Transcription factor Pax5 (BSAP) transactivates the RAG-mediated V(H)-to-DJ(H) rearrangement of immunoglobulin genes (Q83299250)

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20 January 2020

title

Transcription factor Pax5 (BSAP) transactivates the RAG-mediated V(H)-to-DJ(H) rearrangement of immunoglobulin genes (English)

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8

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author name string

Zhixin Zhang

1

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20 January 2020

Celia R Espinoza

2

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20 January 2020

Zhihong Yu

3

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20 January 2020

Robert Stephan

4

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20 January 2020

Ti He

5

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G Stuart Williams

6

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Peter D Burrows

7

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Ann J Feeney

9

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Max D Cooper

10

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publication date

7 May 2006

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20 January 2020

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volume

7

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issue

6

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page(s)

616-624

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Somatic generation of antibody diversity

20 January 2020

cites work

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7 January 2021

Clonal selection and learning in the antibody system

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7 January 2021

The mechanism and regulation of chromosomal V(D)J recombination

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7 January 2021

The V(D)J recombination activating gene, RAG-1.

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7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

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7 January 2021

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

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7 January 2021

V(D)J recombination: RAG proteins, repair factors, and regulation

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7 January 2021

Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow

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7 January 2021

Thymocyte Expression of RAG-1 and RAG-2: Termination by T Cell Receptor Cross-Linking

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7 January 2021

Down-regulation of RAG1 and RAG2 gene expression in PreB cells after functional immunoglobulin heavy chain rearrangement

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7 January 2021

Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

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7 January 2021

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

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7 January 2021

Recombination between immunoglobulin variable region gene segments is enhanced by transcription

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7 January 2021

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

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7 January 2021

Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro

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7 January 2021

Unequal access: regulating V(D)J recombination through chromatin remodeling

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7 January 2021

Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1.

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7 January 2021

Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase

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7 January 2021

Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA

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7 January 2021

A role for histone acetylation in the developmental regulation of VDJ recombination.

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7 January 2021

Evidence that murine pre-B cells synthesise μ heavy chains but no light chains

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7 January 2021

Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes

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7 January 2021

Expression of surrogate light chain receptors is restricted to a late stage in pre-B cell differentiation

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7 January 2021

The expression of Vpre-B/lambda 5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice

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7 January 2021

Transcriptional control of B-cell development

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7 January 2021

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

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7 January 2021

The helix-loop-helix gene E2A is required for B cell formation

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7 January 2021

Failure of B-cell differentiation in mice lacking the transcription factor EBF.

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7 January 2021

E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells

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7 January 2021

Induction of a diverse T cell receptor gamma/delta repertoire by the helix-loop-helix proteins E2A and HEB in nonlymphoid cells

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7 January 2021

Localized gene-specific induction of accessibility to V(D)J recombination induced by E2A and early B cell factor in nonlymphoid cells

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7 January 2021

DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.

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7 January 2021

DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5).

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7 January 2021

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

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7 January 2021

Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments

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7 January 2021

Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene

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7 January 2021

Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

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7 January 2021

Pax5 activates immunoglobulin heavy chain V to DJ rearrangement in transgenic thymocytes

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7 January 2021

Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells

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7 January 2021

V(D)J recombinatorial repertoire diversification during intraclonal pro-B to B-cell differentiation

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7 January 2021

Contribution of Vh gene replacement to the primary B cell repertoire

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7 January 2021

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

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7 January 2021

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

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7 January 2021

Individual V(H) promoters vary in strength, but the frequency of rearrangement of those V(H) genes does not correlate with promoter strength nor enhancer-independence

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7 January 2021

Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter

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7 January 2021

Structural studies of Ets-1/Pax5 complex formation on DNA

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7 January 2021

Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

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7 January 2021

The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells

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7 January 2021

Requirements for selective recruitment of Ets proteins and activation of mb-1/Ig-alpha gene transcription by Pax-5 (BSAP).

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7 January 2021

Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints

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7 January 2021

Identifiers

DOI

10.1038/NI1339

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20 January 2020

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