RB transcriptional corepressor like 1 (Q907420)

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mammalian protein found in Homo sapiens

• retinoblastoma-like 1
• RBL1
• retinoblastoma-like protein 1
• 107 kDa retinoblastoma-associated protein
• pRb1
• p107

edit

Language	Label	Description	Also known as
English	RB transcriptional corepressor like 1	mammalian protein found in Homo sapiens	retinoblastoma-like 1 RBL1 retinoblastoma-like protein 1 107 kDa retinoblastoma-associated protein pRb1 p107

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P28749

part of

Cyclin-like superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P28749

Retinoblastoma-like protein 1

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P28749

Cyclin-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

Retinoblastoma-associated protein, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Retinoblastoma-associated protein, B-box family

1 reference

based on heuristic

inferred from protein domain or family

Retinoblastoma-associated protein, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Retinoblastoma-associated protein, A-box family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P28749

encoded by

RBL1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P28749

molecular function

transcription factor binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

GOA

curator

UniProt

UniProt protein ID

P28749

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

protein binding

determination method

IPI

14 references

retrieved

8 April 2019

stated in

The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta

GOA

curator

UniProt

UniProt protein ID

P28749

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

Towards a proteome-scale map of the human protein–protein interaction network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

The protein interaction landscape of the human CMGC kinase group

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

Interaction of the pRB-family proteins with factors containing paired-like homeodomains

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

The E7 proteins of low- and high-risk human papillomaviruses share the ability to target the pRB family member p130 for degradation

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

retrieved

8 April 2019

stated in

Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IPI

promoter-specific chromatin binding

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IDA

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method

IBA

2 references

retrieved

10 September 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28749&geneProductId=UniProtKB:P28749

determination method

IBA

retrieved

7 November 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28749&geneProductId=UniProtKB:P28749

determination method

IBA

cell component

nucleus

determination method

IEA

3 references

retrieved

27 February 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P28749

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28749&geneProductId=UniProtKB:P28749

determination method

IEA

retrieved

27 February 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28749&geneProductId=UniProtKB:P28749

determination method

IEA

retrieved

27 February 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28749&geneProductId=UniProtKB:P28749

determination method

IEA

transcription regulator complex

determination method

IEA

2 references

retrieved

27 February 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28749&geneProductId=UniProtKB:P28749

determination method

IEA

retrieved

27 February 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28749&geneProductId=UniProtKB:P28749

determination method

IEA

nucleoplasm

determination method

IDA

TAS

3 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IDA

retrieved

8 April 2019

stated in

Structural and functional characterization of the HPV16 E7 protein expressed in bacteria

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IDA

chromatin

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IBA

nucleus

determination method

IBA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P28749

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IBA

transcription regulator complex

determination method

IBA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IBA

biological process

regulation of cell cycle

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

regulation of transcription by RNA polymerase II

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

cell cycle

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P28749

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

viral process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P28749

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

regulation of transcription, DNA-templated

determination method

IEA

1 reference

retrieved

27 February 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P28749

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28749&geneProductId=UniProtKB:P28749

determination method

IEA

negative regulation of transcription by RNA polymerase II

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

positive regulation of transcription by RNA polymerase II

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

TAS

regulation of lipid kinase activity

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta

GOA

curator

UniProt

UniProt protein ID

P28749

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IDA

negative regulation of gene expression

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IMP

transcription, DNA-templated

determination method

IEA

1 reference

retrieved

27 February 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P28749

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28749&geneProductId=UniProtKB:P28749

determination method

IEA

negative regulation of cellular senescence

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

Deregulation of hsa-miR-20b expression in TNF-α-induced premature senescence of human pulmonary microvascular endothelial cells

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IMP

chromatin organization

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P28749

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

regulation of mitotic cell cycle

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IBA

cell differentiation

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IBA

regulation of cell division

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IEA

negative regulation of G1/S transition of mitotic cell cycle

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28749

determination method

IBA

Gene Atlas image

PBB GE RBL1 205296 at fs.png
732 × 530; 12 KB

0 references

has part(s)

Retinoblastoma-associated protein, N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P28749

Cyclin-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P28749

Retinoblastoma-associated protein, C-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P28749

Retinoblastoma-associated protein, A-box

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P28749

Retinoblastoma-associated protein, B-box

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P28749

Identifiers

MeSH descriptor ID

D050720

subject named as

Retinoblastoma-Like Protein p107

0 references

MeSH tree code

D12.776.624.776.717

0 references

D12.776.660.770

0 references

D12.776.744.747

0 references

RefSeq protein ID

NP_001310210

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5933

NP_001310211

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5933

NP_002886

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5933

NP_899662

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5933

XP_006723905

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5933

XP_016883481

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5933

XP_024307724

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5933

XP_024307725

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5933

XP_024307726

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5933

UniProt protein ID

P28749

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P28749

Ensembl protein ID

ENSP00000343646

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000343646

ENSP00000362768

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000362768

ENSP00000434711

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000434711

ENSP00000437240

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000437240

Freebase ID

/m/03gtjxz

0 references

Microsoft Academic ID

180196505

0 references

OpenAlex ID

C180196505

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1H28

1 reference

stated in

UniProt

UniProt protein ID

P28749

retrieved

30 June 2016

language of work or name

English

4YOO

1 reference

stated in

UniProt

UniProt protein ID

P28749

retrieved

30 June 2016

language of work or name

English

4YOS

1 reference

stated in

UniProt

UniProt protein ID

P28749

retrieved

30 June 2016

language of work or name

English

4YOZ

1 reference

stated in

UniProt

UniProt protein ID

P28749

retrieved

30 June 2016

language of work or name

English

UMLS CUI

C0599575

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(7 entries)

edit

• bswiki Retinoblastom 1
• dewiki Retinoblastoma-like protein 1
• enwiki Retinoblastoma-like protein 1
• eswiki Proteína del retinoblastoma-like 1
• ruwiki RBL1
• ttwiki RBL1
• ukwiki RBL1

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q907420&oldid=2022902964"