Double incretin receptor knock-out (DIRKO) mice present with alterations of trabecular and cortical micromorphology and bone strength (Q87587380)

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12 March 2020

title

Double incretin receptor knock-out (DIRKO) mice present with alterations of trabecular and cortical micromorphology and bone strength (English)

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4

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Nigel Irwin

6

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Guillaume Mabilleau

8

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author name string

A Mieczkowska

1

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S Mansur

2

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B Bouvard

3

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B Thorens

5

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D Chappard

7

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publication date

16 August 2014

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Osteoporosis International

12 March 2020

published in

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volume

26

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issue

1

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page(s)

209-218

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Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene.

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Ultrastructural properties in cortical bone vary greatly in two inbred strains of mice as assessed by synchrotron light based micro- and nano-CT.

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Strength of cancellous bone trabecular tissue from normal, ovariectomized and drug-treated rats over the course of ageing.

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Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1

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Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis.

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Glucose-dependent insulinotropic peptide-overexpressing transgenic mice have increased bone mass

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Presence of a functional receptor for GLP-1 in osteoblastic cells, independent of the cAMP-linked GLP-1 receptor

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Optimal bone mechanical and material properties require a functional glucagon-like peptide-1 receptor

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Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice.

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Gipr is essential for adrenocortical steroidogenesis; however, corticosterone deficiency does not mediate the favorable metabolic phenotype of Gipr(-/-) mice

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Basic biomechanical measurements of bone: a tutorial

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Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation.

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Receptors and effects of gut hormones in three osteoblastic cell lines

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Spectroscopic characterization of collagen cross-links in bone

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Cortical bone in the human femoral neck: three-dimensional appearance and porosity using synchrotron radiation.

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Glucose-dependent insulinotropic polypeptide receptor deficiency leads to modifications of trabecular bone volume and quality in mice

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Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor

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Validation of quantitative backscattered electron imaging for the measurement of mineral density distribution in human bone biopsies

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Biology of incretins: GLP-1 and GIP

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Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain

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Measurement of the toughness of bone: a tutorial with special reference to small animal studies

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The murine glucagon-like peptide-1 receptor is essential for control of bone resorption.

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Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion

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Genetically based influences on the site-specific regulation of trabecular and cortical bone morphology.

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12 December 2020

The ratio 1660/1690 cm(-1) measured by infrared microspectroscopy is not specific of enzymatic collagen cross-links in bone tissue

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12 December 2020

Standardized nomenclature, symbols, and units for bone histomorphometry: a 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

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12 December 2020

Identification of determinants of glucose-dependent insulinotropic polypeptide receptor that interact with N-terminal biologically active region of the natural ligand.

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12 December 2020

Glucose-dependent insulinotropic polypeptide (GIP) receptor deletion leads to reduced bone strength and quality.

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12 December 2020

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

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12 December 2020

Gastric inhibitory polypeptide modulates adiposity and fat oxidation under diminished insulin action

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12 December 2020

Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors

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12 December 2020

Role of gastrointestinal hormones in postprandial reduction of bone resorption

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Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors

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The many adaptations of bone

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Quantitative 3D analysis of the canal network in cortical bone by micro-computed tomography

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Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor.

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Postprandial bone turnover is independent of calories above 250 kcal

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Ovariectomy-induced bone loss varies among inbred strains of mice

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GLP-1 receptor agonists and the thyroid: C-cell effects in mice are mediated via the GLP-1 receptor and not associated with RET activation.

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Abnormal plasma glucose and insulin responses in heterozygous lean (ob/+) mice

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Interactions between microenvironment and cancer cells in two animal models of bone metastasis

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Quantitative X-ray imaging of rodent bone by Faxitron

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Glucose-dependent insulinotropic polypeptide receptor knockout mice have altered bone turnover

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Mouse pancreatic beta-cells exhibit preserved glucose competence after disruption of the glucagon-like peptide-1 receptor gene.

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12 December 2020

10.1007/S00198-014-2845-8

Identifiers

DOI

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12 March 2020

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