Treatment with olaparib in a patient with PTEN-deficient endometrioid endometrial cancer (Q83787893)

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27 January 2020

title

Treatment with olaparib in a patient with PTEN-deficient endometrioid endometrial cancer (English)

1 reference

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27 January 2020

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3

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27 January 2020

author name string

Martin D Forster

1

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27 January 2020

Konstantin J Dedes

2

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27 January 2020

Sophia Frentzas

4

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27 January 2020

Rebecca Kristeleit

5

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27 January 2020

Alan Ashworth

6

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27 January 2020

Christopher J Poole

7

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Britta Weigelt

8

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Stan B Kaye

9

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L Rhoda Molife

10

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publication date

5 April 2011

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Nature Reviews Clinical Oncology

27 January 2020

published in

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volume

8

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27 January 2020

page(s)

302-306

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issue

5

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Hallmarks of 'BRCAness' in sporadic cancers

27 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

Tenets of PTEN tumor suppression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

A somatic BRCA2 mutation in RER+ endometrial carcinomas that specifically deletes the amino-terminal transactivation domain

31 March 2020

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A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair

31 March 2020

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

31 March 2020

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DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells

31 March 2020

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Targeting the double-strand DNA break repair pathway as a therapeutic strategy

31 March 2020

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Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

31 March 2020

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Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

Oncogenic mutations of PIK3CA in human cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

Molecular and pathologic aspects of endometrial carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

Essential role for nuclear PTEN in maintaining chromosomal integrity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.42

Posttranscriptional regulation of PTEN dosage by noncoding RNAs

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21468130

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21468130

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRCLINONC.2011.42

1 reference

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27 January 2020

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