A PGC-1α- and muscle fibre type-related decrease in markers of mitochondrial oxidative metabolism in skeletal muscle of humans with inherited insulin resistance (Q87258633)

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scientific article published on 09 February 2014

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English	A PGC-1α- and muscle fibre type-related decrease in markers of mitochondrial oxidative metabolism in skeletal muscle of humans with inherited insulin resistance	scientific article published on 09 February 2014

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scholarly article

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7 March 2020

A PGC-1α- and muscle fibre type-related decrease in markers of mitochondrial oxidative metabolism in skeletal muscle of humans with inherited insulin resistance (English)

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7 March 2020

insulin resistance

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Jonas Møller Kristensen

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7 March 2020

Niels Ørtenblad

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7 March 2020

Jørgen Wojtaszewski

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7 March 2020

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Vibe Skov

2

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7 March 2020

Stine J Petersson

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7 March 2020

Henning Beck-Nielsen

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7 March 2020

Kurt Højlund

7

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7 March 2020

publication date

9 February 2014

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7 March 2020

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7 March 2020

57

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7 March 2020

5

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7 March 2020

1006-1015

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7 March 2020

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pioglitazone enhances mitochondrial biogenesis and ribosomal protein biosynthesis in skeletal muscle in polycystic ovary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PGC-1alpha regulation by exercise training and its influences on muscle function and insulin sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic Syndromes of Severe Insulin Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of adiponectin multimers and the IGF axis in humans with a heterozygote mutation in the tyrosine kinase domain of the insulin receptor gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin signaling meets mitochondria in metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced Expression of Nuclear-Encoded Genes Involved in Mitochondrial Oxidative Metabolism in Skeletal Muscle of Insulin-Resistant Women With Polycystic Ovary Syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of glycogen synthase COOH- and NH2-terminal phosphorylation by insulin in obesity and type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPK activity and isoform protein expression are similar in muscle of obese subjects with and without type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle mitochondrial ATP synthesis and glucose transport/phosphorylation in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide content is increased in skeletal muscle from obese insulin-resistant humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of AMPKalpha2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial Respiration Is Decreased in Skeletal Muscle of Patients With Type 2 Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proteomic signature of insulin-resistant human skeletal muscle reveals increased glycolytic and decreased mitochondrial enzymes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of strength training on muscle fiber types and size; consequences for athletes training for high-intensity sport

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete failure of insulin-transmitted signaling, but not obesity-induced insulin resistance, impairs respiratory chain function in muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated plasma adiponectin in humans with genetically defective insulin receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of glycogen availability in sarcoplasmic reticulum Ca2+ kinetics in human skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partial rescue of in vivo insulin signalling in skeletal muscle by impaired insulin clearance in heterozygous carriers of a mutation in the insulin receptor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of mitochondria in insulin resistance and type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional control of mitochondrial biogenesis and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variance stabilization applied to microarray data calibration and to the quantification of differential expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor coactivator-1 mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lower intrinsic ADP-stimulated mitochondrial respiration underlies in vivo mitochondrial dysfunction in muscle of male type 2 diabetic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

International physical activity questionnaire: 12-country reliability and validity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction in patients with primary congenital insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24510228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-014-3187-Y

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24510228%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24510228%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

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