Transdermal application of lovastatin to rats causes profound increases in bone formation and plasma concentrations (Q83940088)

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29 January 2020

title

Transdermal application of lovastatin to rats causes profound increases in bone formation and plasma concentrations (English)

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29 January 2020

author name string

G E Gutierrez

1

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29 January 2020

D Lalka

2

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29 January 2020

I R Garrett

3

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29 January 2020

G Rossini

4

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29 January 2020

G R Mundy

5

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publication date

3 May 2006

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Osteoporosis International

29 January 2020

published in

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volume

17

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issue

7

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29 January 2020

page(s)

1033-1042

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https://scigraph.springernature.com/pub.10.1007/s00198-006-0079-0

29 January 2020

exact match

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Biotransformation of lovastatin. IV. Identification of cytochrome P450 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes

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Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver

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Biotransformation of lovastatin. II. In vitro metabolism by rat and mouse liver microsomes and involvement of cytochrome P-450 in dehydrogenation of lovastatin

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Statin given perorally to adult rats increases cancellous bone mass and compressive strength

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10.1007/S00198-006-0079-0

Identifiers

DOI

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29 January 2020

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