Bicoid Dmel_CG1034 (Q856848)

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Protein found in Drosophila melanogaster

CG1034-PF
PRD gene 4
bcd-PE
bcd
CG1034-PE
multimorph
bcd-PF
CG1034 gene product from transcript CG1034-RA
CG1034-PA
CG1034-PD
bcd-PG
CG1034-PG
bcd-PD
bicoid
bcd-PA

Language	Label	Description	Also known as
English	Bicoid Dmel_CG1034	Protein found in Drosophila melanogaster	CG1034-PF PRD gene 4 bcd-PE bcd CG1034-PE multimorph bcd-PF CG1034 gene product from transcript CG1034-RA CG1034-PA CG1034-PD bcd-PG CG1034-PG bcd-PD bicoid bcd-PA

Statements

1 reference

25 May 2022

UniProt protein ID

0 references

Homeobox-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09081

Homeobox domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Homeobox, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

2 references

DNA-binding transcription factor activity

determination method

1 reference

16 July 2018

Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

determination method

1 reference

10 September 2018

Enhancer sequences influence the role of the amino-terminal domain of bicoid in transcription

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

mRNA 3'-UTR binding

determination method

1 reference

8 April 2019

A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

protein binding

determination method

8 references

8 April 2019

Identification of drosophila bicoid-interacting proteins using a custom two-hybrid selection.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

8 April 2019

Drosophila SAP18, a member of the Sin3/Rpd3 histone deacetylase complex, interacts with Bicoid and inhibits its activity.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

8 April 2019

Drosophila Bicoid is a substrate of sumoylation and its activator function is subject to inhibition by this post-translational modification

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

8 April 2019

Identification of drosophila bicoid-interacting proteins using a custom two-hybrid selection.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

8 April 2019

Drosophila SAP18, a member of the Sin3/Rpd3 histone deacetylase complex, interacts with Bicoid and inhibits its activity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

8 April 2019

Fates-shifted is an F-box protein that targets Bicoid for degradation and regulates developmental fate determination in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

8 April 2019

A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

8 April 2019

Identification of drosophila bicoid-interacting proteins using a custom two-hybrid selection.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

morphogen activity

determination method

1 reference

24 April 2018

Precision patterning.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

translation repressor activity

determination method

1 reference

8 April 2019

A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

sequence-specific DNA binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

translation regulator activity

determination method

1 reference

8 April 2019

Translational repressors in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

1 reference

8 April 2019

Enhancer sequences influence the role of the amino-terminal domain of bicoid in transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

8 April 2019

Enhancer sequences influence the role of the amino-terminal domain of bicoid in transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

biological process

transcription, DNA-templated

determination method

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

regulation of transcription, DNA-templated

determination method

4 references

24 April 2018

Conservation and divergence in molecular mechanisms of axis formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

24 April 2018

Antagonistic action of Bicoid and the repressor Capicua determines the spatial limits of Drosophila head gene expression domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

regulation of transcription by RNA polymerase II

determination method

1 reference

24 April 2018

Precision patterning.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

regulation of translation

determination method

1 reference

24 April 2018

Translational repressors in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

multicellular organism development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

anterior region determination

determination method

1 reference

8 April 2019

Sap18 is required for the maternal gene bicoid to direct anterior patterning in Drosophila melanogaster.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

segment polarity determination

determination method

1 reference

8 April 2019

Mis-specified cells die by an active gene-directed process, and inhibition of this death results in cell fate transformation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

maternal determination of anterior/posterior axis, embryo

determination method

3 references

24 April 2018

Runt and Lozenge function in Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

24 April 2018

Sharp borders from fuzzy gradients.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

24 April 2018

Transcriptional repression: the long and the short of it.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

anterior/posterior axis specification, embryo

determination method

4 references

24 April 2018

Signal transduction pathway for anterior-posterior development in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

24 April 2018

The polarisation of the anteroposterior axis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

24 April 2018

Precision patterning.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

24 April 2018

Conservation and divergence in molecular mechanisms of axis formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

anterior/posterior axis specification

determination method

1 reference

8 April 2019

Evolution of development: beyond bicoid

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

regulation of signaling receptor activity

determination method

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

negative regulation of translation

determination method

4 references

24 April 2018

Conservation and divergence in molecular mechanisms of axis formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

24 April 2018

Evolution of development: beyond bicoid

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

24 April 2018

MicroRNAs act as cofactors in bicoid-mediated translational repression.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

24 April 2018

A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09081&geneProductId=UniProtKB:P09081

determination method

determination method

1 reference

8 April 2019

Sap18 is required for the maternal gene bicoid to direct anterior patterning in Drosophila melanogaster.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

anterior/posterior axis specification, embryo

determination method

1 reference

8 April 2019

Signal transduction pathway for anterior-posterior development in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

positive regulation of transcription by RNA polymerase II

determination method

3 references

8 April 2019

Enhancer sequences influence the role of the amino-terminal domain of bicoid in transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

8 April 2019

Drosophila Goosecoid requires a conserved heptapeptide for repression of paired-class homeoprotein activators.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09081

determination method

Homeobox, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09081

Homeobox domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09081

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Google Knowledge Graph ID

0 references

Sitelinks

Wikipedia(1 entry)

dewiki Bicoid

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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