KRAS A146 (Q88412581)

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genetic variant

A146

Language	Label	Description	Also known as
English	KRAS A146	genetic variant	A146

Statements

biological variant of

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/2979

negative therapeutic predictor for

cetuximab / chemotherapy combination therapy

determination method

CIViC evidence level B

CIViC 3-star trust rating

medical condition treated

colorectal cancer

statement disputed by

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/evidence/3939

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

Identifiers

CIViC variant ID

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/2979

Sitelinks

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