Landscape of TET2 mutations in acute myeloid leukemia (Q82675574)

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17 January 2020

title

Landscape of TET2 mutations in acute myeloid leukemia (English)

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17 January 2020

main subject

acute myeloid leukemia

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S Weissmann

1

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T Alpermann

2

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17 January 2020

V Grossmann

3

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17 January 2020

A Kowarsch

4

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N Nadarajah

5

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C Eder

6

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17 January 2020

F Dicker

7

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17 January 2020

A Fasan

8

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C Haferlach

9

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T Haferlach

10

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17 January 2020

W Kern

11

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S Schnittger

12

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A Kohlmann

13

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publication date

25 November 2011

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17 January 2020

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17 January 2020

volume

26

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17 January 2020

issue

5

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17 January 2020

page(s)

934-942

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Disruption of differentiation in human cancer: AML shows the way.

17 January 2020

cites work

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7 January 2021

Genetics of myeloid leukemias

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Acute myeloid leukemia

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Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications

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7 January 2021

Genomics and the continuum of cancer care

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7 January 2021

Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?

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7 January 2021

Molecular diagnostics in acute leukemias

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7 January 2021

IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status

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7 January 2021

RUNX1 mutations are frequent in de novo AML with noncomplex karyotype and confer an unfavorable prognosis

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7 January 2021

Mutation in TET2 in myeloid cancers

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7 January 2021

Acquired mutations in TET2 are common in myelodysplastic syndromes

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7 January 2021

TET2 mutations in myelodysplasia and myeloid malignancies

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7 January 2021

Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value

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7 January 2021

Novel TET2 mutations associated with UPD4q24 in myelodysplastic syndrome.

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7 January 2021

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

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7 January 2021

The Ph-positive and Ph-negative myeloproliferative neoplasms: some topical pre-clinical and clinical issues

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7 January 2021

TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs).

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7 January 2021

Incidence and prognostic value of TET2 alterations in de novo acute myeloid leukemia achieving complete remission.

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7 January 2021

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

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7 January 2021

TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study

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7 January 2021

Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials.

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7 January 2021

The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories.

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7 January 2021

R453Plus1Toolbox: an R/Bioconductor package for analyzing Roche 454 Sequencing data

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7 January 2021

Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype

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7 January 2021

Minimal residual disease levels assessed by NPM1 mutation-specific RQ-PCR provide important prognostic information in AML.

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7 January 2021

Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

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7 January 2021

Prognostic relevance of FLT3-TKD mutations in AML: the combination matters--an analysis of 3082 patients

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7 January 2021

Report on two novel nucleotide exchanges in the JAK2 pseudokinase domain: D620E and E627E

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7 January 2021

Comparison of chromosome banding analysis, interphase- and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic myeloid leukemia: a study on 350 cases.

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7 January 2021

A method and server for predicting damaging missense mutations

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7 January 2021

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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7 January 2021

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

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7 January 2021

Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

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7 January 2021

TET2 mutations in secondary acute myeloid leukemias: a French retrospective study

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7 January 2021

Clinical effect of point mutations in myelodysplastic syndromes

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7 January 2021

TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis

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7 January 2021

TET2 mutations in childhood leukemia

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7 January 2021

TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

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7 January 2021

Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor

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7 January 2021

High frequency of RUNX1 biallelic alteration in acute myeloid leukemia secondary to familial platelet disorder.

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7 January 2021

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

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7 January 2021

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

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7 January 2021