Talk:Q26939
Autodescription — epigenetics (Q26939)
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We should also have another new topic for alternate meaning of epigenetics:
[edit]which is "functionally relevant changes to the genome that do not involve a change in the nucleotide sequence". The reasoning is so that some historical texts and opinions can be attached to this alternate meaning, which is about the changes themselves, regardless of heritable traits?
The term also refers to the changes themselves: functionally relevant changes to the genome that do not involve a change in the nucleotide sequence.
Historically, some phenomena not necessarily heritable have also been described as epigenetic. For example, the term "epigenetic" has been used to describe any modification of chromosomal regions, especially histone modifications, whether or not these changes are heritable or associated with a phenotype. The consensus definition now requires a trait to be heritable for it to be considered epigenetic
The term epigenetics in its contemporary usage emerged in the 1990s, but for some years has been used with somewhat variable meanings. A consensus definition of the concept of epigenetic trait as a "stably heritable phenotype resulting from changes in a chromosome without alterations in the DNA sequence" was formulated at a Cold Spring Harbor meeting in 2008, although alternate definitions that include non-heritable traits are still being used.
Based on those 3 sentences above that describe this alternate meaning of "regardless of inheritance" from the Wikipedia article, do others agree we should probably have another new topic of "epigenetics" to cover that alternate meaning? --Thadguidry (talk) 23:42, 26 November 2020 (UTC)