CD4+CD25+ regulatory T cells suppress Th17-responses in an experimental colitis model (Q84348158)

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4 February 2020

title

CD4+CD25+ regulatory T cells suppress Th17-responses in an experimental colitis model (English)

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4 February 2020

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3

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4 February 2020

author name string

Haruei Ogino

1

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4 February 2020

Kazuhiko Nakamura

2

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4 February 2020

Hirotada Akiho

4

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4 February 2020

Ryoichi Takayanagi

5

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4 February 2020

publication date

3 June 2010

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Digestive Diseases and Sciences

4 February 2020

published in

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4 February 2020

volume

56

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4 February 2020

issue

2

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4 February 2020

page(s)

376-386

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IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

4 February 2020

cites work

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12 December 2020

Enhanced expression of iNOS in inflamed colons of IL-2-deficient mice does not impair colonic epithelial barrier function.

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T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

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T helper 1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis

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Preparation of functionally preserved CD4+ CD25high regulatory T cells from leukapheresis products from ulcerative colitis patients, applicable to regulatory T-cell transfer therapy

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Transforming growth factor beta induced FoxP3+ regulatory T cells suppress Th1 mediated experimental colitis.

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Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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The fundamental basis of inflammatory bowel disease

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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12 December 2020

The immunological and genetic basis of inflammatory bowel disease

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Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis

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12 December 2020

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

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12 December 2020

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

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Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

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Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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Microbial lipopeptides induce the production of IL-17 in Th cells.

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CD4+CD25+ Regulatory T Cells Cure Murine Colitis: The Role of IL-10, TGF-β, and CTLA4

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An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

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Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

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Monitoring of vaccine-specific gamma interferon induction in genital mucosa of mice by real-time reverse transcription-PCR.

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Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis

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Regulatory T cells: key controllers of immunologic self-tolerance

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12 December 2020

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

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12 December 2020

Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

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12 December 2020

A protective function for interleukin 17A in T cell-mediated intestinal inflammation

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12 December 2020

A new model of chronic colitis in SCID mice induced by adoptive transfer of CD62L+ CD4+ T cells: insights into the regulatory role of interleukin-6 on apoptosis

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12 December 2020

Transforming growth factor-beta induces development of the T(H)17 lineage

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12 December 2020

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

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12 December 2020

IL-23/IL-17 immunity as a hallmark of Crohn's disease

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12 December 2020

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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12 December 2020

CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice

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12 December 2020

IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease

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12 December 2020

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

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12 December 2020

TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

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12 December 2020

RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.

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12 December 2020