Aggrecanases in the human synovial fluid at different stages of osteoarthritis (Q86032618)

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23 February 2020

title

Aggrecanases in the human synovial fluid at different stages of osteoarthritis (English)

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23 February 2020

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Enshui Zhang

1

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23 February 2020

Xinfeng Yan

2

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23 February 2020

Ming Zhang

3

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23 February 2020

Xiaotian Chang

4

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23 February 2020

Zhengwu Bai

5

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23 February 2020

Yeteng He

6

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23 February 2020

Zhen Yuan

7

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23 February 2020

publication date

31 January 2013

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23 February 2020

published in

Clinical Rheumatology

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23 February 2020

volume

32

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23 February 2020

issue

6

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23 February 2020

page(s)

797-803

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Aggrecanolysis in human osteoarthritis: confocal localization and biochemical characterization of ADAMTS5–hyaluronan complexes in articular cartilages

23 February 2020

cites work

1 reference

12 December 2020

Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration

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12 December 2020

Abnormalities of articular cartilage in the knee: analysis of available MR techniques

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12 December 2020

Cartilage in normal and osteoarthritis conditions

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12 December 2020

Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing i

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12 December 2020

Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments

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12 December 2020

Expression profiling of metalloproteinases and their inhibitors in cartilage

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12 December 2020

MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein

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12 December 2020

FURTHER STUDIES ON THE ETIOLOGY OF CHONDROMALACIA PATELLAE

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12 December 2020

The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation

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12 December 2020

Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro

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12 December 2020

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

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12 December 2020

Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips

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12 December 2020

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association

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12 December 2020

Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity

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12 December 2020

The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis

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12 December 2020

Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5.

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12 December 2020

Distribution of aggrecanase (ADAMts 4/5) cleavage products in normal and osteoarthritic human articular cartilage: the influence of age, topography and zone of tissue

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12 December 2020

Cytokine and catabolic enzyme expression in synovium, synovial fluid and articular cartilage of naturally osteoarthritic equine carpi

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12 December 2020

Quantitative MRI of cartilage and bone: degenerative changes in osteoarthritis

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12 December 2020

The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage

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12 December 2020

Accuracy and precision of quantitative assessment of cartilage morphology by magnetic resonance imaging at 3.0T

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12 December 2020

Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation

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12 December 2020

Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan. Evidence for proteolysis at this site in vivo in human articular cartilage

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12 December 2020

Low molecular weight isoforms of the aggrecanases are responsible for the cytokine-induced proteolysis of aggrecan in a porcine chondrocyte culture system

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12 December 2020

Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4.

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12 December 2020

Evidence of a novel aggrecan-degrading activity in cartilage: Studies of mice deficient in both ADAMTS-4 and ADAMTS-5.

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12 December 2020

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

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12 December 2020

Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro.

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12 December 2020

The regulation of the ADAMTS4 and ADAMTS5 aggrecanases in osteoarthritis: a review

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12 December 2020

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

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12 December 2020

Products resulting from cleavage of the interglobular domain of aggrecan in samples of synovial fluid collected from dogs with early- and late-stage osteoarthritis

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12 December 2020

Matrix turnover in human cartilage repair tissue in autologous chondrocyte implantation.

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12 December 2020

10.1007/S10067-013-2171-0

Identifiers

DOI

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23 February 2020

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