Etanercept downregulates the Th17 pathway and decreases the IL-17+/IL-10+ cell ratio in patients with psoriasis vulgaris (Q84380271)

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5 February 2020

title

Etanercept downregulates the Th17 pathway and decreases the IL-17+/IL-10+ cell ratio in patients with psoriasis vulgaris (English)

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1

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Laura Maggi

4

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author name string

Walter Volpi

2

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5 February 2020

Elisa Cardilicchia

3

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Lucia Filì

5

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5 February 2020

Cinzia Manuelli

6

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Paola Parronchi

7

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Paolo Fabbri

8

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Marzia Caproni

9

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publication date

15 June 2012

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Journal of Clinical Immunology

5 February 2020

published in

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volume

32

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issue

6

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page(s)

1221-1232

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A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

5 February 2020

cites work

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12 December 2020

Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation

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12 December 2020

Phenotypic and functional features of human Th17 cells

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Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

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Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling

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Increased Th17 cells are accompanied by FoxP3(+) Treg cell accumulation and correlated with psoriasis disease severity

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Role of CD4CD25FOXP3 Regulatory T Cells in Psoriasis

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T cells involved in psoriasis vulgaris belong to the Th1 subset

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Interplay between TNF and regulatory T cells in a TNF-driven murine model of arthritis.

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Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells

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Immunobiologics in the treatment of psoriasis

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Pathogenesis and therapy of psoriasis

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Interleukin-8-positive neutrophils in psoriasis

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Human slan (6-sulfo LacNAc) dendritic cells are inflammatory dermal dendritic cells in psoriasis and drive strong TH17/TH1 T-cell responses

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12 December 2020

Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

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12 December 2020

Circulating Th17, Th22, and Th1 cells are increased in psoriasis

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Cytokines and anticytokines in psoriasis.

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Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis

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Interleukin (IL)-22, IL-17, IL-23, IL-8, vascular endothelial growth factor and tumour necrosis factor-α levels in patients with psoriasis before, during and after psoralen-ultraviolet A and narrowband ultraviolet B therapy

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The pathogenic role of tissue-resident immune cells in psoriasis.

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Molecular mechanisms of retinoid actions in skin

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The Role of Etanercept on the Expression of Markers of T Helper 17 Cells and Their Precursors in Skin Lesions of Patients with Psoriasis Vulgaris

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Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

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Human Th17 cells in infection and autoimmunity

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The Family of IL-10-secreting CD4+ T cells

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Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

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12 December 2020

Cutting edge: A critical functional role for IL-23 in psoriasis.

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12 December 2020

Circulating CD4+CD25 bright FOXP3+ T cells are up-regulated by biological therapies and correlate with the clinical response in psoriasis patients.

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12 December 2020

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

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12 December 2020

Dynamic frequency of CD4+CD25+Foxp3+ Treg cells in psoriasis vulgaris

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12 December 2020

Serum levels of IL-17 and IL-22 are reduced by etanercept, but not by acitretin, in patients with psoriasis: a randomized-controlled trial

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12 December 2020

Infliximab therapy induces increased polyclonality of CD4+CD25+ regulatory T cells in psoriasis

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12 December 2020

Th1, Th2, Th17 and regulatory T cell pattern in psoriatic patients: modulation of cytokines and gene targets induced by etanercept treatment and correlation with clinical response.

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12 December 2020

Risk of Myocardial Infarction in Patients With Psoriasis

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12 December 2020

IL-17 family cytokines and the expanding diversity of effector T cell lineages

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12 December 2020

Serum IL-22 correlates with psoriatic severity and serum IL-6 correlates with susceptibility to phototherapy

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12 December 2020

Human Th17 cells: are they different from murine Th17 cells?

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12 December 2020

Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes

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12 December 2020

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta

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12 December 2020