Pharmacokinetics, tissue distribution, excretion and plasma protein binding studies of wogonin in rats (Q87791732)

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17 March 2020

title

Pharmacokinetics, tissue distribution, excretion and plasma protein binding studies of wogonin in rats (English)

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17 March 2020

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Amer Talbi

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Di Zhao

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Qingwang Liu

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Junxiu Li

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Ali Fan

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Wei Yang

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Xing Han

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Xijing Chen

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17 March 2020

publication date

29 April 2014

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volume

19

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issue

5

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17 March 2020

page(s)

5538-5549

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Creative Commons Attribution 4.0 International

17 March 2020

copyright license

start time

29 April 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Inhibition of cyclooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from medicinal plants

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12 December 2020

Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi

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12 December 2020

Inhibition of TPA-induced cyclooxygenase-2 expression and skin inflammation in mice by wogonin, a plant flavone from Scutellaria radix

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12 December 2020

Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells

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12 December 2020

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease

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12 December 2020

Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1.

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12 December 2020

Quantitation of the flavonoid wogonin and its major metabolite wogonin-7 beta-D-glucuronide in rat plasma by liquid chromatography-tandem mass spectrometry

1 reference

12 December 2020

Simultaneous determination of glipizide and rosiglitazone unbound drug concentrations in plasma by equilibrium dialysis and liquid chromatography-tandem mass spectrometry

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12 December 2020

Therapeutic potential of wogonin: a naturally occurring flavonoid.

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12 December 2020

Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell

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12 December 2020

Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721.

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12 December 2020

Involvement of UDP-glucuronosyltransferases in the extensive liver and intestinal first-pass metabolism of flavonoid baicalein.

1 reference

12 December 2020

Anticancer effects of wogonin in both estrogen receptor-positive and -negative human breast cancer cell lines in vitro and in nude mice xenografts

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12 December 2020

Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis

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12 December 2020

Toxicological studies of wogonin in experimental animals

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12 December 2020

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

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12 December 2020

Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs.

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12 December 2020

Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects

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12 December 2020

Fusion Imaging: A Novel Staging Modality in Testis Cancer

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12 December 2020

Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63.

1 reference

12 December 2020

Developmental toxicity and genotoxicity studies of wogonin.

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12 December 2020

Impact of recovery on fraction unbound using equilibrium dialysis

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12 December 2020

Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae.

1 reference

12 December 2020

Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway

1 reference

12 December 2020

Wogonin induces apoptosis by activating the AMPK and p53 signaling pathways in human glioblastoma cells

1 reference

12 December 2020

Target-based selection of flavonoids for neurodegenerative disorders

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12 December 2020

Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein

1 reference

12 December 2020

Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells

1 reference

12 December 2020

LC-MS quantification and pharmacokinetics of the multi-constituents of Huangqin Tang in rat plasma after different single oral doses

1 reference

12 December 2020

Differences in pharmacokinetics and anti-inflammatory effects between decoction and maceration of Sanhuang Xiexin Tang in rats and mice

1 reference

12 December 2020

Comparative pharmacokinetics of baicalin, wogonoside, baicalein and wogonin in plasma after oral administration of pure baicalin, radix scutellariae and scutellariae-paeoniae couple extracts in normal and ulcerative colitis rats

1 reference

12 December 2020

Insights into drug discovery from natural medicines using reverse pharmacokinetics

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12 December 2020

10.3390/MOLECULES19055538

Identifiers

DOI

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17 March 2020

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17 March 2020

PubMed publication ID

24786691

1 reference