HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers (Q90340957)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30024859%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

title

HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers (English)

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1

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Guinevere Q Lee

2

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Xiaoming Sun

3

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David M. Margolis

17

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21

Daniel R Kuritzkes

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author name string

Behzad Etemad

4

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Layla M Aboukhater

5

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Zixin Hu

6

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Zabrina L Brumme

7

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Evgenia Aga

8

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Ronald J Bosch

9

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Ying Wen

10

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Golnaz Namazi

11

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Ce Gao

12

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Edward P Acosta

13

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Rajesh T Gandhi

14

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Jeffrey M Jacobson

15

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Daniel Skiest

16

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Ronald Mitsuyasu

18

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Paul Volberding

19

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Elizabeth Connick

20

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Michael M Lederman

22

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Xu G Yu

23

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Mathias Lichterfeld

24

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Jonathan Z Li

25

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publication date

20 August 2018

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Journal of Clinical Investigation

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published in

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volume

128

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page(s)

4074-4085

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issue

9

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A second origin of DNA plus-strand synthesis is required for optimal human immunodeficiency virus replication

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cites work

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12 December 2020

Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

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Detecting hypermutations in viral sequences with an emphasis on G --> A hypermutation

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Analysis of plus-strand primer selection, removal, and reutilization by retroviral reverse transcriptases.

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Human immunodeficiency virus reverse transcriptase and protease sequence database

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HIV-1 DNA burden dynamics in CD4 T cells and monocytes in patients undergoing a transient therapy interruption

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Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis

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Effect of polypurine tract (PPT) mutations on human immunodeficiency virus type 1 replication: a virus with a completely randomized PPT retains low infectivity

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Evidence that intermittent structured treatment interruption, but not immunization with ALVAC-HIV vCP1452, promotes host control of HIV replication: the results of AIDS Clinical Trials Group 5068

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Rationale and uses of a public HIV drug-resistance database

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Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolution

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Interruption of antiretroviral treatment in HIV-infected patients with preserved immune function is associated with a low rate of clinical progression: a prospective study by AIDS Clinical Trials Group 5170.

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12 December 2020

Frequent polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase

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Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

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12 December 2020

Antiretroviral therapy in acute and recent HIV infection: a prospective multicenter stratified trial of intentionally interrupted treatment

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Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection

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AIDS clinical trials group 5197: a placebo-controlled trial of immunization of HIV-1-infected persons with a replication-deficient adenovirus type 5 vaccine expressing the HIV-1 core protein

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Selection of reliable reference genes for quantitative real-time PCR in human T cells and neutrophils

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Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy

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Immune and viral correlates of "secondary viral control" after treatment interruption in chronically HIV-1 infected patients

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12 December 2020

Immunovirologic control 24 months after interruption of antiretroviral therapy initiated close to HIV seroconversion.

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12 December 2020

HIV-1 control after transient antiretroviral treatment initiated in primary infection: role of patient characteristics and effect of therapy.

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12 December 2020

Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1.

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12 December 2020

Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study

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12 December 2020

Duration of HIV-1 viral suppression on cessation of antiretroviral therapy in primary infection correlates with time on therapy

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12 December 2020

Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure.

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12 December 2020

HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

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12 December 2020

HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection

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Antiretroviral-free HIV-1 remission and viral rebound after allogeneic stem cell transplantation: report of 2 cases

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12 December 2020

Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1

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12 December 2020

HIV-1 DNA predicts disease progression and post-treatment virological control

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12 December 2020

Post-treatment control of HIV infection

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12 December 2020

How often does treatment of primary HIV lead to post-treatment control?

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12 December 2020

A low HIV-DNA level in peripheral blood mononuclear cells at antiretroviral treatment interruption predicts a higher probability of maintaining viral control

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12 December 2020

The size of the expressed HIV reservoir predicts timing of viral rebound after treatment interruption

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12 December 2020

Treatment interruption in chronically HIV-infected patients with an ultralow HIV reservoir

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12 December 2020

HIV-1 virological remission lasting more than 12 years after interruption of early antiretroviral therapy in a perinatally infected teenager enrolled in the French ANRS EPF-CO10 paediatric cohort: a case report

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12 December 2020

Post-Treatment Controllers: Role in HIV "Cure" Research

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12 December 2020

Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV

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12 December 2020

Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy

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12 December 2020

Defective proviruses rapidly accumulate during acute HIV-1 infection

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12 December 2020

Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA.

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12 December 2020

Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir

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12 December 2020

Proliferation of latently infected CD4+ T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics

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12 December 2020

Defective HIV-1 Proviruses Are Expressed and Can Be Recognized by Cytotoxic T Lymphocytes, which Shape the Proviral Landscape.

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12 December 2020

Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART.

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12 December 2020

Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells

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12 December 2020

Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants.

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12 December 2020

A randomized controlled safety/efficacy trial of therapeutic vaccination in HIV-infected individuals who initiated antiretroviral therapy early in infection.

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12 December 2020

Effect of analytical treatment interruption and reinitiation of antiretroviral therapy on HIV reservoirs and immunologic parameters in infected individuals.

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12 December 2020

Post treatment controllers after treatment interruption in chronically HIV infected patients.

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12 December 2020

Clonal CD4+ T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation.

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12 December 2020

Identifiers

DOI

10.1172/JCI120549

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