Recent developments in the structure, function and regulation of platelet-derived growth factor and its receptors (Q83497510)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22358873%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Recent developments in the structure, function and regulation of platelet-derived growth factor and its receptors (English)

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23 January 2020

author name string

J Tiesman

series ordinal

1

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23 January 2020

A Rizzino

series ordinal

2

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23 January 2020

publication date

1 December 1989

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23 January 2020

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23 January 2020

volume

2

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23 January 2020

issue

4

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23 January 2020

page(s)

333-350

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Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor

23 January 2020

cites work

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12 December 2020

The alternatively spliced exon of the platelet-derived growth factor A chain encodes a nuclear targeting signal

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12 December 2020

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

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12 December 2020

Developmental expression of PDGF, TGF-alpha, and TGF-beta genes in preimplantation mouse embryos

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12 December 2020

A comparison of the platelet-derived growth factor-dependent tyrosine kinase activity in sparse and confluent fibroblasts

1 reference

12 December 2020

Platelet-Derived Growth Factor A Chain Is Maternally Encoded in Xenopus Embryos

1 reference

12 December 2020

In vitro mutagenesis of the v-sis transforming gene defines functional domains of its growth factor-related product

1 reference

12 December 2020

Identification of NGF receptor in chromatin of melanoma cells using monoclonal antibody to cell surface NGF receptor

1 reference

12 December 2020

Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors

1 reference

12 December 2020

Dimerization of B-type platelet-derived growth factor receptors occurs after ligand binding and is closely associated with receptor kinase activation

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12 December 2020

Comparison of biological properties and transforming potential of human PDGF-A and PDGF-B chains

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12 December 2020

Platelets as a source of fibroblast growth-promoting activity.

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12 December 2020

Signal transduction by the platelet-derived growth factor receptor

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12 December 2020

Two different subunits associate to create isoform-specific platelet-derived growth factor receptors

1 reference

12 December 2020

Induction and modulation of anchorage-independent growth by platelet-derived growth factor, fibroblast growth factor, and transforming growth factor-beta

1 reference

12 December 2020

Properties of the nerve growth factor receptor. Relationship between receptor structure and affinity

1 reference

12 December 2020

A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro

1 reference

12 December 2020

Tumor necrosis factor-induced expression of platelet-derived growth factor A-chain messenger RNA in fibroblasts

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12 December 2020

Differential regulation of expression of two platelet-derived growth factor receptor subunits by transforming growth factor-beta

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12 December 2020

Regulated expression of the platelet-derived growth factor A chain gene in microvascular endothelial cells

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12 December 2020

Transcriptional regulation of the A and B chain genes of platelet-derived growth factor in microvascular endothelial cells.

1 reference

12 December 2020

Fibroblast Growth Factor Messenger Ribonucleic Acid Expression in a Human Astrocytoma Cell Line: Regulation by Serum and Cell Density

1 reference

12 December 2020

Roles of calcium, serum, plasma, and folic acid in the control of proliferation of normal and Rous sarcoma virus-infected chicken fibroblasts

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12 December 2020

Processing of the platelet-derived growth factor receptor. Biosynthetic and degradation studies using anti-receptor antibodies

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12 December 2020

Expression and developmental control of platelet-derived growth factor A-chain and B-chain/Sis genes in rat aortic smooth muscle cells

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12 December 2020

Regulatory effects of cell density on the binding of transforming growth factor beta, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor

1 reference

12 December 2020

Chromatin binding of epidermal growth factor, nerve growth factor, and platelet-derived growth factor in cells bearing the appropriate surface receptors

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12 December 2020

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1 reference

12 December 2020

Transforming growth factor (TGF beta) decreases the proliferation of human bone marrow fibroblasts by inhibiting the platelet-derived growth factor (PDGF) binding

1 reference

12 December 2020

The 5' untranslated sequence of the c-sis/platelet-derived growth factor 2 transcript is a potent translational inhibitor

1 reference

12 December 2020

Two classes of PDGF receptor recognize different isoforms of PDGF

1 reference

12 December 2020

Partially transformed, anchorage-independent human diploid fibroblasts result from overexpression of the c-sis oncogene: mitogenic activity of an apparent monomeric platelet-derived growth factor 2 species

1 reference

12 December 2020

Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents

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12 December 2020

Identification of nonessential disulfide bonds and altered conformations in the v-sis protein, a homolog of the B chain of platelet-derived growth factor

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12 December 2020

Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types

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12 December 2020

Differentially regulated production of platelet-derived growth factor and of transforming growth factor beta by a human teratocarcinoma cell line.

1 reference

12 December 2020

Role of tyrosine kinase and membrane-spanning domains in signal transduction by the platelet-derived growth factor receptor

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12 December 2020

Chromosomal localization of the human homolog (c-sis) of the simian sarcoma virus onc gene

1 reference

12 December 2020

Structure and sequence of the human c-sis/platelet-derived growth factor 2 (SIS/PDGF2) transcriptional unit

1 reference

12 December 2020

Production of growth factors related to fibroblast growth factor and platelet-derived growth factor by human embryonal carcinoma cells

1 reference

12 December 2020

Density-dependent regulation of growth of BSC-1 cells in cell culture: control of growth by serum factors

1 reference

12 December 2020

Production and utilization of growth factors related to fibroblast growth factor by embryonal carcinoma cells and their differentiated cells

1 reference

12 December 2020

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

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12 December 2020

Calcium as a regulator of the proliferation of normal, but not of transformed, chicken fibroblasts in a plasma-containing medium

1 reference

12 December 2020

Identification of a signal for nuclear targeting in platelet-derived-growth-factor-related molecules

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12 December 2020

Insulin-like growth factor-II receptors in cultured rat hepatocytes: regulation by cell density.

1 reference

12 December 2020

Purification and properties of an endothelial cell growth factor from human platelets

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12 December 2020

Deletions in the C-terminal coding region of the v-sis gene: dimerization is required for transformation

1 reference

12 December 2020

Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class

1 reference

12 December 2020

Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA.

1 reference

12 December 2020

Biosynthesis of the v-sis gene product: signal sequence cleavage, glycosylation, and proteolytic processing

1 reference

12 December 2020

Tumor-Promoting Phorbol Esters Inhibit Binding of Epidermal Growth Factor to Cellular Receptors

1 reference

12 December 2020

Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes

1 reference

12 December 2020

The insulin receptor. Structural basis for high affinity ligand binding

1 reference

12 December 2020

Platelet-derived growth factor production by human umbilical vein endothelial cells is regulated by basic fibroblast growth factor

1 reference

12 December 2020

Purification and properties of porcine platelet-derived growth factor

1 reference

12 December 2020

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity

1 reference

12 December 2020

Regulation of expression of the c-sis proto-oncogene

1 reference

12 December 2020

Synthesis of a PDGF-like growth factor in human glioma and sarcoma cells suggests the expression of the cellular homologue to the transforming protein of simian sarcoma virus

1 reference

12 December 2020

Cell density regulates the number of cell surface receptors for fibroblast growth factor

1 reference

12 December 2020

Induction of platelet-derived growth factor receptor expression in smooth muscle cells and fibroblasts upon tissue culturing.

1 reference

12 December 2020

Ultrastructural localization of a platelet-derived growth factor/v-sis-related protein(s) in cytoplasm and nucleus of simian sarcoma virus-transformed cells

1 reference

12 December 2020

Interleukin-2: inception, impact, and implications

1 reference

12 December 2020

Cultured human endothelial cells express platelet-derived growth factor A chain.

1 reference

12 December 2020

Regulation of production of a platelet-derived growth factor-like protein by cultured bovine aortic endothelial cells.

1 reference

12 December 2020

A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains

1 reference

12 December 2020

Platelet-derived growth factor. I. High yield purification and evidence for multiple forms.

