Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology (Q87041979)

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4 March 2020

review article

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title

Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25835361%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

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Salvia miltiorrhiza

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Chun-Yan Su

1

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4 March 2020

Qian-Liang Ming

2

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4 March 2020

Khalid Rahman

3

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4 March 2020

Ting Han

4

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4 March 2020

Lu-Ping Qin

5

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4 March 2020

publication date

1 March 2015

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4 March 2020

volume

13

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4 March 2020

issue

3

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4 March 2020

page(s)

163-182

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Pharmacological evidence for calcium channel inhibition by danshen (Salvia miltiorrhiza) on rat isolated femoral artery

4 March 2020

cites work

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7 January 2021

In Salvia miltiorrhiza, phenolic acids possess protective properties against amyloid β-induced cytotoxicity, and tanshinones act as acetylcholinesterase inhibitors

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7 January 2021

Cryptotanshinone, an acetylcholinesterase inhibitor from Salvia miltiorrhiza, ameliorates scopolamine-induced amnesia in Morris water maze task.

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7 January 2021

Protocatechuic acid inhibits neurotoxicity induced by MPTP in vivo

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7 January 2021

Lithospermic acid B isolated from Salvia miltiorrhiza ameliorates ischemia/reperfusion-induced renal injury in rats

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7 January 2021

In vitro protective effects of salvianolic acid B on primary hepatocytes and hepatic stellate cells

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7 January 2021

Effects of salvianolic acid a on oxidative stress and liver injury induced by carbon tetrachloride in rats

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7 January 2021

Salvianolic acid B from Salvia miltiorrhiza inhibits tumor necrosis factor-alpha (TNF-alpha)-induced MMP-2 upregulation in human aortic smooth muscle cells via suppression of NAD(P)H oxidase-derived reactive oxygen species

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7 January 2021

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7 January 2021

Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use

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7 January 2021

Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function

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7 January 2021

Cardiovascular actions and therapeutic potential of tanshinone IIA.

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7 January 2021

In vitro cytotoxicity of tanshinones from Salvia miltiorrhiza

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7 January 2021

Two novel abietane diterpenes from Salvia miltiorrhiza

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7 January 2021

Structure elucidation and total synthesis of new tanshinones isolated from Salvia miltiorrhiza Bunge (Danshen)

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7 January 2021

New developments in the chemistry and biology of the bioactive constituents of Tanshen

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7 January 2021

Pigments from Salvia miltiorrhiza

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7 January 2021

Characterization of tanshinones in the roots of Salvia miltiorrhiza (Dan-shen) by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry

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7 January 2021

Extraction and preparative purification of tanshinones from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography.

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7 January 2021

Diterpenoids from Salvia miltiorrhiza

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7 January 2021

Multi-component HPLC fingerprinting of Radix Salviae Miltiorrhizae and its LC-MS-MS identification

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7 January 2021

Antioxidative components of tanshen (Salvia miltiorhiza Bung)

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7 January 2021

Characterization of tanshinones with quinone reductase induction activity from Radix Salvia miltiorrhiza by liquid chromatography/tandem mass spectrometry

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7 January 2021

Diterpenoids from Salvia glutinosa, S. austriaca, S. tomentosa and S. verticillata roots

1 reference

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7 January 2021

Effects of purified herbal extract of Salvia miltiorrhiza on ischemic rat myocardium after acute myocardial infarction.

1 reference

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7 January 2021

Advancement in analysis of Salviae miltiorrhizae Radix et Rhizoma (Danshen).

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7 January 2021

Isolation and bioactivity of new tanshinones

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7 January 2021

PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza.

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7 January 2021

18-Oxoferruginol from the leaf of Torreya nucifera

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7 January 2021

Cytotoxic abietane diterpenoids from Caryopteris incana

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7 January 2021

Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1.

