Vardenafil, an inhibitor of phosphodiesterase-5, blocks advanced glycation end product (AGE)-induced up-regulation of monocyte chemoattractant protein-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression via elevation of (Q84965630)

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scientific article published on 29 August 2010

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English	Vardenafil, an inhibitor of phosphodiesterase-5, blocks advanced glycation end product (AGE)-induced up-regulation of monocyte chemoattractant protein-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression via elevation of	scientific article published on 29 August 2010

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scholarly article

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Europe PubMed Central

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13 February 2020

Vardenafil, an inhibitor of phosphodiesterase-5, blocks advanced glycation end product (AGE)-induced up-regulation of monocyte chemoattractant protein-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression via elevation of cGMP (English)

1 reference

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13 February 2020

author name string

Yuji Ishibashi

1

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13 February 2020

Takanori Matsui

2

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13 February 2020

Masayoshi Takeuchi

3

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13 February 2020

Sho-ichi Yamagishi

4

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13 February 2020

publication date

29 August 2010

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13 February 2020

Clinical and Experimental Medicine

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13 February 2020

11

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13 February 2020

2

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13 February 2020

131-135

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13 February 2020

https://scigraph.springernature.com/pub.10.1007/s10238-010-0109-2

0 references

Diabetic vascular complications: pathophysiology, biochemical basis and potential therapeutic strategy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20803229

12 December 2020

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The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocin-induced diabetic rats: preventive versus curative treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20803229

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Phosphodiesterase type 5 regulation in the penile corpora cavernosa

1 reference

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12 December 2020

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Kinetics, role and therapeutic implications of endogenous soluble form of receptor for advanced glycation end products (sRAGE) in diabetes

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Novel phosphodiesterase-5 (PDE5) inhibitors in the alleviation of erectile dysfunction due to diabetes and ageing-induced oxidative stress

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RAGE in inflammation: a new therapeutic target?

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Effect of high-fat breakfast and moderate-fat evening meal on the pharmacokinetics of vardenafil, an oral phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction

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Erectile dysfunction as a predictor of cardiovascular events and death in diabetic patients with angiographically proven asymptomatic coronary artery disease: a potential protective role for statins and 5-phosphodiesterase inhibitors

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Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferator-activated receptor-gamma activation

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