Common quantitative trait locus downstream of RETN gene identified by genome-wide association study is associated with risk of type 2 diabetes mellitus in Han Chinese: a Mendelian randomization effect (Q86524508)

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scientific article published on 01 March 2014

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English	Common quantitative trait locus downstream of RETN gene identified by genome-wide association study is associated with risk of type 2 diabetes mellitus in Han Chinese: a Mendelian randomization effect	scientific article published on 01 March 2014

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scholarly article

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27 February 2020

Common quantitative trait locus downstream of RETN gene identified by genome-wide association study is associated with risk of type 2 diabetes mellitus in Han Chinese: a Mendelian randomization effect (English)

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type 2 diabetes

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genome-wide association study

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quantitative trait locus

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metabolic trait

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author name string

Chia-Min Chung

1

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Tsung-Hsien Lin

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Jaw-Wen Chen

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Hsin-Bang Leu

4

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Wei-Hsian Yin

5

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Hung-Yun Ho

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Sheng-Hsiung Sheu

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Wei-Chuan Tsai

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Jyh-Hong Chen

9

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Shing-Jong Lin

10

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Wen-Harn Pan

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publication date

1 March 2014

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Diabetes - Metabolism: Research and Reviews

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232-240

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3

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describes a project that uses

genome-wide association study

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The hormone resistin links obesity to diabetes

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A promoter genotype and oxidative stress potentially link resistin to human insulin resistance

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Resistin polymorphisms are associated with cerebrovascular disease in Finnish Type 2 diabetic patients

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Systematic search for single nucleotide polymorphisms in the resistin gene: the absence of evidence for the association of three identified single nucleotide polymorphisms with Japanese type 2 diabetes

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Human resistin gene, obesity, and type 2 diabetes: mutation analysis and population study

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FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family

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Resistin decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells

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Tissue factor is induced by resistin in human coronary artery endothelial cells by the NF-ĸB-dependent pathway

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Adipokine resistin promotes in vitro angiogenesis of human endothelial cells

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Resistin promotes smooth muscle cell proliferation through activation of extracellular signal-regulated kinase 1/2 and phosphatidylinositol 3-kinase pathways.

1 reference

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Plasma resistin levels and risk of myocardial infarction and ischemic stroke

1 reference

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Circulating levels of resistin and risk of type 2 diabetes in men and women: results from two prospective cohorts

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

7 January 2021

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Resistin and cardiovascular disease

1 reference

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What can mendelian randomisation tell us about modifiable behavioural and environmental exposures?

1 reference

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7 January 2021

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Effect of the -420C/G variant of the resistin gene promoter on metabolic syndrome, obesity, myocardial infarction and kidney dysfunction.

1 reference

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Heritability of genetic variants of resistin gene in patients with coronary artery disease: a family-based study

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

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based on heuristic

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Heritability of serum resistin and its genetic correlation with insulin resistance-related features in nondiabetic Caucasians.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

7 January 2021

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The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3

1 reference

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Plasma resistin concentration determined by common variants in the resistin gene and associated with metabolic traits in an aged Japanese population.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

7 January 2021

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Association of variants in RETN with plasma resistin levels and diabetes-related traits in the Framingham Offspring Study

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

7 January 2021

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https://api.crossref.org/works/10.1002%2FDMRR.2481

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A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

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PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

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based on heuristic

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Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

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based on heuristic

inferred from DOI database lookup

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

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based on heuristic

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Resistin release by human adipose tissue explants in primary culture

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Resistin messenger-RNA expression is increased by proinflammatory cytokines in vitro.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistin is expressed in human macrophages and directly regulated by PPAR gamma activators

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

7 January 2021

based on heuristic

inferred from DOI database lookup

An inflammatory cascade leading to hyperresistinemia in humans

1 reference

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7 January 2021

based on heuristic

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Resistin is an inflammatory marker of atherosclerosis in humans.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine-endothelial cell interactions

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

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based on heuristic

inferred from DOI database lookup

Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

7 January 2021

based on heuristic

inferred from DOI database lookup

Plasma resistin levels correlate with determinants of the metabolic syndrome.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.2481

7 January 2021

based on heuristic

inferred from DOI database lookup

Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL cholesterol, and high-sensitivity C-reactive protein in the Japanese general population.

1 reference

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based on heuristic

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1 reference

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based on heuristic

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A at single nucleotide polymorphism-358 is required for G at -420 to confer the highest plasma resistin in the general Japanese population

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Identifiers

10.1002/DMRR.2481

1 reference

Europe PubMed Central

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27 February 2020

1 reference

Europe PubMed Central

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