The vitamin D(3) receptor in the context of the nuclear receptor superfamily : The central role of the retinoid X receptor (Q82863470)

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18 January 2020

title

The vitamin D(3) receptor in the context of the nuclear receptor superfamily : The central role of the retinoid X receptor (English)

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18 January 2020

1

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18 January 2020

publication date

1 April 1996

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18 January 2020

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18 January 2020

volume

4

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18 January 2020

issue

2

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18 January 2020

page(s)

91-105

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The C-terminal region of the vitamin D receptor is essential to form a complex with a receptor auxiliary factor required for high affinity binding to the vitamin D-responsive element

18 January 2020

cites work

1 reference

12 December 2020

Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product

1 reference

12 December 2020

RXR-independent action of the receptors for thyroid hormone, retinoid acid and vitamin D on inverted palindromes

1 reference

12 December 2020

Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene

1 reference

12 December 2020

1,25-dihydroxyvitamin D-responsive element and glucocorticoid repression in the osteocalcin gene

1 reference

12 December 2020

Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently

1 reference

12 December 2020

A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit

1 reference

12 December 2020

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids

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12 December 2020

Identification of nuclear receptor mRNAs by RT-PCR amplification of conserved zinc-finger motif sequences

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12 December 2020

Identification of the porcine intestinal accessory factor that enables DNA sequence recognition by vitamin D receptor

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12 December 2020

FTZ-F1, a Steroid Hormone Receptor-like Protein Implicated in the Activation of fushi tarazu

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12 December 2020

RZRs, a new family of retinoid-related orphan receptors that function as both monomers and homodimers

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12 December 2020

Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors

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12 December 2020

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

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12 December 2020

1,25(OH)2-vitamin D3, a steroid hormone that produces biologic effects via both genomic and nongenomic pathways

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12 December 2020

The chicken progesterone receptor: sequence, expression and functional analysis

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12 December 2020

On the mechanism of DNA binding by nuclear hormone receptors: a structural and functional perspective

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12 December 2020

A nuclear factor that enhances binding of thyroid hormone receptors to thyroid hormone response elements.

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12 December 2020

Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene.

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12 December 2020

Anatomy of the Steroid Receptor Zinc Finger Region

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12 December 2020

RXR alpha, a promiscuous partner of retinoic acid and thyroid hormone receptors

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12 December 2020

A 55-kilodalton accessory factor facilitates vitamin D receptor DNA binding

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12 December 2020

A human retinoic acid receptor which belongs to the family of nuclear receptors

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12 December 2020

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

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12 December 2020

Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene

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12 December 2020

Determinants for selective RAR and TR recognition of direct repeat HREs.

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12 December 2020

Primary structure and expression of a functional human glucocorticoid receptor cDNA

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12 December 2020

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

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12 December 2020

Nonnuclear effects of the steroid hormone 1 alpha,25(OH)2-vitamin D3: analogs are able to functionally differentiate between nuclear and membrane receptors

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12 December 2020

Functional domains of the human estrogen receptor

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12 December 2020

Unique Biosynthesis by Kidney of a Biologically Active Vitamin D Metabolite

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12 December 2020

Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor

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12 December 2020

Molecular cloning of complementary DNA encoding the avian receptor for vitamin D.

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12 December 2020

Two amino acids within the knuckle of the first zinc finger specify DNA response element activation by the glucocorticoid receptor

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12 December 2020

Isomerization of all-trans-retinoids to 11-cis-retinoids in vitro

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12 December 2020

The steroid and thyroid hormone receptor superfamily

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12 December 2020

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12 December 2020

Vitamin D3-thyroid hormone receptor heterodimer polarity directs ligand sensitivity of transactivation

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12 December 2020

High affinity and specificity of dimeric binding of thyroid hormone receptors to DNA and their ligand-dependent dissociation

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12 December 2020

Mutations that alter ligand-induced switches and dimerization activities in the retinoid X receptor

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12 December 2020

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

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12 December 2020

Thyroid hormone receptors: multiple forms, multiple possibilities

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12 December 2020

Determinants of target gene specificity for steroid/thyroid hormone receptors

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12 December 2020

9-cis-retinoic acid is a natural antagonist for the retinoic acid receptor response pathway

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12 December 2020

The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains.

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12 December 2020

Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor

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12 December 2020

Identification of a vitamin D receptor homodimer-type response element in the rat calcitriol 24-hydroxylase gene promoter.

