependent and -independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Small-volume resuscitation: from experimental evidence to clinical routine. Advantages and disadvantages of hypertonic solutions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Increased circulating CD16+ CD14dim monocytes in a patient with pulmonary alveolar proteinosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Pathogenesis of multiple organ dysfunction syndrome--endotoxin, inflammatory cells, and their mediators: cytokines and reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Cytokine flow cytometry: multiparametric approach to immune function analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Current concepts of the inflammatory response after major trauma: an update

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Hypertonic resuscitation: physiologic mechanisms and recommendations for trauma care

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Modeling the two-hit hypothesis for evaluating strategies to prevent organ injury after shock/resuscitation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Hypertonicity prevents lipopolysaccharide-stimulated CD11b/CD18 expression in human neutrophils in vitro: role for p38 inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Hypertonic immunomodulation is reversible and accompanied by changes in CD11b expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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CD14++ monocytes, CD14+/CD16+ subset and soluble CD14 as biological markers of inflammatory systemic diseases and monitoring immunosuppressive therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

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Immunomodulatory effects of vasoactive catecholamines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Blood monocytes consist of two principal subsets with distinct migratory properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Hypertonic resuscitation of hemorrhagic shock upregulates the anti-inflammatory response by alveolar macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Monocytes with altered phenotypes in posttrauma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Infusion of hypertonic saline (7.5% NaCl) causes minor immunological changes in normovolaemic women.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Prehospital Hypertonic Saline Resuscitation of Patients With Hypotension and Severe Traumatic Brain Injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Osmotic regulation of cell function and possible clinical applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Cytokines in patients with polytrauma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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The next generation in shock resuscitation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Immune effect of hypertonic saline: fact or fiction?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypertonic preconditioning prevents hepatocellular injury following ischemia/reperfusion in mice: a role for interleukin 10.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Hypertonic saline attenuates the hormonal response to injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Prehospital Hypertonic Saline/Dextran Infusion for Post-traumatic Hypotension The U.S.A. Multicenter Trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Neuroendocrine responses to hypertonic saline/dextran resuscitation following hemorrhage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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A review of the efficacy and safety of 7.5% NaCl/6% dextran 70 in experimental animals and in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential cytokine expression in human blood monocyte subpopulations: a polymerase chain reaction analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypertonic saline resuscitation decreases susceptibility to sepsis after hemorrhagic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Efficacy of hypertonic 7.5% saline and 6% dextran-70 in treating trauma: a meta-analysis of controlled clinical studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypertonic saline resuscitation: a tool to modulate immune function in trauma patients?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Tumor necrosis factor activity increases in the early response to trauma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trauma-induced alterations in macrophage function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

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Hypertonic saline resuscitation diminishes lung injury by suppressing neutrophil activation after hemorrhagic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of trauma and sepsis on soluble L-selectin and cell surface expression of L-selectin and CD11b

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A prospective, randomized, and controlled study of fluid management in children with severe head injury: lactated Ringer's solution versus hypertonic saline.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypertonic saline resuscitation reduces neutrophil margination by suppressing neutrophil L selectin expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human neutrophil activation and increased adhesion by various resuscitation fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/16371736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/01.SLA.0000193608.93127.B1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16371736%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16371736%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

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