Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms (Q89008046)

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30 March 2020

title

Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms (English)

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2

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Simon C Watkins

6

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ORCID Public Data File 2021

author name string

Laurent Muller

1

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Chang-Sook Hong

3

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30 March 2020

Michael I Nishimura

4

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Edwin K Jackson

5

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30 March 2020

Theresa L Whiteside

7

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publication date

19 July 2017

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volume

6

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issue

8

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30 March 2020

page(s)

e1261243

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Fas ligand-positive membranous vesicles isolated from sera of patients with oral cancer induce apoptosis of activated T lymphocytes.

30 March 2020

cites work

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12 December 2020

Identifying mRNA, microRNA and protein profiles of melanoma exosomes

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Tetraspanins in extracellular vesicle formation and function

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Immunomodulatory and neuroprotective effects of inosine

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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

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CD97 promotes gastric cancer cell proliferation and invasion through exosome-mediated MAPK signaling pathway

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Routes and mechanisms of extracellular vesicle uptake

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Immune modulation of T-cell and NK (natural killer) cell activities by TEXs (tumour-derived exosomes)

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12 December 2020

Exosomes and tumor-mediated immune suppression

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12 December 2020

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Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets

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12 December 2020

Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1.

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12 December 2020

Adenosine production by human B cells and B cell-mediated suppression of activated T cells

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12 December 2020

Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells

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12 December 2020

The calcium feedback loop and T cell activation: how cytoskeleton networks control intracellular calcium flux

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12 December 2020

Isolation of biologically active and morphologically intact exosomes from plasma of patients with cancer

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12 December 2020

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

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12 December 2020

Cellular internalization of exosomes occurs through phagocytosis

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12 December 2020

Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment

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12 December 2020

Biogenesis and secretion of exosomes.

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Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg).

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Association of citrullinated proteins with synovial exosomes

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Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells

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12 December 2020

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Exosomes/microvesicles: mediators of cancer-associated immunosuppressive microenvironments

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Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

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12 December 2020

Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines.

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Phenotypic and functional characteristics of CD39high human regulatory B cells (Breg).

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Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

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Formation and role of exosomes in cancer

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Cancer exosomes and NKG2D receptor-ligand interactions: impairing NKG2D-mediated cytotoxicity and anti-tumour immune surveillance.

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12 December 2020

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

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12 December 2020

Immunoregulatory activity of adenosine and its role in human cancer progression

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12 December 2020

Tumor-derived microvesicles promote regulatory T cell expansion and induce apoptosis in tumor-reactive activated CD8+ T lymphocytes

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12 December 2020

Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles.

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12 December 2020

The adenosine metabolite inosine is a functional agonist of the adenosine A2A receptor with a unique signaling bias.

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12 December 2020

10.1080/2162402X.2016.1261243

Identifiers

DOI

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30 March 2020

PubMed publication ID

28919985

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