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12 December 2020

1,25-Dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cell line (HL-60): receptor-mediated maturation to macrophage-like cells

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12 December 2020

H-2RIIBP, a member of the nuclear hormone receptor superfamily that binds to both the regulatory element of major histocompatibility class I genes and the estrogen response element

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12 December 2020

RXR-dependent and RXR-independent transactivation by retinoic acid receptors

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12 December 2020

Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its E region

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12 December 2020

A nuclear hormone receptor-associated protein that inhibits transactivation by the thyroid hormone and retinoic acid receptors

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12 December 2020

Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.

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12 December 2020

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

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12 December 2020

Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements

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12 December 2020

RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

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12 December 2020

Identification of a receptor for the morphogen retinoic acid

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12 December 2020

Transcriptional regulation by the nuclear receptor superfamily

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12 December 2020

Two nuclear signalling pathways for vitamin D

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12 December 2020

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

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12 December 2020

Retinoic acid receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling

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12 December 2020

Participation of non-zinc finger residues in DNA binding by two nuclear orphan receptors

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12 December 2020

Specificity and flexibility of vitamin D signaling. Modulation of the activation of natural vitamin D response elements by thyroid hormone.

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12 December 2020

Orphan receptors: in search of a unifying hypothesis for activation

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12 December 2020

Cloning and expression of full-length cDNA encoding human vitamin D receptor

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12 December 2020

Nuclear receptors enhance our understanding of transcription regulation

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12 December 2020

Vitamin D receptor contains multiple dimerization interfaces that are functionally different

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12 December 2020

The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats.

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12 December 2020

The c-erb-A protein is a high-affinity receptor for thyroid hormone

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12 December 2020

Retinoid-X-receptor-alpha-independent binding of vitamin D receptor to its response element from human osteocalcin gene

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12 December 2020

The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat

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12 December 2020

A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements

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12 December 2020

Structure and regulation of the rat 1,25-dihydroxyvitamin D3 receptor

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12 December 2020

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

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12 December 2020

Retinoid X receptors stimulate and 9-cis retinoic acid inhibits 1,25-dihydroxyvitamin D3-activated expression of the rat osteocalcin gene

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12 December 2020

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12 December 2020

The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18

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12 December 2020

Structure of the retinoid X receptor alpha DNA binding domain: a helix required for homodimeric DNA binding

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12 December 2020

Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses

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12 December 2020

A tissue-specific enhancer confers Pit-1-dependent morphogen inducibility and autoregulation on the pit-1 gene.

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12 December 2020

Response element selectivity for heterodimerization of vitamin D receptors with retinoic acid and retinoid X receptors.

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12 December 2020

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

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12 December 2020

Thyroid hormone receptor functions as monomeric ligand-induced transcription factor on octameric half-sites. Consequences also for dimerization.

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12 December 2020

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

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12 December 2020

Retinoic acid and thyroid hormone induce gene expression through a common responsive element.

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12 December 2020

Nuclear receptor that identifies a novel retinoic acid response pathway

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12 December 2020

Chromosomal receptor for a vitamin D metabolite

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12 December 2020

Natural vitamin D3 response elements formed by inverted palindromes: polarity-directed ligand sensitivity of vitamin D3 receptor-retinoid X receptor heterodimer-mediated transactivation.

1 reference

12 December 2020

Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3.

1 reference

12 December 2020

Sequence and characterization of a coactivator for the steroid hormone receptor superfamily

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12 December 2020

Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors

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12 December 2020

LXR, a nuclear receptor that defines a distinct retinoid response pathway

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12 December 2020

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors

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12 December 2020

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1

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12 December 2020

Thyroid hormone alters the DNA binding properties of chicken thyroid hormone receptors alpha and beta

1 reference

12 December 2020

Exclusive Homodimerization of the Orphan Receptor Hepatocyte Nuclear Factor 4 Defines a New Subclass of Nuclear Receptors

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12 December 2020

Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3.

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12 December 2020

Structural determinants of nuclear receptor assembly on DNA direct repeats

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12 December 2020

Identification and characterization of a vitamin D3 response element of chicken carbonic anhydrase-II.

