Ubiquitin protein ligase E3A (Q14878332)

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mammalian protein found in Homo sapiens
  • human papilloma virus E6-associated protein
  • human papillomavirus E6-associated protein
  • oncogenic protein-associated protein E6-AP
  • ubiquitin-protein ligase E3A
  • CTCL tumor antigen se37-2
  • E6AP ubiquitin-protein ligase
  • HECT-type ubiquitin transferase E3A
  • renal carcinoma antigen NY-REN-54
  • UBE3A
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Language Label Description Also known as
English
Ubiquitin protein ligase E3A
mammalian protein found in Homo sapiens
  • human papilloma virus E6-associated protein
  • human papillomavirus E6-associated protein
  • oncogenic protein-associated protein E6-AP
  • ubiquitin-protein ligase E3A
  • CTCL tumor antigen se37-2
  • E6AP ubiquitin-protein ligase
  • HECT-type ubiquitin transferase E3A
  • renal carcinoma antigen NY-REN-54
  • UBE3A

Statements

molecular function
protein binding
determination method
IPI
13 references
retrieved
8 April 2019
stated in
The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor
GOA
curator
UniProt
UniProt protein ID
Q05086
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors
GOA
curator
UniProt
UniProt protein ID
Q05086
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
Degradation of tyrosine phosphatase PTPN3 (PTPH1) by association with oncogenic human papillomavirus E6 proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
Solution Structure Analysis of the HPV16 E6 Oncoprotein Reveals a Self-Association Mechanism Required for E6-Mediated Degradation of p53
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of papillomavirus E6 oncoproteins with a putative calcium-binding protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
Surface plasmon resonance imaging protein arrays for analysis of triple protein interactions of HPV, E6, E6AP, and p53
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
Association of Bovine Papillomavirus Type 1 E6 oncoprotein with the focal adhesion protein paxillin through a conserved protein interaction motif
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
Association of E6AP (UBE3A) with human papillomavirus type 11 E6 protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
Requirement of E6AP and the features of human papillomavirus E6 necessary to support degradation of p53
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
retrieved
8 April 2019
stated in
VCY2 protein interacts with the HECT domain of ubiquitin-protein ligase E3A
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05086
determination method
IPI
cell component
biological process
Gene Atlas image
PBB GE UBE3A 211285 s at fs.png
732 × 530; 12 KB
0 references

Identifiers

RefSeq protein ID
Ensembl protein ID
 
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