Melatonin prevents Drp1-mediated mitochondrial fission in diabetic hearts through SIRT1-PGC1α pathway (Q88162418)

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21 March 2020

title

Melatonin prevents Drp1-mediated mitochondrial fission in diabetic hearts through SIRT1-PGC1α pathway (English)

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21 March 2020

1

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21 March 2020

Feng Fu

10

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21 March 2020

author name string

Na Feng

2

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21 March 2020

Daishi Tang

3

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21 March 2020

Jiahao Feng

4

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21 March 2020

Zeyang Li

5

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21 March 2020

Min Jia

6

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21 March 2020

Zhenhua Liu

7

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21 March 2020

Xiaoming Gu

8

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21 March 2020

Yuemin Wang

9

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21 March 2020

Jianming Pei

11

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21 March 2020

publication date

14 April 2018

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Journal of Pineal Research

21 March 2020

published in

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volume

65

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issue

2

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page(s)

e12491

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Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology

21 March 2020

cites work

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12 December 2020

Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species

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12 December 2020

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12 December 2020

NF-kappaB-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes.

1 reference

12 December 2020

Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes

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12 December 2020

Neurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol.

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12 December 2020

Mitochondrial dynamics in cardiovascular health and disease

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12 December 2020

Prevalence and control of diabetes in Chinese adults

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12 December 2020

Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms

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12 December 2020

Phosphorylation of DYNLT1 at serine 82 regulates microtubule stability and mitochondrial permeabilization in hypoxia

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12 December 2020

Mitochondrial dynamics--mitochondrial fission and fusion in human diseases

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12 December 2020

Drp1 loss-of-function reduces cardiomyocyte oxygen dependence protecting the heart from ischemia-reperfusion injury

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12 December 2020

Molecular mechanisms of diabetic cardiomyopathy.

1 reference

12 December 2020

Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats

1 reference

12 December 2020

Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients.

1 reference

12 December 2020

Melatonin receptor-mediated protection against myocardial ischemia/reperfusion injury: role of SIRT1.

1 reference

12 December 2020

Cardiac-specific ablation of ARNT leads to lipotoxicity and cardiomyopathy.

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12 December 2020

Drp1-mediated mitochondrial abnormalities link to synaptic injury in diabetes model

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12 December 2020

Mitochondrial metabolism and the control of vascular smooth muscle cell proliferation

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12 December 2020

Melatonin: Physiological effects in humans

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12 December 2020

SIRT1 suppresses cardiomyocyte apoptosis in diabetic cardiomyopathy: An insight into endoplasmic reticulum stress response mechanism

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12 December 2020

Melatonin reverses H2 O2 -induced premature senescence in mesenchymal stem cells via the SIRT1-dependent pathway.

1 reference

12 December 2020

Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice

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12 December 2020

Redox Homeostasis and Mitochondrial Dynamics.

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12 December 2020

Reduced silent information regulator 1 signaling exacerbates myocardial ischemia-reperfusion injury in type 2 diabetic rats and the protective effect of melatonin.

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12 December 2020

Role of toll-like receptor 4 in melatonin-induced cardioprotection

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12 December 2020

SIRT1 protects against myocardial ischemia-reperfusion injury via activating eNOS in diabetic rats

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12 December 2020

Therapeutic inhibition of mitochondrial reactive oxygen species with mito-TEMPO reduces diabetic cardiomyopathy

1 reference

12 December 2020

Melatonin prevents abnormal mitochondrial dynamics resulting from the neurotoxicity of cadmium by blocking calcium-dependent translocation of Drp1 to the mitochondria

1 reference

12 December 2020

Melatonin enhances mitophagy and mitochondrial biogenesis in rats with carbon tetrachloride-induced liver fibrosis.

1 reference

12 December 2020

MicroRNA-630 suppresses tumor metastasis through the TGF-β- miR-630-Slug signaling pathway and correlates inversely with poor prognosis in hepatocellular carcinoma

1 reference

12 December 2020

DJ-1 protects the heart against ischemia-reperfusion injury by regulating mitochondrial fission

1 reference

12 December 2020

Melatonin prevents the dynamin-related protein 1-dependent mitochondrial fission and oxidative insult in the cortical neurons after 1-methyl-4-phenylpyridinium treatment

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12 December 2020

Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes

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12 December 2020

Elevated heart rate and nondipping heart rate as potential targets for melatonin: a review

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12 December 2020

Mitochondrial Peroxiredoxin-3 protects against hyperglycemia induced myocardial damage in Diabetic cardiomyopathy

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12 December 2020

Mitochondrial dysfunction and its impact on diabetic heart

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12 December 2020

Melatonin prevents acute kidney injury in severely burned rats via the activation of SIRT1.

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12 December 2020

High glucose concentration abrogates sevoflurane post-conditioning cardioprotection by advancing mitochondrial fission but dynamin-related protein 1 inhibitor restores these effects

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12 December 2020

Metformin Suppresses Diabetes-Accelerated Atherosclerosis via the Inhibition of Drp1-Mediated Mitochondrial Fission

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12 December 2020

A novel fission-independent role of dynamin-related protein 1 in cardiac mitochondrial respiration

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12 December 2020

Novel protective role of the circadian nuclear receptor retinoic acid-related orphan receptor-α in diabetic cardiomyopathy.

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12 December 2020

Sirtuin 1 protects the aging heart from contractile dysfunction mediated through the inhibition of endoplasmic reticulum stress-mediated apoptosis in cardiac-specific Sirtuin 1 knockout mouse model.

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12 December 2020

Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics

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12 December 2020

Melatonin regulates lipid metabolism in porcine oocytes

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12 December 2020

Inhibition of dynamin-related protein 1 protects against myocardial ischemia-reperfusion injury in diabetic mice.

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12 December 2020

Molecular regulation of mitochondrial dynamics in cardiac disease

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12 December 2020

The role of SIRT1 in diabetic cardiomyopathy

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12 December 2020

Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission-VDAC1-HK2-mPTP-mitophagy axis

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12 December 2020

Melatonin protects against diabetic cardiomyopathy through Mst1/Sirt3 signaling

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12 December 2020

Melatonin protects against the pathological cardiac hypertrophy induced by transverse aortic constriction through activating PGC-1β: In vivo and in vitro studies.

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12 December 2020

Melatonin suppresses platelet activation and function against cardiac ischemia/reperfusion injury via PPARγ/FUNDC1/mitophagy pathways.

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12 December 2020

Resveratrol alleviates diabetic cardiomyopathy in rats by improving mitochondrial function through PGC-1α deacetylation

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12 December 2020

SIRT1 Activation by Resveratrol Alleviates Cardiac Dysfunction via Mitochondrial Regulation in Diabetic Cardiomyopathy Mice.

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12 December 2020

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12 December 2020

Melatonin prevents endothelial cell pyroptosis via regulation of long noncoding RNA MEG3/miR-223/NLRP3 axis

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12 December 2020

Melatonin: A Versatile Protector against Oxidative DNA Damage

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12 December 2020

Identifiers

DOI

10.1111/JPI.12491

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29575122%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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21 March 2020

PubMed publication ID

29575122

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