Accelerated blood clearance phenomenon upon repeated injection of PEG-modified PLA-nanoparticles (Q84295405)

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3 February 2020

title

Accelerated blood clearance phenomenon upon repeated injection of PEG-modified PLA-nanoparticles (English)

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Tsutomu Ishihara

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Miho Takeda

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Haruka Sakamoto

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Ayumi Kimoto

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Chisa Kobayashi

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Naoko Takasaki

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Kanae Yuki

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Ken-ichiro Tanaka

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Mitsuko Takenaga

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Rie Igarashi

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Taishi Maeda

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Naoki Yamakawa

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Yoshinari Okamoto

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Masami Otsuka

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Tatsuhiro Ishida

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Hiroshi Kiwada

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Yutaka Mizushima

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Tohru Mizushima

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publication date

25 July 2009

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published in

Pharmaceutical Research

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volume

26

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issue

10

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page(s)

2270-2279

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Accelerated blood clearance and altered biodistribution of repeated injections of sterically stabilized liposomes

3 February 2020

cites work

1 reference

12 December 2020

Prostaglandin E1 and arterial occlusive disease: pharmacological considerations

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12 December 2020

Effect of eight prostaglandins on platelet aggregation

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12 December 2020

PEGylated liposomes elicit an anti-PEG IgM response in a T cell-independent manner

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12 December 2020

Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes

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Efficient encapsulation of a water-soluble corticosteroid in biodegradable nanoparticles

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Randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of AS-013, a prostaglandin E1 prodrug, in patients with intermittent claudication

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12 December 2020

Factors affecting the accelerated blood clearance of polyethylene glycol-liposomes upon repeated injection.

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Prostaglandins: Their Disappearance from and Release into the Circulation

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12 December 2020

Accelerated clearance of a second injection of PEGylated liposomes in mice

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Intravenous prostaglandin E1 in severe peripheral vascular disease

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12 December 2020

Influence of the physicochemical properties of liposomes on the accelerated blood clearance phenomenon in rats.

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12 December 2020

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12 December 2020

Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes

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Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

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12 December 2020

Surface modification of poly(lactide-co-glycolide) nanospheres by biodegradable poly(lactide)-poly(ethylene glycol) copolymers

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12 December 2020

Polyethylene glycol reactive antibodies in man: titer distribution in allergic patients treated with monomethoxy polyethylene glycol modified allergens or placebo, and in healthy blood donors

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12 December 2020

Particle size-dependent triggering of accelerated blood clearance phenomenon

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12 December 2020

Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes

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12 December 2020

PLA/PLGA nanoparticles for sustained release of docetaxel.

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12 December 2020

Kinetics of dehydration and isomerization of prostaglandins E 1 and E 2 .

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12 December 2020

Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes.

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12 December 2020

Stealth Me.PEG-PLA nanoparticles avoid uptake by the mononuclear phagocytes system

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12 December 2020

Polyethylene glycol-liposomal doxorubicin: a review of its use in the management of solid and haematological malignancies and AIDS-related Kaposi's sarcoma

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12 December 2020

The accelerated clearance on repeated injection of pegylated liposomes in rats: laboratory and histopathological study

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12 December 2020

Prolonging the in vivo residence time of prostaglandin E(1) with biodegradable nanoparticles

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12 December 2020

Accelerated blood clearance of PEGylated liposomes upon repeated injections: effect of doxorubicin-encapsulation and high-dose first injection

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12 December 2020

Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes

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12 December 2020

New preparation method for 9-anthryldiazomethane (ADAM) as a fluorescent labeling reagent for fatty acids and derivatives

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12 December 2020

Role of zinc in formulation of PLGA/PLA nanoparticles encapsulating betamethasone phosphate and its release profile

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12 December 2020

Prostaglandin E1 is more effective, when incorporated in lipid microspheres, for treatment of peripheral vascular diseases in man

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12 December 2020

Biodegradable long-circulating polymeric nanospheres

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12 December 2020

Ionically fixed polymeric nanoparticles as a novel drug carrier

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12 December 2020

The morbidity and mortality following a diagnosis of peripheral arterial disease: long-term follow-up of a large database

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12 December 2020

Accelerated clearance of PEGylated liposomes in rats after repeated injections

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12 December 2020

Brain delivery property and accelerated blood clearance of cationic albumin conjugated pegylated nanoparticle

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12 December 2020

The contribution of phagocytic activity of liver macrophages to the accelerated blood clearance (ABC) phenomenon of PEGylated liposomes in rats

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12 December 2020

10.1007/S11095-009-9943-X

Identifiers

DOI

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3 February 2020

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