Pharmacodynamic effects of cangrelor and clopidogrel: the platelet function substudy from the cangrelor versus standard therapy to achieve optimal management of platelet inhibition (CHAMPION) trials (Q84090833)

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scientific article published on 01 July 2012

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English	Pharmacodynamic effects of cangrelor and clopidogrel: the platelet function substudy from the cangrelor versus standard therapy to achieve optimal management of platelet inhibition (CHAMPION) trials	scientific article published on 01 July 2012

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scholarly article

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31 January 2020

Pharmacodynamic effects of cangrelor and clopidogrel: the platelet function substudy from the cangrelor versus standard therapy to achieve optimal management of platelet inhibition (CHAMPION) trials (English)

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31 January 2020

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pharmacodynamics

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Dominick Angiolillo

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object named as

Dominick J Angiolillo

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author name string

David J Schneider

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31 January 2020

Deepak L Bhatt

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William J French

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Matthew J Price

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Jorge F Saucedo

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31 January 2020

Tamaz Shaburishvili

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31 January 2020

Kurt Huber

8

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Jayne Prats

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Tiepu Liu

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Robert A Harrington

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Richard C Becker

12

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publication date

1 July 2012

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Journal of Thrombosis and Thrombolysis

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34

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44-55

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1

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https://scigraph.springernature.com/pub.10.1007/s11239-012-0737-3

0 references

Bridging antiplatelet therapy with cangrelor in patients undergoing cardiac surgery: a randomized controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

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Point-of-care measurement of clopidogrel responsiveness predicts clinical outcome in patients undergoing percutaneous coronary intervention results of the ARMYDA-PRO (Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty-Platele

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet aggregation and its association with stent thrombosis and bleeding in clopidogrel-treated patients: initial evidence of a therapeutic window

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous platelet blockade with cangrelor during PCI.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

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Cangrelor: a review on its mechanism of action and clinical development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

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A comparison of the VerifyNow P2Y12 point-of-care device and light transmission aggregometry to monitor platelet function with prasugrel and clopidogrel: an integrated analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

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Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

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Streamlining the design of promising clinical trials: in-vitro testing of antithrombotic regimens and multiple agonists of platelet activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

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Variability in individual responsiveness to clopidogrel: clinical implications, management, and future perspectives

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

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Usefulness of platelet response to clopidogrel by point-of-care testing to predict bleeding outcomes in patients undergoing percutaneous coronary intervention (from the Antiplatelet Therapy for Reduction of Myocardial Damage During Angioplasty-Bleed

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet inhibition with cangrelor in patients undergoing PCI.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transitioning patients from cangrelor to clopidogrel: pharmacodynamic evidence of a competitive effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventi

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet reactivity after clopidogrel treatment assessed with point-of-care analysis and early drug-eluting stent thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suboptimal early inhibition of platelets by treatment with tirofiban and implications for coronary interventions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ticagrelor versus clopidogrel in patients with acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

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The reversible P2Y antagonist cangrelor influences the ability of the active metabolites of clopidogrel and prasugrel to produce irreversible inhibition of platelet function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

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Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: a 12-month follow-up

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

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Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

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Platelet function testing and risk of bleeding complications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

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Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased concentrations of tirofiban in blood and their correlation with inhibition of platelet aggregation after greater bolus doses of tirofiban

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Ca2+ on GP IIb-IIIa interactions with integrilin: enhanced GP IIb-IIIa binding and inhibition of platelet aggregation by reductions in the concentration of ionized calcium in plasma anticoagulated with citrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of two platelet glycoprotein IIb/IIIa inhibitors, tirofiban and abciximab, for the prevention of ischemic events with percutaneous coronary revascularization

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced immediate ischemic events with cangrelor in PCI: a pooled analysis of the CHAMPION trials using the universal definition of myocardial infarction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prasugrel versus clopidogrel in patients with acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22569899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11239-012-0737-3

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Europe PubMed Central

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31 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22569899%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

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