Serum response factor (Q907394)

http://www.ebi.ac.uk/interpro/protein/P11831

Transcription factor, MADS-box, protein family

1 reference

based on heuristic

inferred from protein domain or family

MADS SRF-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein dimerization activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

RNA polymerase II general transcription initiation factor activity

1 reference

10 September 2018

Structural and functional analysis of domains mediating interaction between the bagpipe homologue, Nkx3.1 and serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

transcription factor binding

IMP

protein homodimerization activity

IPI

1 reference

8 April 2019

Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

10 references

8 April 2019

Functional interactions between the Forkhead transcription factor FOXK1 and the MADS-box protein SRF.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Structural and functional analysis of domains mediating interaction between the bagpipe homologue, Nkx3.1 and serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Olfactomedin 2, a novel regulator for transforming growth factor-β-induced smooth muscle differentiation of human embryonic stem cell-derived mesenchymal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

The LIM protein leupaxin is enriched in smooth muscle and functions as an serum response factor cofactor to induce smooth muscle cell gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Megakaryoblastic Leukemia-1/2, a Transcriptional Co-activator of Serum Response Factor, Is Required for Skeletal Myogenic Differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Interaction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Potentiation of serum response factor activity by a family of myocardin-related transcription factors

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Megakaryoblastic Leukemia-1/2, a Transcriptional Co-activator of Serum Response Factor, Is Required for Skeletal Myogenic Differentiation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

sequence-specific DNA binding

IPI

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

chromatin DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

DNA-binding transcription factor activity, RNA polymerase II-specific

histone deacetylase binding

ISM

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

transcription factor binding

3 references

8 April 2019

Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Structural and functional analysis of domains mediating interaction between the bagpipe homologue, Nkx3.1 and serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

RNA polymerase II-specific DNA-binding transcription factor binding

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

DNA-binding transcription factor activity, RNA polymerase II-specific

5 references

1 January 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

1 January 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

DNA-binding transcription activator activity, RNA polymerase II-specific

IBA

3 references

DNA-binding transcription factor activity

3 references

8 April 2019

Structural and functional analysis of domains mediating interaction between the bagpipe homologue, Nkx3.1 and serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

DNA-binding transcription factor activity, RNA polymerase II-specific

4 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

5 June 2018

Synergism in ternary complex formation between the dimeric glycoprotein p67SRF, polypeptide p62TCF and the c-fos serum response element

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Synergism in ternary complex formation between the dimeric glycoprotein p67SRF, polypeptide p62TCF and the c-fos serum response element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

dorsal aorta morphogenesis

IBA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

bronchus cartilage development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

lung smooth muscle development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

regulation of water loss via skin

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

transcription by RNA polymerase II

1 reference

8 April 2019

Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

stress fiber assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

cardiac myofibril assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

Protein kinase C delta blocks immediate-early gene expression in senescent cells by inactivating serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

regulation of cell adhesion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

neuron projection development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

morphogenesis of an epithelial sheet

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

positive regulation of filopodium assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

primitive streak formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

cellular response to glucose stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

negative regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

heart trabecula formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

actin filament organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

angiogenesis involved in wound healing

1 reference

8 April 2019

Serum response factor is a critical requirement for VEGF signaling in endothelial cells and VEGF-induced angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

Serum response factor binding sites differ in three human cell types

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

in utero embryonic development

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

positive regulation of cell differentiation

1 reference

8 April 2019

HOP/NECC1, a novel regulator of mouse trophoblast differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

branching involved in blood vessel morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

positive regulation of axon extension

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

positive regulation of smooth muscle contraction

1 reference

8 April 2019

Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

trachea cartilage development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

response to toxic substance

1 reference

8 April 2019

Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

positive regulation of transcription by glucose

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

regulation of smooth muscle cell differentiation

1 reference

8 April 2019

Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

epithelial structure maintenance

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

positive regulation of DNA-binding transcription factor activity

1 reference

10 September 2018

SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

epithelial cell-cell adhesion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

positive regulation of transcription initiation from RNA polymerase II promoter

1 reference

8 April 2019

Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

eyelid development in camera-type eye

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

thyroid gland development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

negative regulation of amyloid-beta clearance

1 reference

8 April 2019

SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

negative regulation of cell migration

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

hematopoietic stem cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

trophectodermal cell differentiation

1 reference

8 April 2019

HOP/NECC1, a novel regulator of mouse trophoblast differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

positive thymic T cell selection

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

Androgen induction of the androgen receptor coactivator four and a half LIM domain protein-2: evidence for a role for serum response factor in prostate cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

sarcomere organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

actin cytoskeleton organization

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

megakaryocyte development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

cardiac vascular smooth muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

multicellular organism development

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11831&geneProductId=UniProtKB:P11831

tangential migration from the subventricular zone to the olfactory bulb

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

contractile actin filament bundle assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

bicellular tight junction assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

leukocyte differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

hippocampus development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

positive regulation of transcription by RNA polymerase II

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

HOP/NECC1, a novel regulator of mouse trophoblast differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

8 April 2019

miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

erythrocyte development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

forebrain development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11831

positive regulation of DNA-binding transcription factor activity

PBB GE SRF 202401 s at fs.png
732 × 530; 11 KB

0 references

has part(s)

Transcription factor, MADS-box

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11831

MADS SRF-like

1 reference

stated in

InterPro Release 71.0