Renal tubular PD-L1 (CD274) suppresses alloreactive human T-cell responses (Q84066700)

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31 January 2020

title

Renal tubular PD-L1 (CD274) suppresses alloreactive human T-cell responses (English)

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3

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author name string

Astrid Starke

1

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31 January 2020

Maja T Lindenmeyer

2

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31 January 2020

Matthias A Neusser

4

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31 January 2020

Barbara Rüsi

5

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31 January 2020

Daniel M Schmid

6

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31 January 2020

Clemens D Cohen

7

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31 January 2020

Rudolf P Wüthrich

8

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31 January 2020

Thomas Fehr

9

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31 January 2020

Ying Waeckerle-Men

10

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language of work or name

English

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publication date

14 April 2010

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31 January 2020

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31 January 2020

volume

78

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issue

1

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page(s)

38-47

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https://scigraph.springernature.com/pub.10.1038/ki.2010.97

31 January 2020

exact match

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PD-L2 is a second ligand for PD-1 and inhibits T cell activation

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Limited costimulatory molecule expression on renal tubular epithelial cells impairs T cell activation

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Renal tubular epithelial cells modulate T-cell responses via ICOS-L and B7-H1.

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Suppressed T-cell activation by IFN-gamma-induced expression of PD-L1 on renal tubular epithelial cells.

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PD-L1 partially protects renal tubular epithelial cells from the attack of CD8+ cytotoxic T cells

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Blockade of the interaction between PD-1 and PD-L1 accelerates graft arterial disease in cardiac allografts

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Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway

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PD-L1 is expressed by human renal tubular epithelial cells and suppresses T cell cytokine synthesis

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