Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension (Q82459879)

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scientific article published on 01 January 2011

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English	Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension	scientific article published on 01 January 2011

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16 January 2020

Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension (English)

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16 January 2020

Soluble epoxide hydrolase

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16 January 2020

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Zuzana Honetschlägerová

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16 January 2020

Zuzana Husková

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16 January 2020

Zdeňka Vaňourková

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16 January 2020

Alexandra Sporková

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16 January 2020

Herbert J Kramer

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16 January 2020

Sung Hee Hwang

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16 January 2020

Hsing-Ju Tsai

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16 January 2020

Bruce D Hammock

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16 January 2020

Luděk Červenka

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16 January 2020

Libor Kopkan

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16 January 2020

publication date

1 January 2011

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16 January 2020

Journal of Physiology

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16 January 2020

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16 January 2020

Pt 1

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16 January 2020

207-219

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16 January 2020

In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecyl-urea.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome p450 and vascular homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-450 metabolites of arachidonic acid in the control of cardiovascular function

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Why are angiotensin concentrations so high in the kidney?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the formation of EETs and 20-HETE with 1-aminobenzotriazole attenuates pressure natriuresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood pressure and renal function during chronic changes in sodium intake: role of angiotensin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular signaling in the regulation of renal Na-K-ATPase. II. Role of eicosanoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paracrine regulation of the renal microcirculation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental studies demonstrate age-dependent elevation of renin activity in TGR(mRen2)27 rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of acute AT1 receptor blockade by candesartan on arterial pressure and renal function in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal cytochrome P450 omega-hydroxylase and epoxygenase activity are differentially modified by nitric oxide and sodium chloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arachidonic acid inhibits epithelial Na channel via cytochrome P450 (CYP) epoxygenase-dependent metabolic pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of intrarenal angiotensin II in the development of hypertension in Ren-2 transgenic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide contributes to development of salt sensitivity and hypertension induced by nitric oxide deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced tubuloglomerular feedback in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiovascular therapeutic aspects of soluble epoxide hydrolase inhibitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low Na intake suppresses expression of CYP2C23 and arachidonic acid-induced inhibition of ENaC

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AT1 receptor blockade is superior to conventional triple therapy in protecting against end-organ damage in Cyp1a1-Ren-2 transgenic rats with inducible hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic clamping of renin gene expression induces hypertension and elevation of intrarenal Ang II levels of graded severity in Cyp1a1-Ren2 transgenic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs).

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of endothelial nitric-oxide synthase activity through phosphorylation in response to epoxyeicosatrienoic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term prevention of hypertension and end-organ damage in Ren-2 transgenic rats is achieved only with persistent but not transient AT1 receptor blockade

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of hypertension in DOCA-salt rats by an inhibitor of soluble epoxide hydrolase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal vascular and tubulointerstitial inflammation and proliferation in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increasing or stabilizing renal epoxyeicosatrienoic acid production attenuates abnormal renal function and hypertension in obese rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of chronic cytochrome P-450 inhibition on the course of hypertension and end-organ damage in Ren-2 transgenic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orally bioavailable potent soluble epoxide hydrolase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of the cytochrome P450 arachidonic acid monooxygenases in the control of systemic blood pressure and experimental hypertension.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aldosterone receptor antagonism alleviates proteinuria, but not malignant hypertension, in Cyp1a1-Ren2 transgenic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between P450 eicosanoids and nitric oxide in the control of arterial tone in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reporting ethical matters in the Journal of Physiology: standards and advice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine2A receptors and epoxyeicosatrienoic acids: a recipe for salt and blood pressure regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1113/JPHYSIOL.2010.199505

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078594%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078594%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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