The Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer's (Q89334340)

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scientific article published on 08 March 2018

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English	The Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer's	scientific article published on 08 March 2018

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scholarly article

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3 April 2020

The Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer's disease, including a placebo-treated noncarrier cohort (English)

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3 April 2020

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Alzheimer's disease

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author name string

Pierre N Tariot

1

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3 April 2020

Francisco Lopera

2

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3 April 2020

Jessica B Langbaum

3

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3 April 2020

Ronald G Thomas

4

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Suzanne Hendrix

5

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3 April 2020

Lon S Schneider

6

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3 April 2020

Silvia Rios-Romenets

7

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Margarita Giraldo

8

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Natalia Acosta

9

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Carlos Tobon

10

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3 April 2020

Claudia Ramos

11

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3 April 2020

Alejandro Espinosa

12

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3 April 2020

William Cho

13

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3 April 2020

Michael Ward

14

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3 April 2020

David Clayton

15

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3 April 2020

Michael Friesenhahn

16

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3 April 2020

Howard Mackey

17

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3 April 2020

Lee Honigberg

18

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3 April 2020

Sandra Sanabria Bohorquez

19

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3 April 2020

Kewei Chen

20

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3 April 2020

Trisha Walsh

21

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3 April 2020

Carolyn Langlois

22

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3 April 2020

Eric M Reiman

23

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3 April 2020

Alzheimer's Prevention Initiative

24

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3 April 2020

publication date

8 March 2018

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3 April 2020

Alzheimer's & dementia (New York, N. Y.)

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3 April 2020

4

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3 April 2020

150-160

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3 April 2020

Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported.

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The amyloid hypothesis of Alzheimer's disease at 25 years

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Homozygosity of the autosomal dominant Alzheimer disease presenilin 1 E280A mutation

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E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles

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Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation

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Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study

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Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease

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based on heuristic

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based on heuristic

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10.1016/J.TRCI.2018.02.002

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3 April 2020

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3 April 2020

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3 April 2020

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