Distinct WNT/β-catenin signaling activation in the serrated neoplasia pathway and the adenoma-carcinoma sequence of the colorectum (Q88070886)

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20 March 2020

title

Distinct WNT/β-catenin signaling activation in the serrated neoplasia pathway and the adenoma-carcinoma sequence of the colorectum (English)

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20 March 2020

3

Tsuyoshi Saito

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20 March 2020

1

Takashi Murakami

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author name string

Hiroyuki Mitomi

2

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20 March 2020

Michiko Takahashi

4

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Naoto Sakamoto

5

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Naoshi Fukui

6

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Takashi Yao

7

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Sumio Watanabe

8

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publication date

13 June 2014

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volume

28

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issue

1

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page(s)

146-158

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Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: concept of a 'fusion' pathway to colorectal cancer

20 March 2020

cites work

1 reference

12 December 2020

Molecular features of colorectal hyperplastic polyps and sessile serrated adenoma/polyps from Korea.

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12 December 2020

Frequent beta-catenin nuclear labeling in sessile serrated polyps of the colorectum with neoplastic potential

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Beta-catenin: a key mediator of Wnt signaling

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Clear cell variant of squamous cell carcinoma originating in the esophagus: report of a case with immunohistochemical and oncogenetic analyses

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Morphologic reappraisal of serrated colorectal polyps.

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APC mutations occur early during colorectal tumorigenesis

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The risk of metachronous neoplasia in patients with serrated adenoma

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Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps

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12 December 2020

Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation

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12 December 2020

Serrated polyps of the large intestine: a molecular study comparing sessile serrated adenomas and hyperplastic polyps.

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12 December 2020

Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer.

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12 December 2020

Hypermethylation and expression regulation of secreted frizzled-related protein genes in colorectal tumor

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12 December 2020

High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy.

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12 December 2020

Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas.

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12 December 2020

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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12 December 2020

Paneth cell differentiation in colonic epithelial neoplasms: evidence for the role of the Apc/beta-catenin/Tcf pathway.

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12 December 2020

Wnt signaling pathway is activated in right colon serrated polyps correlating to specific molecular form of β-catenin

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12 December 2020

Sessile serrated adenoma with early neoplastic progression: a clinicopathologic and molecular study

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12 December 2020

BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum

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12 December 2020

Sessile serrated adenomas and classical adenomas: an epigenetic perspective on premalignant neoplastic lesions of the gastrointestinal tract.

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12 December 2020

Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene

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12 December 2020

Serrated and non-serrated polyps of the colorectum: their prevalence in an unselected case series and correlation of BRAF mutation analysis with the diagnosis of sessile serrated adenoma.

1 reference

12 December 2020

Epigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instability

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12 December 2020

High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors

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12 December 2020

Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription

1 reference

12 December 2020

Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points

1 reference

12 December 2020

Proximal colon cancers and the serrated pathway: a systematic analysis of precursor histology and BRAF mutation status.

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12 December 2020

DNA stool test for colorectal cancer: hypermethylation of the secreted frizzled-related protein-1 gene.

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12 December 2020

10.1038/MODPATHOL.2014.41

Identifiers

DOI

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