1 reference

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7 January 2021

Trijuganone A and B: Two New Phenanthrenequinones from Roots of Salvia trijuga

1 reference

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7 January 2021

Chemistry and biological activities of caffeic acid derivatives from Salvia miltiorrhiza

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7 January 2021

Salvianolic Acids D and E: Two New Depsides from Salvia miltiorrhiza

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7 January 2021

Salvianolic Acid A, a New Depside from Roots of Salvia miltiorrhiza

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7 January 2021

Antioxidant effect ofSalvia miltiorrhiza

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7 January 2021

Isolation of inhibitors of adenylate cyclase from dan-shen, the root of Salvia miltiorrhiza

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7 January 2021

Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells

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7 January 2021

Further isolation of antioxidative (+)-1-hydroxypinoresinol-1-O-beta-D-glucoside from the rhizome of Salvia miltiorrhiza that acts on peroxynitrite, total ROS and 1,1-diphenyl-2-picrylhydrazyl radical

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7 January 2021

Stereostructure of Salvianolic Acid B and Isolation of Salvianolic Acid C from Salvia miltiorrhiza

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7 January 2021

Rapid separation and identification of phenolic and diterpenoid constituents from Radix Salvia miltiorrhizae by high-performance liquid chromatography diode-array detection, electrospray ionization time-of-flight mass spectrometry and electrospray i

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7 January 2021

Salvianolic Acid I: A New Depside from Salvia cavaleriei

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7 January 2021

Salvianolic acid J, a depside from Salvia flava

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7 January 2021

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7 January 2021

Cytotoxic and aromatic constituents from Salvia miltiorrhiza

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7 January 2021

Antitumor Agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza

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7 January 2021

Protective effects of Danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen) against homocysteine-induced endothelial dysfunction

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7 January 2021

Heme oxygenase-1: the "emerging molecule" has arrived

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7 January 2021

Extract of Salvia miltiorrhiza (Danshen) induces Nrf2-mediated heme oxygenase-1 expression as a cytoprotective action in RAW 264.7 macrophages.

1 reference

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7 January 2021

Proteomic screening of antioxidant effects exhibited by radix Salvia miltiorrhiza aqueous extract in cultured rat aortic smooth muscle cells under homocysteine treatment

1 reference

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7 January 2021

Dual effects of lipophilic extract of Salvia miltiorrhiza (Danshen) on catecholamine secretion in cultured bovine adrenal medullary cells

1 reference

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7 January 2021

Salvia miltiorrhiza (Danshen) injection ameliorates iron overload-induced cardiac damage in mice

1 reference

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7 January 2021

Protocatechuic aldehyde inhibits lipopolysaccharide-induced human umbilical vein endothelial cell apoptosis via regulation of caspase-3.

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Inhibitory effect of Salvia miltiorrhia BGE on matrix metalloproteinase-9 activity and migration of TNF-alpha-induced human aortic smooth muscle cells.

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7 January 2021

The pathogenesis of atherosclerosis: a perspective for the 1990s

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7 January 2021

Inhibitory effects of lithospermic acid on proliferation and migration of rat vascular smooth muscle cells

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7 January 2021

Tanshinone IIA inhibits smooth muscle proliferation and intimal hyperplasia in the rat carotid balloon-injured model through inhibition of MAPK signaling pathway

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7 January 2021

The anti-atherosclerotic effect of tanshinone IIA is associated with the inhibition of TNF-α-induced VCAM-1, ICAM-1 and CX3CL1 expression.

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7 January 2021

Functional proteomics reveal the effect of Salvia miltiorrhiza aqueous extract against vascular atherosclerotic lesions

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7 January 2021

Tanshinone IIA inhibits atherosclerotic plaque formation by down-regulating MMP-2 and MMP-9 expression in rabbits fed a high-fat diet

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7 January 2021

Biphasic effects of sodium danshensu on vessel function in isolated rat aorta

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7 January 2021

Activation of high conductance Ca(2+)-activated K(+) channels by sodium tanshinoneII-A sulfonate (DS-201) in porcine coronary artery smooth muscle cells

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7 January 2021

Effects of sodium tanshinone II A sulphonate on hypoxic pulmonary hypertension in rats in vivo and on Kv2.1 expression in pulmonary artery smooth muscle cells in vitro.

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7 January 2021

Hypolipidemic activity and mechanism of purified herbal extract of Salvia miltiorrhiza in hyperlipidemic rats

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7 January 2021

Aqueous extract of danshen (Salvia miltiorrhiza Bunge) protects ovariectomized rats fed with high-fat diet from endothelial dysfunction.

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7 January 2021

Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis.

