Targeting connexin 43 protects against the progression of experimental chronic kidney disease in mice (Q87924484)

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18 March 2020

title

Targeting connexin 43 protects against the progression of experimental chronic kidney disease in mice (English)

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chronic renal insufficiency

18 March 2020

main subject

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5

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18 March 2020

Carlo M Alfieri

6

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18 March 2020

author name string

Ahmed Abed

1

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18 March 2020

Julie Toubas

2

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18 March 2020

Panagiotis Kavvadas

3

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18 March 2020

Florence Authier

4

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18 March 2020

Jean-Jacques Boffa

7

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18 March 2020

Jean-Claude Dussaule

8

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18 March 2020

Christos Chatziantoniou

9

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18 March 2020

Christos E Chadjichristos

10

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18 March 2020

publication date

21 May 2014

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18 March 2020

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18 March 2020

volume

86

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issue

4

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page(s)

768-779

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Toward a unified theory of renal progression

18 March 2020

cites work

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Gap junctions and the connexin protein family

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Beyond the gap: functions of unpaired connexon channels

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Isoform composition of connexin channels determines selectivity among second messengers and uncharged molecules

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Connexin37 protects against atherosclerosis by regulating monocyte adhesion

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Reduced connexin43 expression limits neointima formation after balloon distension injury in hypercholesterolemic mice.

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7 January 2021

Alteration of connexin expression is an early signal for chronic kidney disease.

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7 January 2021

Cardiac malformation in neonatal mice lacking connexin43.

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Endothelial cell-specific knockout of connexin 43 causes hypotension and bradycardia in mice

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Connexin43-dependent mechanism modulates renin secretion and hypertension

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Vascular gap junctions in hypertension

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Targeting connexin 43 prevents platelet-derived growth factor-BB-induced phenotypic change in porcine coronary artery smooth muscle cells

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7 January 2021

Targeting connexin43 expression accelerates the rate of wound repair.

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7 January 2021

Blocking connexin43 expression reduces inflammation and improves functional recovery after spinal cord injury.

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7 January 2021

Connexin43 knockdown accelerates wound healing but inhibits mesenchymal transition after corneal endothelial injury in vivo

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7 January 2021

Discoidin domain receptor 1 is a major mediator of inflammation and fibrosis in obstructive nephropathy

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7 January 2021

Identification of two Sp1 phosphorylation sites for p42/p44 mitogen-activated protein kinases: their implication in vascular endothelial growth factor gene transcription

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7 January 2021

Human collagen Krox up-regulates type I collagen expression in normal and scleroderma fibroblasts through interaction with Sp1 and Sp3 transcription factors

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7 January 2021

The RenTg mice: a powerful tool to study renin-dependent chronic kidney disease

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7 January 2021

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

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7 January 2021

Connexin43 modulates neutrophil recruitment to the lung

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7 January 2021

TLR2 mediates gap junctional intercellular communication through connexin-43 in intestinal epithelial barrier injury

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7 January 2021

Altered pattern of vascular connexin expression in atherosclerotic plaques

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7 January 2021

Functional role of gap junctions in cytokine-induced leukocyte adhesion to endothelium in vivo

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7 January 2021

Time course of cytokine mRNA expression in kidneys of rats with unilateral ureteral obstruction

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7 January 2021

Cx43 contributes to TGF-beta signaling to regulate differentiation of cardiac fibroblasts into myofibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FKI.2014.108

7 January 2021

Upregulation and co-localization of connexin43 and cellular adhesion molecules in inflammatory renal disease

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7 January 2021

Up-regulation of connexin43 in glomerular podocytes in response to injury

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7 January 2021

Reduced connexin43 expression inhibits atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice

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7 January 2021

Interaction of connexins with protein partners in the control of channel turnover and gating.

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7 January 2021

C-terminal truncation of connexin43 changes number, size, and localization of cardiac gap junction plaques

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7 January 2021

Connexin 43 mediates spread of Ca2+-dependent proinflammatory responses in lung capillaries

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7 January 2021

Gap junction communication mediates transforming growth factor-beta activation and endothelial-induced mural cell differentiation

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7 January 2021

TGF-beta induces connexin43 gene expression in normal murine mammary gland epithelial cells via activation of p38 and PI3K/AKT signaling pathways

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7 January 2021

Gap junctions regulate extracellular signal-regulated kinase signaling to affect gene transcription

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7 January 2021

Reduced expression of Cx43 attenuates ventricular remodeling after myocardial infarction via impaired TGF-beta signaling

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7 January 2021

Cx43 mediates TGF-beta signaling through competitive Smads binding to microtubules

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7 January 2021

Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration.

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7 January 2021

Silencing the expression of connexin 43 decreases inflammation and joint destruction in experimental arthritis

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7 January 2021

Identifiers

DOI

10.1038/KI.2014.108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24850151%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference