Mixed-model QSAR at the glucocorticoid receptor: predicting the binding mode and affinity of psychotropic drugs (Q82607614)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Mixed-model QSAR at the glucocorticoid receptor: predicting the binding mode and affinity of psychotropic drugs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Morena Spreafico

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Beat Ernst

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Markus A Lill

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Angelo Vedani

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

publication date

1 January 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

100-109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

Nuclear-receptor ligands and ligand-binding domains

17 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Steroid hormone receptors: many actors in search of a plot

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable?

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Efficacy and safety of inhaled corticosteroids. New developments

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Antiinflammatory action of glucocorticoids--new mechanisms for old drugs

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Multiple-conformation and protonation-state representation in 4D-QSAR: the neurokinin-1 receptor system.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

5D-QSAR: the key for simulating induced fit?

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Raptor: combining dual-shell representation, induced-fit simulation, and hydrophobicity scoring in receptor modeling: application toward the simulation of structurally diverse ligand sets

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Novel ligands for the chemokine receptor-3 (CCR3): a receptor-modeling study based on 5D-QSAR.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

VirtualToxLab - in silico prediction of the toxic potential of drugs and environmental chemicals: evaluation status and internet access protocol.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Glucocorticoid receptor interactions with glucocorticoids: evaluation by molecular modeling and functional analysis of glucocorticoid receptor mutants

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Synthesis and characterization of non-steroidal ligands for the glucocorticoid receptor: selective quinoline derivatives with prednisolone-equivalent functional activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Nonsteroidal selective glucocorticoid modulators: the effect of C-5 alkyl substitution on the transcriptional activation/repression profile of 2,5-dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Novel N-arylpyrazolo[3,2-c]-based ligands for the glucocorticoid receptor: receptor binding and in vivo activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Selective glucocorticoid receptor nonsteroidal ligands completely antagonize the dexamethasone mediated induction of enzymes involved in gluconeogenesis and glutamine metabolism.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Novel ketal ligands for the glucocorticoid receptor: in vitro and in vivo activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

The power issue: determination of KB or Ki from IC50. A closer look at the Cheng-Prusoff equation, the Schild plot and related power equations.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Class IV charge models: A new semiempirical approach in quantum chemistry

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Simulating alpha/beta selectivity at the human thyroid hormone receptor: consensus scoring using multidimensional QSAR

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Combining protein modeling and 6D-QSAR. Simulating the binding of structurally diverse ligands to the estrogen receptor.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Prediction of protein-ligand interactions. Docking and scoring: successes and gaps

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Effects of chronic alprazolam treatment on plasma concentrations of glucocorticoids, thyroid hormones, and testosterone in cardiomyopathic hamsters.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

The antidepressant clomipramine regulates cortisol intracellular concentrations and glucocorticoid receptor expression in fibroblasts and rat primary neurones

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Early life trauma decreases glucocorticoid receptors in rat dentate gyrus upon adult re-stress: reversal by escitalopram

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Differential regulation of variant glucocorticoid receptor mRNAs in the rat hippocampus by the antidepressant fluoxetine

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Partial glucocorticoid agonist-like effects of imipramine on hypothalamic-pituitary-adrenocortical activity, thymus weight, and hippocampal glucocorticoid receptors in male C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Acute reboxetine administration increases plasma and salivary cortisol

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Effect of sertraline on glucocorticoid sensitivity of mononuclear leukocytes in post-traumatic stress disorder

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Effects of methylphenidate and bupropion on DHEA-S and cortisol plasma levels in attention-deficit hyperactivity disorder

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

The effects of tricyclic antidepressants on breast cancer risk

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

General linearized biexponential model for QSAR data showing bilinear-type distribution

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Design and synthesis of new nonsteroidal glucocorticoid modulators through application of an "agreement docking" method

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Predicting the toxic potential of drugs and chemicals in silico: a model for the peroxisome proliferator-activated receptor gamma (PPAR gamma).

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800274

7 January 2021

Identifiers

DOI

10.1002/CMDC.200800274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19009570%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference