Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans. Part A: use of FDA post-market reports to create a database of hepatobiliary and urinary tract toxicities (Q83783482)

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scientific article published on 01 June 2009

Language	Label	Description	Also known as
English	Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans. Part A: use of FDA post-market reports to create a database of hepatobiliary and urinary tract toxicities	scientific article published on 01 June 2009

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scholarly article

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27 January 2020

Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans. Part A: use of FDA post-market reports to create a database of hepatobiliary and urinary tract toxicities (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19422096%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

author name string

Carling J Ursem

1

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27 January 2020

Naomi L Kruhlak

2

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27 January 2020

Joseph F Contrera

3

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27 January 2020

Philip M MacLaughlin

4

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27 January 2020

R Daniel Benz

5

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27 January 2020

Edwin J Matthews

6

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27 January 2020

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1 June 2009

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27 January 2020

Regulatory Toxicology and Pharmacology

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27 January 2020

54

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27 January 2020

1

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27 January 2020

1-22

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27 January 2020

Comparative performance of two quantitative safety signalling methods: implications for use in a pharmacovigilance department.

1 reference

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Toxicological and clinical computational analysis and the US FDA/CDER.

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Describing the validity of carcinogen screening tests

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Use of proportional reporting ratios (PRRs) for signal generation from spontaneous adverse drug reaction reports

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A gene expression signature that predicts the future onset of drug-induced renal tubular toxicity

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Evaluation of the Characteristics of Safety Withdrawal of Prescription Drugs from Worldwide Pharmaceutical Markets-1960 to 1999

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A new highly specific method for predicting the carcinogenic potential of pharmaceuticals in rodents using enhanced MCASE QSAR-ES software

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Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.

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Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans: Part B. Use of (Q)SAR systems for early detection of drug-induced hepatobiliary and urinary tract toxicities

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.12.009

7 January 2021

Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans: Part C: use of QSAR and an expert system for the estimation of the mechanism of action of drug-induced hepatobiliary and urinary tract toxicities

1 reference

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7 January 2021

Combined Use of MC4PC, MDL-QSAR, BioEpisteme, Leadscope PDM, and Derek for Windows Software to Achieve High-Performance, High-Confidence, Mode of Action-Based Predictions of Chemical Carcinogenesis in Rodents.

1 reference

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7 January 2021

The history of disproportionality measures (reporting odds ratio, proportional reporting rates) in spontaneous reporting of adverse drug reactions

1 reference

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7 January 2021

Drug-related hepatotoxicity

1 reference

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7 January 2021

Drug-induced renal failure: update on new medications and unique mechanisms of nephrotoxicity

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HIV-associated renal diseases and highly active antiretroviral therapy-induced nephropathy

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Nephrotoxic potential of selective cyclooxygenase-2 inhibitors

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Use of screening algorithms and computer systems to efficiently signal higher-than-expected combinations of drugs and events in the US FDA's spontaneous reports database

1 reference

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7 January 2021

Pharmacovigilance in the 21st century: new systematic tools for an old problem

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Identifiers

10.1016/J.YRTPH.2008.12.009

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19422096%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19422096%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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