c-Myc-mediated epigenetic silencing of MicroRNA-101 contributes to dysregulation of multiple pathways in hepatocellular carcinoma (Q85198781)

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15 February 2020

title

c-Myc-mediated epigenetic silencing of MicroRNA-101 contributes to dysregulation of multiple pathways in hepatocellular carcinoma (English)

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15 February 2020

main subject

hepatocellular carcinoma

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Lei Wang

1

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15 February 2020

Xiang Zhang

2

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Lin-Tao Jia

3

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Si-Jun Hu

4

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15 February 2020

Jing Zhao

5

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Jian-Dong Yang

6

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Wei-Hong Wen

7

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Zhe Wang

8

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Tao Wang

9

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Jun Zhao

10

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Rui-An Wang

11

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Yan-Ling Meng

12

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Yong-Zhan Nie

13

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Ke-Feng Dou

14

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Si-Yi Chen

15

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Li-Bo Yao

16

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Dai-Ming Fan

17

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Rui Zhang

18

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An-Gang Yang

19

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publication date

27 March 2014

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15 February 2020

volume

59

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issue

5

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page(s)

1850-1863

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Global cancer statistics, 2002

15 February 2020

cites work

1 reference

7 January 2021

Molecular mechanism of liver cancer

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7 January 2021

MicroRNAs: target recognition and regulatory functions

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7 January 2021

microRNA involvement in hepatocellular carcinoma

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7 January 2021

MicroRNAs in cancer: small molecules with a huge impact

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7 January 2021

MicroRNA signatures in human cancers

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7 January 2021

A microRNA expression signature of human solid tumors defines cancer gene targets

1 reference

7 January 2021

Impaired microRNA processing enhances cellular transformation and tumorigenesis

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7 January 2021

MicroRNA expression profiles classify human cancers

1 reference

7 January 2021

MYC on the path to cancer

1 reference

7 January 2021

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

1 reference

7 January 2021

Etiology-dependent molecular mechanisms in human hepatocarcinogenesis

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7 January 2021

Central role of c-Myc during malignant conversion in human hepatocarcinogenesis

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7 January 2021

Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer

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7 January 2021

Widespread microRNA repression by Myc contributes to tumorigenesis

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7 January 2021

The Polycomb complex PRC2 and its mark in life

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7 January 2021

EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies

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7 January 2021

Aberrations of EZH2 in cancer

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7 January 2021

Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin.

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7 January 2021

The role of EZH2 in tumour progression

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7 January 2021

Identification of a two-layer regulatory network of proliferation-related microRNAs in hepatoma cells

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7 January 2021

MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma

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7 January 2021

MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity

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7 January 2021

Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma

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7 January 2021

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

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7 January 2021

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

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7 January 2021

Involvement of OP18 in cell proliferation

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7 January 2021

CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration.

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7 January 2021

Critical role for NF-kappaB-induced JunB in VEGF regulation and tumor angiogenesis

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7 January 2021

Myc-mediated transcriptional repression by recruitment of histone deacetylase.

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7 January 2021

Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression

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7 January 2021

Context-specific regulation of NF-κB target gene expression by EZH2 in breast cancers.

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7 January 2021

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2

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7 January 2021

Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor.

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7 January 2021

Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis.

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7 January 2021

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

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7 January 2021

The Polycomb group protein EZH2 directly controls DNA methylation

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7 January 2021

Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas

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7 January 2021

Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway

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7 January 2021

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

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7 January 2021

Embryonic ectoderm development protein is regulated by microRNAs in human neural tube defects.

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7 January 2021

MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

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7 January 2021

The global health burden of infection-associated cancers in the year 2002

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7 January 2021

Identifiers

DOI

10.1002/HEP.26720

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15 February 2020

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