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7 January 2021

Tanshinone IIA increases recruitment of bone marrow mesenchymal stem cells to infarct region via up-regulating stromal cell-derived factor-1/CXC chemokine receptor 4 axis in a myocardial ischemia model

1 reference

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7 January 2021

Pro-angiogenic actions of Salvianolic acids on in vitro cultured endothelial progenitor cells and chick embryo chorioallantoic membrane model

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7 January 2021

Salvianolic acid A promotes the acceleration of neovascularization in the ischemic rat myocardium and the functions of endothelial progenitor cells

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7 January 2021

Cryptotanshinone, a lipophilic compound of Salvia miltiorrriza root, inhibits TNF-alpha-induced expression of adhesion molecules in HUVEC and attenuates rat myocardial ischemia/reperfusion injury in vivo

1 reference

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7 January 2021

Effect of Danshen aqueous extract on serum hs-CRP, IL-8, IL-10, TNF-α levels, and IL-10 mRNA, TNF-α mRNA expression levels, cerebral TGF-β1 positive expression level and its neuroprotective mechanisms in CIR rats

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7 January 2021

Inflammatory mediators and modulation of blood-brain barrier permeability

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7 January 2021

The blood-brain barrier: an overview: structure, regulation, and clinical implications

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7 January 2021

The effects of Tanshinone IIA on blood-brain barrier and brain edema after transient middle cerebral artery occlusion in rats

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7 January 2021

CREB and cAMP response element-mediated gene expression in the ischemic brain

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7 January 2021

TORCs: transducers of regulated CREB activity

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7 January 2021

Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins

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7 January 2021

The neuroprotective effects of Tanshinone IIA are associated with induced nuclear translocation of TORC1 and upregulated expression of TORC1, pCREB and BDNF in the acute stage of ischemic stroke

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7 January 2021

Cerebral protection of salvianolic acid A by the inhibition of granulocyte adherence

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7 January 2021

Neuroprotective effects of tanshinone I from Danshen extract in a mouse model of hypoxia-ischemia

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7 January 2021

Salvianolic acid B modulates hemostasis properties of human umbilical vein endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Salvianolic acid A inhibits platelet activation and arterial thrombosis via inhibition of phosphoinositide 3-kinase

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7 January 2021

Antiplatelet and antithrombotic activities of salvianolic acid A.

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7 January 2021

Effects of tanshinone IIA, a major component of Salvia miltiorrhiza, on platelet aggregation in healthy newborn piglets

1 reference

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7 January 2021

Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42.

1 reference

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7 January 2021

Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Cryptotanshinione inhibits β-amyloid aggregation and protects damage from β-amyloid in SH-SY5Y cells

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7 January 2021

Salvianolic acid A, a polyphenolic derivative from Salvia miltiorrhiza bunge, as a multifunctional agent for the treatment of Alzheimer's disease

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7 January 2021

Salvianolic acid B, an antioxidant from Salvia miltiorrhiza, prevents 6-hydroxydopamine induced apoptosis in SH-SY5Y cells

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7 January 2021

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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7 January 2021

Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action.

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7 January 2021

Salvianolic acid B and its liposomal formulations: Anti-hyperalgesic activity in the treatment of neuropathic pain

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7 January 2021

The oxidative response in the chronic constriction injury model of neuropathic pain

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7 January 2021

Cryptotanshinone from Salviae miltiorrhizae radix inhibits sodium-nitroprusside-induced apoptosis in neuro-2a cells

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7 January 2021

Insulin-sensitizing activities of tanshinones, diterpene compounds of the root of Salvia miltiorrhiza Bunge

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7 January 2021

Type 2 diabetes severely impairs structural and functional adaptation of rat resistance arteries to chronic changes in blood flow

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7 January 2021

Inhibition of glucose-induced vascular endothelial growth factor expression by Salvia miltiorrhiza hydrophilic extract in human microvascular endothelial cells: evidence for mitochondrial oxidative stress

1 reference

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7 January 2021

Salvianolic acid A protects against vascular endothelial dysfunction in high-fat diet fed and streptozotocin-induced diabetic rats

1 reference

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7 January 2021

Ailanthoidol suppresses lipopolysaccharide-stimulated inflammatory reactions in RAW264.7 cells and endotoxin shock in mice

1 reference

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7 January 2021

Cryptotanshinone suppressed inflammatory cytokines secretion in RAW264.7 macrophages through inhibition of the NF-κB and MAPK signaling pathways

1 reference

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7 January 2021

Role of Salvia miltiorrhiza for Modulation of Th2-derived Cytokines in the Resolution of Inflammation

1 reference

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7 January 2021

Effects of dexamethasone and Salvia miltiorrhizae on the small intestine and immune organs of rats with severe acute pancreatitis

