Lens morphogenesis is dependent on Pax6-mediated inhibition of the canonical Wnt/beta-catenin signaling in the lens surface ectoderm (Q82311202)

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15 January 2020

title

Lens morphogenesis is dependent on Pax6-mediated inhibition of the canonical Wnt/beta-catenin signaling in the lens surface ectoderm (English)

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4

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author name string

Ondrej Machon

1

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15 January 2020

Jana Kreslova

2

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15 January 2020

Jana Ruzickova

3

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Lucie Klimova

5

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Naoko Fujimura

6

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Jitka Lachova

7

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Zbynek Kozmik

8

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publication date

1 February 2010

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volume

48

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issue

2

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page(s)

86-95

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Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development.

15 January 2020

cites work

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7 January 2021

Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye

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7 January 2021

Lens specification is the ground state of all sensory placodes, from which FGF promotes olfactory identity.

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7 January 2021

Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage

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7 January 2021

Forkhead Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation

1 reference

7 January 2021

Expression of Frizzleds and secreted frizzled-related proteins (Sfrps) during mammalian lens development.

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7 January 2021

Early eye development in vertebrates

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7 January 2021

Genetic dissection of Pax6 dosage requirements in the developing mouse eye

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7 January 2021

Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain

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7 January 2021

Prox1 is differentially localized during lens development

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7 January 2021

Pax6 is required for delta-catenin/neurojugin expression during retinal, cerebellar and cortical development in mice

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7 January 2021

Characterization of a transient TCF/LEF-responsive progenitor population in the embryonic mouse retina

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7 January 2021

BMP4 is essential for lens induction in the mouse embryo

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7 January 2021

The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development

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7 January 2021

Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina

1 reference

7 January 2021

Pax6: more than meets the eye.

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7 January 2021

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

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7 January 2021

Mouse small eye results from mutations in a paired-like homeobox-containing gene

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7 January 2021

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

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7 January 2021

Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity.

1 reference

7 January 2021

Pax-6 regulates expression of SFRP-2 and Wnt-7b in the developing CNS.

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7 January 2021

Pax genes in eye development and evolution

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7 January 2021

Abnormal lens morphogenesis and ectopic lens formation in the absence of beta-catenin function

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7 January 2021

Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina.

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7 January 2021

Mapping canonical Wnt signaling in the developing and adult retina

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7 January 2021

Growth factor regulation of lens development

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7 January 2021

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

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7 January 2021

A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus.

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7 January 2021

Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

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7 January 2021

Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.

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7 January 2021

Regulation of eye formation by the Rx and pax6 homeobox genes

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7 January 2021

The Rx homeobox gene is essential for vertebrate eye development

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7 January 2021

Vax genes ventralize the embryonic eye

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7 January 2021

The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm

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7 January 2021

Generalized lacZ expression with the ROSA26 Cre reporter strain

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7 January 2021

A role for Wnt/beta-catenin signaling in lens epithelial differentiation

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7 January 2021

Eye formation in the absence of retina.

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7 January 2021

BMP7 acts in murine lens placode development

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7 January 2021

Prox1 function is crucial for mouse lens-fibre elongation

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7 January 2021

A highly conserved lens transcriptional control element from the Pax-6 gene

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7 January 2021

Cell-autonomous involvement of Mab21l1 is essential for lens placode development

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7 January 2021

Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation

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7 January 2021

Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis

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7 January 2021

Identifiers

DOI

10.1002/DVG.20583

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15 January 2020

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