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12 December 2020

A transcriptional co-repressor that interacts with nuclear hormone receptors

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12 December 2020

Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor

1 reference

12 December 2020

Functional domains of the human glucocorticoid receptor

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12 December 2020

Oestrogen and glucocorticoid responsive elements are closely related but distinct

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12 December 2020

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

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12 December 2020

Nuclear receptors. Lonesome orphans

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12 December 2020

COUP orphan receptors are negative regulators of retinoic acid response pathways

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12 December 2020

Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element

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12 December 2020

Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors

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12 December 2020

DNA target selectivity by the vitamin D3 receptor: mechanism of dimer binding to an asymmetric repeat element

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12 December 2020

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

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12 December 2020

A nuclear protein essential for binding of rat 1,25-dihydroxyvitamin D3 receptor to its response elements

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12 December 2020

Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding

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12 December 2020

COUP transcription factor is a member of the steroid receptor superfamily

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12 December 2020

Newly identified actions of the vitamin D endocrine system

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12 December 2020

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

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12 December 2020

Thyroid hormone receptor homodimers can function as ligand-sensitive repressors

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12 December 2020

Activation of mammalian retinoid X receptors by the insect growth regulator methoprene

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12 December 2020

Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction

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12 December 2020

Vitamin D3 receptors: structure and function in transcription

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12 December 2020

Structure-function relationships in the vitamin D endocrine system

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12 December 2020

Ligand modulates the conversion of DNA-bound vitamin D3 receptor (VDR) homodimers into VDR-retinoid X receptor heterodimers

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12 December 2020

OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor

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12 December 2020

Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activity

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12 December 2020

Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling

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12 December 2020

A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily

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12 December 2020

Formation of retinoid X receptor homodimers leads to repression of T3 response: hormonal cross talk by ligand-induced squelching

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12 December 2020

Unliganded T3R, but not its oncogenic variant, v-erbA, suppresses RAR-dependent transactivation by titrating out RXR.

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12 December 2020

Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers

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12 December 2020

The 1,25-dihydroxyvitamin D3 (VD) analogues MC903, EB1089 and KH1060 activate the VD receptor: homodimers show higher ligand sensitivity than heterodimers with retinoid X receptors

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12 December 2020

Repression by ARP-1 Sensitizes Apolipoprotein A1 Gene Responsiveness to RXRα and Retinoic Acid

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12 December 2020

A dialogue on analogues Newer vitamin-D drugs for use in bone disease, psoriasis, and cancer

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12 December 2020

A conserved C-terminal sequence that is deleted in v-ErbA is essential for the biological activities of c-ErbA (the thyroid hormone receptor).

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12 December 2020

A novel nuclear receptor superfamily member in Xenopus that associates with RXR, and shares extensive sequence similarity to the mammalian vitamin D3 receptor

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12 December 2020

Mechanisms of nuclear signalling by vitamin D3. Interplay with retinoid and thyroid hormone signalling

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12 December 2020

Transcriptional mechanisms in anterior pituitary cell differentiation

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12 December 2020

Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA.

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12 December 2020

Vertebrate receptors: molecular biology, dimerization and response elements

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12 December 2020

Identification of a nuclear receptor that is activated by farnesol metabolites

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12 December 2020

Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity

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12 December 2020

Ordered binding of retinoic acid and retinoid-X receptors to asymmetric response elements involves determinants adjacent to the DNA-binding domain.

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12 December 2020

Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor

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12 December 2020

Evolution of the nuclear receptor gene superfamily

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12 December 2020

Identification of nuclear factors that enhance binding of the thyroid hormone receptor to a thyroid hormone response element

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12 December 2020

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid

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12 December 2020

The steroid receptor superfamily: more excitement predicted for the future

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12 December 2020

Thyroid hormone and retinoic acid receptors form heterodimers with retinoid X receptors on direct repeats, palindromes, and inverted palindromes

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12 December 2020

The anti-proliferative effect of vitamin D3 analogues is not mediated by inhibition of the AP-1 pathway, but may be related to promoter selectivity.

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12 December 2020

Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors

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12 December 2020

Interactions among a subfamily of nuclear hormone receptors: the regulatory zipper model

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12 December 2020

Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus

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12 December 2020

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

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12 December 2020

Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system

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12 December 2020

H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes

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12 December 2020

Steroid Hormones: Membrane transporters of steroid hormones

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12 December 2020

Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation

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12 December 2020

The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements

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12 December 2020

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

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12 December 2020

Identifiers

DOI

10.1007/BF02782754

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21153264%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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