Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway. (Q33924453)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11067868%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway (English)

1 reference

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1 November 2019

0 references

3

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1 November 2019

author name string

D E Kang

1

1 reference

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1 November 2019

C U Pietrzik

2

1 reference

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1 November 2019

N Chevallier

4

1 reference

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1 November 2019

D E Merriam

5

1 reference

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1 November 2019

M Z Kounnas

6

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1 November 2019

S L Wagner

7

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1 November 2019

J C Troncoso

8

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1 November 2019

C H Kawas

9

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1 November 2019

R Katzman

10

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1 November 2019

E H Koo

11

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1 November 2019

language of work or name

English

0 references

publication date

1 November 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11067868%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

1 November 2019

published in

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1 November 2019

volume

106

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1 November 2019

issue

9

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1 November 2019

page(s)

1159-1166

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Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

1 November 2019

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Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

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Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

5 July 2018

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5 July 2018

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5 July 2018

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Cell surface APP751 forms complexes with protease nexin 2 ligands and is internalized via the low density lipoprotein receptor-related protein (LRP).

5 July 2018

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Amyloid beta peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin, and calcineurin.

5 July 2018

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Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

5 July 2018

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5 July 2018

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

5 July 2018

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Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

5 July 2018

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Isoform-specific binding of apolipoprotein E to beta-amyloid

5 July 2018

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Genetic deficiency in low density lipoprotein receptor-related protein confers cellular resistance to Pseudomonas exotoxin A. Evidence that this protein is required for uptake and degradation of multiple ligands

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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29 October 2018

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Alpha2-macroglobulin enhances the clearance of endogenous soluble beta-amyloid peptide via low-density lipoprotein receptor-related protein in cortical neurons.

29 October 2018

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Alpha-2 macroglobulin is genetically associated with Alzheimer disease

29 October 2018

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Low density lipoprotein receptor related protein gene exon 3 polymorphism association with Alzheimer's disease in Chinese.

29 October 2018

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Association at LRP gene locus with sporadic late-onset Alzheimer's disease.

29 October 2018

1 reference

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Confirmation of an association between a polymorphism in exon 3 of the low-density lipoprotein receptor-related protein gene and Alzheimer's disease.

29 October 2018

1 reference

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Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

29 October 2018

1 reference

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The apolipoprotein E epsilon 4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant

29 October 2018

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Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

29 October 2018

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Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

29 October 2018

1 reference

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Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11067868

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11067868

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI11013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11067868%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11067868%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference