The balance between soluble receptors regulating IL-6 trans-signaling is predictive for the RANKL/osteoprotegerin ratio in postmenopausal women with rheumatoid arthritis (Q84990028)

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scientific article published on 07 September 2010

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English	The balance between soluble receptors regulating IL-6 trans-signaling is predictive for the RANKL/osteoprotegerin ratio in postmenopausal women with rheumatoid arthritis	scientific article published on 07 September 2010

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scholarly article

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13 February 2020

The balance between soluble receptors regulating IL-6 trans-signaling is predictive for the RANKL/osteoprotegerin ratio in postmenopausal women with rheumatoid arthritis (English)

1 reference

Europe PubMed Central

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13 February 2020

rheumatoid arthritis

1 reference

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author name string

Peter Oelzner

1

1 reference

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13 February 2020

Sybille Franke

2

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13 February 2020

Gabriele Lehmann

3

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13 February 2020

Thorsten Eidner

4

1 reference

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13 February 2020

Gert Hein

5

1 reference

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13 February 2020

Gunter Wolf

6

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13 February 2020

publication date

7 September 2010

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13 February 2020

Rheumatology International

1 reference

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13 February 2020

32

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13 February 2020

199-206

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13 February 2020

1

1 reference

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13 February 2020

https://scigraph.springernature.com/pub.10.1007/s00296-010-1606-z

0 references

Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum interleukin 6 is a major predictor of bone loss in women specific to the first decade past menopause.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 and its receptor: from bench to bedside

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shedding of the interleukin-6 (IL-6) receptor (gp80) determines the ability of IL-6 to induce gp130 phosphorylation in human osteoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of pyridinium crosslinks of collagen in the synovial fluid of patients with rheumatoid arthritis using high-performance liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic corticosteroid, dexamethasone regulates generation of soluble form of interleukin-6 receptor of human lymphocytes, in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between glucocorticoids and cytokines in the bone microenvironment

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 and osteoprotegerin systems in Paget's disease of bone: relationship to risedronate treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crosstalk between the interleukin-6 (IL-6)-JAK-STAT and the glucocorticoid-nuclear receptor pathway: synergistic activation of IL-6 response element by IL-6 and glucocorticoid

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RANKL is a marker and mediator of local and systemic bone loss in two rat models of inflammatory arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Glucocorticoid induced osteoporosis]

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

gp130-Mediated Signaling Is Necessary for Normal Osteoblastic Functionin Vivoandin Vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circulating levels of C-reactive protein and markers of bone resorption in postmenopausal women

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-talk between the interleukin-6 and prostaglandin E(2) signaling systems results in enhancement of osteoclastogenesis through effects on the osteoprotegerin/receptor activator of nuclear factor-{kappa}B (RANK) ligand/RANK system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum interleukin-6, soluble interleukin-6 receptor and soluble gp130 exhibit different patterns of age- and menopause-related changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

gp130 signaling in bone cell biology: multiple roles revealed by analysis of genetically altered mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of IL-6 and RANK mRNA in human trabecular bone from fragility fracture of the femoral neck.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the interleukin-6/interleukin-6 soluble receptor cytokine system in mediating increased skeletal sensitivity to parathyroid hormone in perimenopausal women

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: influence of osteotropic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of gp130-mediated tyrosine phosphorylation of STAT3 and its DNA-binding activity in dexamethasone-treated AIDS-associated Kaposi's sarcoma cells: selective synergy between dexamethasone and gp130-related growth factors in Kaposi's sarcom

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating levels of inflammatory markers predict change in bone mineral density and resorption in older adults: a longitudinal study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 modulates production of T lymphocyte–derived cytokines in antigen-induced arthritis and drives inflammation-induced osteoclastogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-dose glucocorticoids increase serum levels of soluble IL-6 receptor alpha and its ratio to soluble gp130: an additional mechanism for early increased bone resorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the receptor activator of nuclear factor-kappaB ligand/osteoprotegerin cytokine system in primary hyperparathyroidism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for interleukin-6 in parathyroid hormone-induced bone resorption in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dickkopf-1 is a master regulator of joint remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappa B in mouse calvariae

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between disease activity and serum levels of vitamin D metabolites and PTH in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactive effect of interleukin-6 and prostaglandin E2 on osteoclastogenesis via the OPG/RANKL/RANK system

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of interleukin-6 and prostaglandin E2 in periarticular osteoporosis of postmenopausal women with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6, RANKL, TNF-alpha/IL-1: interrelations in bone resorption pathophysiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/20821212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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