TNFAIP8 promotes the proliferation and cisplatin chemoresistance of non-small cell lung cancer through MDM2/p53 pathway (Q90667959)

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15 April 2020

title

TNFAIP8 promotes the proliferation and cisplatin chemoresistance of non-small cell lung cancer through MDM2/p53 pathway (English)

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Ying Xing

1

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Yuechao Liu

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Tianbo Liu

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Qingwei Meng

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Hailing Lu

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Wei Liu

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Jing Hu

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Chunhong Li

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Mengru Cao

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Shi Yan

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Jian Huang

11

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Ting Wang

12

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Li Cai

13

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publication date

31 July 2018

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Cell Communication and Signaling

15 April 2020

published in

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volume

16

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issue

1

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page(s)

43

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Creative Commons Attribution 4.0 International

15 April 2020

copyright license

start time

31 July 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

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11 June 2022

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inferred from PubMed Central ID database lookup

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Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes

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Nuclear factor-kappa B-inducible death effector domain-containing protein suppresses tumor necrosis factor-mediated apoptosis by inhibiting caspase-8 activity

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DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis

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p53 interacts with hRAD51 and hRAD54, and directly modulates homologous recombination

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Mislocalization of membrane proteins associated with multidrug resistance in cisplatin-resistant cancer cell lines

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Cisplatin: mode of cytotoxic action and molecular basis of resistance

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Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

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Expression of SCC-S2, an antiapoptotic molecule, correlates with enhanced proliferation and tumorigenicity of MDA-MB 435 cells

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Negative regulation of dE2F1 by cyclin-dependent kinases controls cell cycle timing

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Differential expression of VASP in normal lung tissue and lung adenocarcinomas

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p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene

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Differential expression of drug-resistance-related genes between sensitive and resistant blasts in acute myeloid leukemia

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Transcriptional targets of p53 that regulate cellular proliferation.

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Chemotherapy and survival benefit in elderly patients with advanced non-small-cell lung cancer

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12 December 2020

TNFAIP8 overexpression: clinical relevance to esophageal squamous cell carcinoma

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SCC-S2 is overexpressed in colon cancers and regulates cell proliferation.

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Tissue platinum concentration and tumor response in non-small-cell lung cancer

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12 December 2020

The significance of TNFAIP8 in prostate cancer response to radiation and docetaxel and disease recurrence

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12 December 2020

The MDM2-p53 pathway revisited

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12 December 2020

TNFAIP8 as a predictor of metastasis and a novel prognostic biomarker in patients with epithelial ovarian cancer

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12 December 2020

Correlation of TNFAIP8 overexpression with the proliferation, metastasis, and disease-free survival in endometrial cancer.

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12 December 2020

TNFAIP8 overexpression is associated with lymph node metastasis and poor prognosis in intestinal-type gastric adenocarcinoma

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12 December 2020

TNFAIP8 overexpression is associated with platinum resistance in epithelial ovarian cancers with optimal cytoreduction

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12 December 2020

Cisplatin in cancer therapy: molecular mechanisms of action

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12 December 2020

Pharmacogenetics of the DNA repair pathways in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy

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12 December 2020

Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers

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12 December 2020

p53 in survival, death and metabolic health: a lifeguard with a licence to kill

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12 December 2020

Tumor-suppressive miR-99a inhibits cell proliferation via targeting of TNFAIP8 in osteosarcoma cells

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Cancer treatment and survivorship statistics, 2016.

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12 December 2020

Association between the expression levels of tumor necrosis factor-α-induced protein 8 and the prognosis of patients with gastric adenocarcinoma

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12 December 2020

The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression

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12 December 2020

Cancer Statistics, 2017.

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12 December 2020

Overexpression of TNFAIP8 is associated with tumor aggressiveness and poor prognosis in patients with invasive ductal breast carcinoma

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12 December 2020

MicroRNA-9 inhibits the gastric cancer cell proliferation by targeting TNFAIP8.

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12 December 2020

TNFAIP8 interacts with LATS1 and promotes aggressiveness through regulation of Hippo pathway in hepatocellular carcinoma

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12 December 2020

Contribution of genetic factors to platinum-based chemotherapy sensitivity and prognosis of non-small cell lung cancer

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12 December 2020

Putting p53 in Context

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12 December 2020

10.1186/S12964-018-0254-X

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30064446%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

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15 April 2020

PubMed publication ID

30064446

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