The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu (Q83356122)

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scientific article published on 02 May 2006

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English	The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu	scientific article published on 02 May 2006

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scholarly article

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21 January 2020

The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu (English)

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Mohamed L. Salem

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Sabry A El-Naggar

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Andre Kadima

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William E Gillanders

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David J Cole

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2 May 2006

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5119-5132

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21 January 2020

Innate immunity: impact on the adaptive immune response

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Toll-like receptors: critical proteins linking innate and acquired immunity

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling

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Protein kinase R regulates double-stranded RNA induction of TNF-alpha but not IL-1 beta mRNA in human epithelial cells

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Shaping of adaptive immune responses to soluble proteins by TLR agonists: a role for IFN-alpha/beta

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Polyriboinosinic polyribocytidylic acid [poly(I:C)]/TLR3 signaling allows class I processing of exogenous protein and induction of HIV-specific CD8+ cytotoxic T lymphocytes

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IL-15R alpha expression on CD8+ T cells is dispensable for T cell memory

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Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN

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Noncoding RNA danger motifs bridge innate and adaptive immunity and are potent adjuvants for vaccination

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Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity.

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Cytokines as a link between innate and adaptive antitumor immunity.

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Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection

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Microbial Compounds Selectively Induce Th1 Cell-Promoting or Th2 Cell-Promoting Dendritic Cells In Vitro with Diverse Th Cell-Polarizing Signals

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Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways.

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7 January 2021

Viral infection switches non-plasmacytoid dendritic cells into high interferon producers.

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CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism

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7 January 2021

Poly I:C prevents T cell-mediated hepatitis via an NK-dependent mechanism

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Involvement of natural killer cells in PolyI:C-induced liver injury

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IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells

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CD8(+) T cell responses: it's all downhill after their prime

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Apoptosis: an overview of the process and its relevance in disease.

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Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B

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The roles of IL-12 in providing a third signal for clonal expansion of naive CD8 T cells

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The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result from the rapid and prolonged activation of antigen-specific CD8+ T cells in vivo

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Systemic administration of IL-15 augments the antigen-specific primary CD8+ T cell response following vaccination with peptide-pulsed dendritic cells.

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Paracrine release of IL-12 stimulates IFN-gamma production and dramatically enhances the antigen-specific T cell response after vaccination with a novel peptide-based cancer vaccine

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The poststimulation program of CD4 versus CD8 T cells (death versus activation-induced nonresponsiveness).

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NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells

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Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation

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Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN-alpha beta and IFN-gamma.

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The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions.

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Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

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APC-independent activation of NK cells by the Toll-like receptor 3 agonist double-stranded RNA

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Identifiers

10.1016/J.VACCINE.2006.04.010

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21 January 2020

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Europe PubMed Central

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21 January 2020

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