DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials (Q85047234)

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14 February 2020

title

DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials (English)

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main subject

phase I clinical trial

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12

Terrence M Tumpey

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15

Gary J Nabel

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8

Melissa B Pearce

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16

Barney S Graham

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1

Julie E Ledgerwood

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5

Mary E Enama

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14

John R Mascola

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4

Ingelise J Gordon

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13

Richard A Koup

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6

Cynthia S Hendel

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9

Hadi M Yassine

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10

Jeffrey C Boyington

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2

Chih-Jen Wei

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7

Patrick M McTamney

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author name string

Zonghui Hu

series ordinal

3

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Robert Bailer

series ordinal

11

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VRC 306 Study Team

series ordinal

17

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publication date

3 October 2011

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Lancet Infectious Diseases

14 February 2020

published in

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volume

11

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issue

12

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page(s)

916-924

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Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector

14 February 2020

cites work

1 reference

12 December 2020

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

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Antibody recognition of a highly conserved influenza virus epitope

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A West Nile virus DNA vaccine utilizing a modified promoter induces neutralizing antibody in younger and older healthy adults in a phase I clinical trial

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Induction of broadly neutralizing H1N1 influenza antibodies by vaccination

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Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies

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A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains.

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Cross-neutralization of 1918 and 2009 influenza viruses: role of glycans in viral evolution and vaccine design

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The origins of pandemic influenza--lessons from the 1918 virus.

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A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial

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Variation and infectivity neutralization in influenza

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Safety and immunogenicity of influenza A H5 subunit vaccines: effect of vaccine schedule and antigenic variant

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Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

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DNA vaccines: a safe and efficient platform technology for responding to emerging infectious diseases

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Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans

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Wide prevalence of heterosubtypic broadly neutralizing human anti-influenza A antibodies

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A phase 1/2 study of a multiclade HIV-1 DNA plasmid prime and recombinant adenovirus serotype 5 boost vaccine in HIV-Uninfected East Africans (RV 172).

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Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine

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Determinants of immunity to influenza infection in man

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Safety and immunogenicity study of Multiclade HIV-1 adenoviral vector vaccine alone or as boost following a multiclade HIV-1 DNA vaccine in Africa

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Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine

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Enhanced breadth of CD4 T-cell immunity by DNA prime and adenovirus boost immunization to human immunodeficiency virus Env and Gag immunogens

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Human infection with a triple-reassortant swine influenza A(H1N1) virus containing the hemagglutinin and neuraminidase genes of seasonal influenza virus.

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Influenza H5 hemagglutinin DNA primes the antibody response elicited by the live attenuated influenza A/Vietnam/1203/2004 vaccine in ferrets

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Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 DNA candidate vaccine

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Detection of anti-H5 responses in human sera by HI using horse erythrocytes following MF59-adjuvanted influenza A/Duck/Singapore/97 vaccine

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Safety and immunogenicity of a Gag-Pol candidate HIV-1 DNA vaccine administered by a needle-free device in HIV-1-seronegative subjects

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Heterologous HA DNA vaccine prime--inactivated influenza vaccine boost is more effective than using DNA or inactivated vaccine alone in eliciting antibody responses against H1 or H3 serotype influenza viruses.

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A DNA vaccine for Ebola virus is safe and immunogenic in a phase I clinical trial

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Immunization by avian H5 influenza hemagglutinin mutants with altered receptor binding specificity

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Safety and immunogenicity of an inactivated subvirion influenza A (H5N1) vaccine.

1 reference

12 December 2020

A West Nile Virus DNA Vaccine Induces Neutralizing Antibody in Healthy Adults during a Phase 1 Clinical Trial

1 reference

12 December 2020

10.1016/S1473-3099(11)70240-7

Identifiers

DOI

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14 February 2020

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