1 reference

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7 January 2021

Salvianolic acid A protects RPE cells against oxidative stress through activation of Nrf2/HO-1 signaling

1 reference

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7 January 2021

Peroxyl radical scavenging capacity of extracts and isolated components from selected medicinal plants

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7 January 2021

Antioxidant activities of leaf extract of Salvia miltiorrhiza Bunge and related phenolic constituents

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https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Antioxidant activity of extracts from leaves and roots of Salvia miltiorrhiza Bunge, S. przewalskii Maxim., and S. verticillata L

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Active Component of Danshen (Salvia miltiorrhiza Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Cryptotanshinone enhances TNF-α-induced apoptosis in chronic myeloid leukemia KBM-5 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Tanshinone IIA activates calcium-dependent apoptosis signaling pathway in human hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Inhibitory effects of tanshinone II-A on invasion and metastasis of human colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Modulation of growth and angiogenic potential of oral squamous carcinoma cells in vitro using salvianolic acid B.

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Tanshinones from Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Apoptosis in liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

PF2401-SF, standardized fraction of Salvia miltiorrhiza and its constituents, tanshinone I, tanshinone IIA, and cryptotanshinone, protect primary cultured rat hepatocytes from bile acid-induced apoptosis by inhibiting JNK phosphorylation.

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Preventive effects of a purified extract isolated from Salvia miltiorrhiza enriched with tanshinone I, tanshinone IIA and cryptotanshinone on hepatocyte injury in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Proteomic analysis of protective effects of polysaccharides from Salvia miltiorrhiza against immunological liver injury in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Hepatoprotective effect of cryptotanshinone from Salvia miltiorrhiza in D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure.

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Salvianolic acid A preconditioning confers protection against concanavalin A-induced liver injury through SIRT1-mediated repression of p66shc in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Epidemiology of acute lung injury and acute respiratory distress syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

The lung in sepsis: guilty or innocent?

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Expression and localization of epithelial aquaporins in the adult human lung

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Membrane trafficking of AQP5 and cAMP dependent phosphorylation in bronchial epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Tanshinone IIA ameliorates seawater exposure-induced lung injury by inhibiting aquaporins (AQP) 1 and AQP5 expression in lung.

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Danshen (Salvia miltiorrhiza) injection suppresses kidney injury induced by iron overload in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Renoprotection of Danshen Injection on streptozotocin-induced diabetic rats, associated with tubular function and structure

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Renoprotective effect of Tanshinone IIA, an active component of Salvia miltiorrhiza, on rats with chronic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

In vitro anti-fibrotic activities of herbal compounds and herbs.

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Antifibrotic effects of magnesium lithospermate B on hepatic stellate cells and thioacetamide-induced cirrhotic rats

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

PF2401-SF, standardized fraction of Salvia miltiorrhiza, induces apoptosis of activated hepatic stellate cells in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Potential use of medicinal plants in the treatment of alcoholism

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Anti-relapse properties of IDN 5082, a standardized extract of Salvia miltiorrhiza, in alcohol-preferring rats

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Identification of miltirone as active ingredient of Salvia miltiorrhiza responsible for the reducing effect of root extracts on alcohol intake in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Angiogenesis of the Frozen‐Thawed Human Fetal Ovarian Tissue at the Early Stage after Xenotransplantation and the Positive Effect of Salviae miltiorrhizae

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Tanshinone II A inhibits tat-induced HIV-1 transactivation through redox-regulated AMPK/Nampt pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

The Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UV

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Cardiovascular effects of Danshen

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Chinese herbs and warfarin potentiation by 'Danshen'

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Interaction between warfarin and danshen (Salvia miltiorrhiza)

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Inhibition of warfarin hydroxylation by major tanshinones of Danshen (Salvia miltiorrhiza) in the rat in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

The effects of Danshen (Salvia miltiorrhiza) on warfarin pharmacodynamics and pharmacokinetics of warfarin enantiomers in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Effect of Chinese medicines Chan Su and Danshen on EMIT 2000 and Randox digoxin immunoassays: wide variation in digoxin-like immunoreactivity and magnitude of interference in digoxin measurement by different brands of the same product

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

Positive and negative in vitro interference of Chinese medicine dan shen in serum digoxin measurement. Elimination of interference by monitoring free digoxin concentration

1 reference

https://api.crossref.org/works/10.1016%2FS1875-5364%2815%2930002-9

7 January 2021

10.1016/S1875-5364(15)30002-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25835361%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference