Emerin (Q905741)

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mammalian protein found in Homo sapiens
  • LEM domain containing 5
  • uniprot:P50402
  • EMD
  • emerin
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Language Label Description Also known as
English
Emerin
mammalian protein found in Homo sapiens
  • LEM domain containing 5
  • uniprot:P50402
  • EMD
  • emerin

Statements

image
Protein EMD PDB 1jei.png
667 × 433; 99 KB
0 references
molecular function
protein binding
determination method
IPI
17 references
retrieved
1 January 2018
stated in
Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle
GOA
curator
UniProt
UniProt protein ID
P50402
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus
GOA
curator
UniProt
UniProt protein ID
P50402
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane
GOA
curator
UniProt
UniProt protein ID
P50402
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo
GOA
curator
UniProt
UniProt protein ID
P50402
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
Emerin-prelamin A interplay in human fibroblasts
GOA
curator
UniProt
UniProt protein ID
P50402
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
Samp1 is functionally associated with the LINC complex and A-type lamina networks
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
A human protein-protein interaction network: a resource for annotating the proteome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
retrieved
1 January 2018
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IPI
cell component
nuclear envelope
determination method
IDA
IEA
IMP
TAS
8 references
retrieved
17 October 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50402&geneProductId=UniProtKB:P50402
determination method
TAS
retrieved
17 October 2017
stated in
Emerin deficiency at the nuclear membrane in patients with Emery-Dreifuss muscular dystrophy
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50402&geneProductId=UniProtKB:P50402
determination method
TAS
retrieved
17 October 2017
stated in
Samp1 is functionally associated with the LINC complex and A-type lamina networks
GOA
curator
UniProt
UniProt protein ID
P50402
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50402&geneProductId=UniProtKB:P50402
determination method
IMP
retrieved
17 October 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50402&geneProductId=UniProtKB:P50402
determination method
IEA
retrieved
17 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50402&geneProductId=UniProtKB:P50402
determination method
IEA
retrieved
17 October 2017
stated in
GOA
curator
LifeDB
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50402&geneProductId=UniProtKB:P50402
determination method
IDA
retrieved
17 October 2017
stated in
The effect of the lamin A and its mutants on nuclear structure, cell proliferation, protein stability, and mobility in embryonic cells
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50402&geneProductId=UniProtKB:P50402
determination method
IDA
retrieved
17 October 2017
stated in
The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50402&geneProductId=UniProtKB:P50402
determination method
IDA
nuclear envelope
determination method
IBA
IDA
IEA
IMP
TAS
9 references
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
TAS
retrieved
1 January 2018
stated in
Emerin deficiency at the nuclear membrane in patients with Emery-Dreifuss muscular dystrophy
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
TAS
retrieved
1 January 2018
stated in
Samp1 is functionally associated with the LINC complex and A-type lamina networks
GOA
curator
UniProt
UniProt protein ID
P50402
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IMP
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
LifeDB
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IDA
retrieved
1 January 2018
stated in
The effect of the lamin A and its mutants on nuclear structure, cell proliferation, protein stability, and mobility in embryonic cells
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IDA
retrieved
1 January 2018
stated in
The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50402
determination method
IBA
biological process
Gene Atlas image
PBB GE EMD 209477 at fs.png
732 × 530; 12 KB
0 references

Identifiers

Freebase ID
/m/0269cx6
0 references
 
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