Verdinexor (KPT-335), a Selective Inhibitor of Nuclear Export, Reduces Respiratory Syncytial Virus Replication In Vitro (Q90434268)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

title

Verdinexor (KPT-335), a Selective Inhibitor of Nuclear Export, Reduces Respiratory Syncytial Virus Replication In Vitro (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

5

Jasmina M Luczo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

2

Cynthia Mathew

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

3

Jennifer Pickens

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

author name string

Patricia A Jorquera

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Colin Williams

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Sharon Tamir

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Reena Ghildyal

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

publication date

5 February 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

volume

93

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

13 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6364025/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Preparation and characterization of monoclonal antibodies directed against five structural components of human respiratory syncytial virus subgroup B.

1 reference

12 December 2020

Ribavirin for respiratory syncytial virus infection

1 reference

12 December 2020

Comparison of respiratory syncytial virus humoral immunity and response to infection in young and elderly adults

1 reference

12 December 2020

A comparison of the activity, sequence specificity, and CRM1-dependence of different nuclear export signals

1 reference

12 December 2020

Transcription factor-kappa B (NF-kappa B) and renal disease.

1 reference

12 December 2020

Respiratory syncytial virus matrix protein associates with nucleocapsids in infected cells

1 reference

12 December 2020

Risk factors for severe respiratory syncytial virus infection in infants.

1 reference

12 December 2020

Sorting of the respiratory syncytial virus matrix protein into detergent-resistant structures is dependent on cell-surface expression of the glycoproteins

1 reference

12 December 2020

The matrix protein of Human respiratory syncytial virus localises to the nucleus of infected cells and inhibits transcription

1 reference

12 December 2020

Association of matrix protein of respiratory syncytial virus with the host cell membrane of infected cells

1 reference

12 December 2020

Population-based surveillance for hospitalizations associated with respiratory syncytial virus, influenza virus, and parainfluenza viruses among young children

1 reference

12 December 2020

Respiratory syncytial virus infection in elderly and high-risk adults

1 reference

12 December 2020

Interaction between the respiratory syncytial virus G glycoprotein cytoplasmic domain and the matrix protein

1 reference

12 December 2020

Nuclear import of the respiratory syncytial virus matrix protein is mediated by importin beta1 independent of importin alpha

1 reference

12 December 2020

Association of respiratory syncytial virus M protein with viral nucleocapsids is mediated by the M2-1 protein

1 reference

12 December 2020

Epidemiologic, experimental, and clinical links between respiratory syncytial virus infection and asthma

1 reference

12 December 2020

The respiratory syncytial virus matrix protein possesses a Crm1-mediated nuclear export mechanism

1 reference

12 December 2020

Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication

1 reference

12 December 2020

Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis

1 reference

12 December 2020

Protein-protein interactions in RSV assembly: potential targets for attenuating RSV strains.

1 reference

12 December 2020

Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia

1 reference

12 December 2020

NESdb: a database of NES-containing CRM1 cargoes

1 reference

12 December 2020

Novel selective inhibitors of nuclear export CRM1 antagonists for therapy in mantle cell lymphoma

1 reference

12 December 2020

The cost effectiveness of palivizumab in congenital heart disease: a review of the current evidence.

1 reference

12 December 2020

Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1

1 reference

12 December 2020

KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia.

1 reference

12 December 2020

The comparative genomics of human respiratory syncytial virus subgroups A and B: genetic variability and molecular evolutionary dynamics

1 reference

12 December 2020

Preclinical evaluation of the novel, orally bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in spontaneous canine cancer: results of a phase I study

1 reference

12 December 2020

The Thr205 phosphorylation site within respiratory syncytial virus matrix (M) protein modulates M oligomerization and virus production

1 reference

12 December 2020

Verdinexor, a novel selective inhibitor of nuclear export, reduces influenza a virus replication in vitro and in vivo.

1 reference

12 December 2020

Biologic activity of the novel orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 against canine melanoma cell lines

1 reference

12 December 2020

KPT-330 inhibitor of XPO1-mediated nuclear export has anti-proliferative activity in hepatocellular carcinoma

1 reference

12 December 2020

XPO1/CRM1-selective inhibitors of nuclear export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa).

1 reference

12 December 2020

Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma

1 reference

12 December 2020

KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin [corrected] in prostate cancer models.

1 reference

12 December 2020

The Regulation of NF-κB Subunits by Phosphorylation

1 reference

12 December 2020

Quantification of RSV Infectious Particles by Plaque Assay and Immunostaining Assay.

1 reference

12 December 2020

The Respiratory Syncytial Virus Phosphoprotein, Matrix Protein, and Fusion Protein Carboxy-Terminal Domain Drive Efficient Filamentous Virus-Like Particle Formation

1 reference

12 December 2020

Rhinovirus 16 2A Protease Affects Nuclear Localization of 3CD during Infection

1 reference

12 December 2020

Antiviral Efficacy of Verdinexor In Vivo in Two Animal Models of Influenza A Virus Infection

1 reference

12 December 2020

Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells

1 reference

12 December 2020

Respiratory syncytial virus: prospects for new and emerging therapeutics

1 reference

12 December 2020

CRM1 Inhibitors for Antiviral Therapy

1 reference

12 December 2020

ICTV Virus Taxonomy Profile: Pneumoviridae

1 reference

12 December 2020

Verdinexor Targeting of CRM1 is a Promising Therapeutic Approach against RSV and Influenza Viruses

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.01684-18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541831%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

1 reference