Targeting apoptosis: selected anticancer strategies (Q82771838)

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17 January 2020

title

Targeting apoptosis: selected anticancer strategies (English)

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17 January 2020

author name string

Shane Storey

series ordinal

1

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17 January 2020

publication date

1 December 2008

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Nature Reviews Drug Discovery

17 January 2020

published in

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17 January 2020

volume

7

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17 January 2020

issue

12

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17 January 2020

page(s)

971-972

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Functional genomics identifies ABCC3 as a mediator of taxane resistance in HER2-amplified breast cancer

17 January 2020

cites work

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Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma

31 March 2020

1 reference

Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).

31 March 2020

1 reference

Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy?

31 March 2020

1 reference

Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.

31 March 2020

1 reference

To kill a tumor cell: the potential of proapoptotic receptor agonists

31 March 2020

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Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the TRAIL receptor-1, in patients with advanced non-small cell lung cancer

31 March 2020

1 reference

Phase 1 and Pharmacokinetic Study of Lexatumumab in Patients with Advanced Cancers

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRD2662

1 reference

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17 January 2020

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