1 reference

12 December 2020

Effects of Epidermal Growth Factor and 12-O-Tetradecanoylphorbol-13-Acetate on Metabolism of the Epidermal Growth Factor Receptor in Normal Human Fibroblasts

1 reference

12 December 2020

Influences of mRNA secondary structure on initiation by eukaryotic ribosomes

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12 December 2020

Ultrastructural localization of platelet-derived growth factor and related factors in normal and transformed cells

1 reference

12 December 2020

Deletions in the N-terminal coding region of the v-sis gene: determination of the minimal transforming region

1 reference

12 December 2020

Serum contains a platelet-derived transforming growth factor

1 reference

12 December 2020

Decreased binding of epidermal growth factor to BALB/c 3T3 mutant cells defective in glycoprotein synthesis

1 reference

12 December 2020

Platelet-derived growth factor A chain: gene structure, chromosomal location, and basis for alternative mRNA splicing

1 reference

12 December 2020

Effects of growth and insulin treatment on the levels of insulin receptors and their mRNA in Hep G2 cells.

1 reference

12 December 2020

Production of PDGF-like growth factors by embryonal carcinoma cells and binding of PDGF to their endoderm-like differentiated cells

1 reference

12 December 2020

Isolation of functional alpha beta heterodimers from the purified human placental alpha 2 beta 2 heterotetrameric insulin receptor complex. A structural basis for insulin binding heterogeneity

1 reference

12 December 2020

cDNA clones reveal differences between human glial and endothelial cell platelet-derived growth factor A-chains

1 reference

12 December 2020

Rat skeletal myoblasts and arterial smooth muscle cells express the gene for the A chain but not the gene for the B chain (c-sis) of platelet-derived growth factor (PDGF) and produce a PDGF-like protein

1 reference

12 December 2020

Evidence that autophosphorylation of solubilized receptors for epidermal growth factor is mediated by intermolecular cross-phosphorylation

1 reference

12 December 2020

Interferon-gamma modulates messenger RNA levels of c-sis (PDGF-B chain), PDGF-A chain, and IL-1 beta genes in human vascular endothelial cells

1 reference

12 December 2020

Human platelet-derived growth factor (PDGF): amino-terminal amino acid sequence

1 reference

12 December 2020

The role of individual cysteine residues in the structure and function of the v-sis gene product.

1 reference

12 December 2020

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules

1 reference

12 December 2020

A glioma-derived PDGF A chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets.

1 reference

12 December 2020

Human plasma epidermal growth factor/beta-urogastrone is associated with blood platelets

1 reference

12 December 2020

The platelet-derived growth factor

1 reference

12 December 2020

Nerve growth factor receptors: identification of distinct classes in plasma membranes and nuclei of embryonic dorsal root neurons

1 reference

12 December 2020

Structural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteins

1 reference

12 December 2020

Antibodies against platelet-derived growth factor inhibit acute transformation by simian sarcoma virus

1 reference

12 December 2020

Cultured primate aortic smooth muscle cells express both the PDGF-A and PDGF-B genes but do not secrete mitogenic activity or dimeric platelet-derived growth factor protein

1 reference

12 December 2020

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1 reference

12 December 2020

Platelet-derived growth factor receptors expressed by cDNA transfection couple to a diverse group of cellular responses associated with cell proliferation

1 reference

12 December 2020

Autocrine secretion and malignant transformation of cells.

1 reference

12 December 2020

Growth factors from murine sarcoma virus-transformed cells

1 reference

12 December 2020

Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation

1 reference

12 December 2020

Alternative RNA splicing affects function of encoded platelet-derived growth factor A chain

1 reference

12 December 2020

Identification and structural analysis of the A type receptor for platelet-derived growth factor. Similarities with the B type receptor.

1 reference

12 December 2020

Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects

1 reference

12 December 2020

Binding domains and epitopes in platelet-derived growth factor

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12 December 2020

Density-associated loss of functional receptors for somatomedin-C/insulinlike growth factor I (SM-C/IGF-I) on cultured human fibroblast monolayers

1 reference

12 December 2020

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

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12 December 2020

Human platelet-derived growth factor (PDGF): purification of PDGF-I and PDGF-II and separation of their reduced subunits

1 reference

12 December 2020

A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain.

1 reference

12 December 2020

Rapid turnover of the platelet-derived growth factor receptor in sis-transformed cells and reversal by suramin. Implications for the mechanism of autocrine transformation

1 reference

12 December 2020

A v-sis oncogene protein produced in bacteria competes for platelet-derived growth factor binding to its receptor

1 reference

12 December 2020