Whole-genome sequencing reveals high complexity of copy number variation at insecticide resistance loci in malaria mosquitoes (Q92184424)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31345938%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

title

Whole-genome sequencing reveals high complexity of copy number variation at insecticide resistance loci in malaria mosquitoes (English)

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27 April 2020

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insecticide resistance

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whole genome sequencing

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1

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27 April 2020

Nicholas J Harding

3

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27 April 2020

Dominic P. Kwiatkowski

6

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27 April 2020

David Weetman

7

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27 April 2020

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Mara K N Lawniczak

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27 April 2020

author name string

Alistair Miles

2

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27 April 2020

Chris S Clarkson

4

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27 April 2020

Martin J Donnelly

8

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27 April 2020

Anopheles gambiae 1000 Genomes Consortium

9

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27 April 2020

publication date

25 July 2019

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27 April 2020

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27 April 2020

volume

29

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27 April 2020

issue

8

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27 April 2020

page(s)

1250-1261

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Copy number variation (CNV) and insecticide resistance in mosquitoes: evolving knowledge or an evolving problem?

27 April 2020

cites work

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Rapid selection of a pyrethroid metabolic enzyme CYP9K1 by operational malaria control activities.

23 February 2021

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Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-tw

23 February 2021

1 reference

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Pyrethroid Resistance in the Major Malaria Vector Anopheles funestus is Exacerbated by Overexpression and Overactivity of the P450 CYP6AA1 Across Africa.

23 February 2021

1 reference

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Neofunctionalization of Duplicated P450 Genes Drives the Evolution of Insecticide Resistance in the Brown Planthopper

23 February 2021

1 reference

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Genetic diversity of the African malaria vector Anopheles gambiae

23 February 2021

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Detection and quantitation of copy number variation in the voltage-gated sodium channel gene of the mosquito Culex quinquefasciatus.

23 February 2021

1 reference

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Resistance to malaria through structural variation of red blood cell invasion receptors

23 February 2021

1 reference

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The ace-1 Locus Is Amplified in All Resistant Anopheles gambiae Mosquitoes: Fitness Consequences of Homogeneous and Heterogeneous Duplications

23 February 2021

1 reference

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Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum

23 February 2021

1 reference

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Does insecticide resistance contribute to heterogeneities in malaria transmission in The Gambia?

23 February 2021

1 reference

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Parallel Evolution of Copy-Number Variation across Continents in Drosophila melanogaster

23 February 2021

1 reference

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Identification, Validation, and Application of Molecular Diagnostics for Insecticide Resistance in Malaria Vectors

23 February 2021

1 reference

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Insecticide resistance profile of Anopheles gambiae from a phase II field station in Cové, southern Benin: implications for the evaluation of novel vector control products

23 February 2021

1 reference

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An ace-1 gene duplication resorbs the fitness cost associated with resistance in Anopheles gambiae, the main malaria mosquito

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Complex genome evolution in Anopheles coluzzii associated with increased insecticide usage in Mali

23 February 2021

1 reference

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Global diversity, population stratification, and selection of human copy-number variation

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Identifying genomic changes associated with insecticide resistance in the dengue mosquito Aedes aegypti by deep targeted sequencing

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Repbase Update, a database of repetitive elements in eukaryotic genomes

23 February 2021

1 reference

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Transcriptome Profiling and Genetic Study Reveal Amplified Carboxylesterase Genes Implicated in Temephos Resistance, in the Asian Tiger Mosquito Aedes albopictus

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Contemporary evolution of resistance at the major insecticide target site gene Ace-1 by mutation and copy number variation in the malaria mosquito Anopheles gambiae

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Large multiallelic copy number variations in humans

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Insecticide resistance in mosquitoes: impact, mechanisms, and research directions

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

The highly polymorphic CYP6M7 cytochrome P450 gene partners with the directionally selected CYP6P9a and CYP6P9b genes to expand the pyrethroid resistance front in the malaria vector Anopheles funestus in Africa

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Underpinning sustainable vector control through informed insecticide resistance management

23 February 2021

1 reference

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Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in a major malaria vector

23 February 2021

1 reference

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Evidence for gene duplication in the voltage-gated sodium channel gene of Aedes aegypti

23 February 2021

1 reference

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Gene duplication in the major insecticide target site, Rdl, in Drosophila melanogaster

23 February 2021

1 reference

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Resistance to DDT in an urban setting: common mechanisms implicated in both M and S forms of Anopheles gambiae in the city of Yaoundé Cameroon.

23 February 2021

1 reference

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Dissecting the mechanisms responsible for the multiple insecticide resistance phenotype in Anopheles gambiae s.s., M form, from Vallée du Kou, Burkina Faso

23 February 2021

1 reference

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Genotype calling and phasing using next-generation sequencing reads and a haplotype scaffold

23 February 2021

1 reference

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Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Cis-acting mutation and duplication: History of molecular evolution in a P450 haplotype responsible for insecticide resistance in Culex quinquefasciatus.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Gene amplification and insecticide resistance

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

CNVnator: an approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Characterization of mosquito CYP6P7 and CYP6AA3: differences in substrate preference and kinetic properties

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

The role of the Aedes aegypti Epsilon glutathione transferases in conferring resistance to DDT and pyrethroid insecticides.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Genome mapping and characterization of the Anopheles gambiae heterochromatin

23 February 2021

1 reference

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Copy number variation and transposable elements feature in recent, ongoing adaptation at the Cyp6g1 locus

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Field-caught permethrin-resistant Anopheles gambiae overexpress CYP6P3, a P450 that metabolises pyrethroids

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Transcriptomic and genomic evolution under constant cold in Antarctic notothenioid fish

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Comparative molecular modeling of Anopheles gambiae CYP6Z1, a mosquito P450 capable of metabolizing DDT

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Natural selection shapes genome-wide patterns of copy-number polymorphism in Drosophila melanogaster.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Distribution and functional impact of DNA copy number variation in the rat.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Forty years of erratic insecticide resistance evolution in the mosquito Culex pipiens

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Transcription profiling of a recently colonised pyrethroid resistant Anopheles gambiae strain from Ghana

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Global variation in copy number in the human genome

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Molecular mechanisms of metabolic resistance to synthetic and natural xenobiotics

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Bias of selection on human copy-number variants

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Cytochrome P450 genes: molecular cloning and overexpression in a pyrethroid-resistant strain of Anopheles minimus mosquito

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

The Anopheles gambiae detoxification chip: a highly specific microarray to study metabolic-based insecticide resistance in malaria vectors

23 February 2021

1 reference

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A global index representing the stability of malaria transmission.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

An adult-specific CYP6 P450 gene is overexpressed in a pyrethroid-resistant strain of the malaria vector, Anopheles gambiae

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

The Anopheles gambiae glutathione transferase supergene family: annotation, phylogeny and expression profiles

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Detecting recent positive selection in the human genome from haplotype structure

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Insecticide resistance in the mosquito culex pipiens: what have we learned about adaptation?

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Relationship between amount of esterase and gene copy number in insecticide-resistant Myzus persicae (Sulzer).

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

Excisions of the Ikirara1 transposon in an Anopheles gambiae cell line.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6673711

23 February 2021

Identifiers

DOI

10.1101/GR.245795.118

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31345938%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31345938%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

PubMed publication ID

31345938

1 reference