Solute carrier family 5 member 1 (Q904241)

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mammalian protein found in Homo sapiens

• solute carrier family 5 (sodium/glucose cotransporter), member 1
• Na+/glucose cotransporter 1
• high affinity sodium-glucose cotransporter
• sodium/glucose cotransporter 1
• SLC5A1

edit

Language	Label	Description	Also known as
English	Solute carrier family 5 member 1	mammalian protein found in Homo sapiens	solute carrier family 5 (sodium/glucose cotransporter), member 1 Na+/glucose cotransporter 1 high affinity sodium-glucose cotransporter sodium/glucose cotransporter 1 SLC5A1

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13866

part of

sodium-solute symporter

2 references

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13866

Transporter Classification Database ID

2.A.21.3.1

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

Sodium/glucose symporter superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13866

Sodium/solute symporter, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13866

encoded by

SLC5A1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13866

molecular function

transporter activity

determination method

IEA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

IEA

protein binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

Survival of cancer cells is maintained by EGFR independent of its kinase activity

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IPI

symporter activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

glucose:sodium symporter activity

determination method

IEA

IDA

TAS

3 references

retrieved

26 September 2017

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

TAS

retrieved

26 September 2017

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

IEA

retrieved

26 September 2017

stated in

Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

IDA

glucose:sodium symporter activity

determination method

IBA

IDA

IEA

TAS

5 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

retrieved

8 April 2019

stated in

The human gene of a protein that modifies Na(+)-D-glucose co-transport

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IDA

retrieved

8 April 2019

stated in

Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IBA

transmembrane transporter activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

cell component

integral component of membrane

determination method

IEA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

IEA

membrane

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

cell-cell junction

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

plasma membrane

determination method

TAS

1 reference

retrieved

26 September 2017

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

TAS

integral component of plasma membrane

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

TAS

brush border membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

apical plasma membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

extracellular exosome

determination method

IDA

2 references

retrieved

26 September 2017

stated in

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

IDA

retrieved

26 September 2017

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

IDA

plasma membrane

determination method

IBA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

TAS

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IBA

integral component of membrane

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IBA

extracellular exosome

determination method

HDA

1 reference

retrieved

8 April 2019

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

HDA

biological process

glucose transmembrane transport

determination method

IEA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

IEA

sodium ion transport

determination method

IEA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

IEA

ion transport

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

carbohydrate transport

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

transmembrane transport

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

intestinal D-glucose absorption

determination method

IBA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

IBA

intestinal hexose absorption

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

TAS

transport

determination method

IEA

2 references

retrieved

26 September 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

IEA

retrieved

26 September 2017

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13866&geneProductId=UniProtKB:P13866

determination method

IEA

sodium ion transport

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IBA

glucose transmembrane transport

determination method

IDA

IMP

2 references

retrieved

8 April 2019

stated in

Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IMP

retrieved

8 April 2019

stated in

The human gene of a protein that modifies Na(+)-D-glucose co-transport

GOA

curator

UniProt

UniProt protein ID

P13866

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13866

determination method

IDA

physically interacts with

canagliflozin

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4582

language of work or name

English

retrieved

17 August 2016

dapagliflozin

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4594

language of work or name

English

retrieved

17 August 2016

empagliflozin

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4754

language of work or name

English

retrieved

17 August 2016

sergliflozin etabonate

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4587

language of work or name

English

retrieved

17 August 2016

Gene Atlas image

PBB GE SLC5A1 206628 at fs.png
732 × 530; 11 KB

0 references

has part(s)

sodium/solute symporter, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13866

Identifiers

MeSH descriptor ID

D051269

0 references

RefSeq protein ID

NP_000334

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

6523

NP_001243243

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

6523

XP_011528633

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

6523

UniProt protein ID

P13866

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13866

Ensembl protein ID

ENSP00000266088

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000266088

ENSP00000444898

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000444898

Freebase ID

/m/02kfsf2

0 references

Microsoft Academic ID

2780655865

0 references

Transporter Classification Database ID

2.A.21.3.1

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

UMLS CUI

C0248805

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(8 entries)

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• dewiki Natrium/Glucose-Cotransporter 1
• enwiki Sodium/glucose cotransporter 1
• fawiki SLC5A1
• frwiki Cotransporteur sodium-glucose 1
• itwiki SGLT1
• svwiki SGLT1
• ttwiki SLC5A1
• ukwiki SLC5A1

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q904241&oldid=2022902749"