Nasal and skin delivery of IC31(®)-adjuvanted recombinant HSV-2 gD protein confers protection against genital herpes (Q84340924)

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4 February 2020

title

Nasal and skin delivery of IC31(®)-adjuvanted recombinant HSV-2 gD protein confers protection against genital herpes (English)

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4 February 2020

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Benjamin Wizel

1

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4 February 2020

Josefine Persson

2

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4 February 2020

Karolina Thörn

3

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4 February 2020

Eszter Nagy

4

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4 February 2020

Ali M Harandi

5

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4 February 2020

publication date

1 June 2012

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4 February 2020

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4 February 2020

volume

30

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4 February 2020

issue

29

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4 February 2020

page(s)

4361-4368

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Herpes Simplex: Insights on Pathogenesis and Possible Vaccines

4 February 2020

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IC31, a novel adjuvant signaling via TLR9, induces potent cellular and humoral immune responses

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The novel adjuvant IC31 strongly improves influenza vaccine-specific cellular and humoral immune responses in young adult and aged mice.

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Intranasal immunization with CpG oligodeoxynucleotides as an adjuvant dramatically increases IgA and protection against herpes simplex virus-2 in the genital tract

7 January 2021

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Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital herpes

7 January 2021

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Intranasal immunization with a proteoliposome-derived cochleate containing recombinant gD protein confers protective immunity against genital herpes in mice

7 January 2021

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The mucosal adjuvant effect of alpha-galactosylceramide for induction of protective immunity to sexually transmitted viral infection

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7 January 2021

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Interferon-gamma enhances resolution of herpes simplex virus type 2 infection of the murine genital tract

7 January 2021

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Differential roles of B cells and IFN-gamma-secreting CD4(+) T cells in innate and adaptive immune control of genital herpes simplex virus type 2 infection in mice

7 January 2021

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Interleukin-12 (IL-12) and IL-18 are important in innate defense against genital herpes simplex virus type 2 infection in mice but are not required for the development of acquired gamma interferon-mediated protective immunity

7 January 2021

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The role of gamma interferon in immune resistance to vaginal infection by herpes simplex virus type 2 in mice

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Clearance of HSV-2 from recurrent genital lesions correlates with infiltration of HSV-specific cytotoxic T lymphocytes

7 January 2021

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Herpes simplex virus-2 (HSV-2) type-specific antibody correlates of protection in infants exposed to HSV-2 at birth

7 January 2021

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Antibody-mediated protection against genital herpes simplex virus type 2 disease in mice by Fc gamma receptor-dependent and -independent mechanisms

7 January 2021

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Protective immunity against HSV-2 in the mouse vagina

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VACCINE.2012.02.019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22682292%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference