The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 (Q24317677)

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27 October 2019

title

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 (English)

1 reference

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Ubiquitin protein ligase E3A

27 October 2019

main subject

1 reference

GOA release 2020-03-11

proteolysis

1 reference

GOA release 2020-03-11

protein ubiquitination

1 reference

1

1 reference

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27 October 2019

Peter Howley

series ordinal

4

1 reference

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27 October 2019

author name string

J M Huibregtse

series ordinal

2

1 reference

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27 October 2019

R D Vierstra

series ordinal

3

1 reference

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27 October 2019

language of work or name

English

0 references

publication date

1 November 1993

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27 October 2019

1 reference

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27 October 2019

volume

75

1 reference

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27 October 2019

page(s)

495-505

1 reference

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27 October 2019

issue

3

1 reference

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The recognition component of the N-end rule pathway

27 October 2019

cites work

1 reference

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7 January 2021

UBC1 encodes a novel member of an essential subfamily of yeast ubiquitin-conjugating enzymes involved in protein degradation.

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Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins

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Transformation by simian virus 40 does not involve the mutational activation of p53 to an oncogenic form

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7 January 2021

Human papillomaviruses in the pathogenesis of anogenital cancer

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Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

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7 January 2021

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

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7 January 2021

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

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7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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7 January 2021

Natural substrates of the ubiquitin proteolytic pathway

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7 January 2021

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

Genetic analysis of the ubiquitin system

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7 January 2021

T antigen is bound to a host protein in SY40-transformed cells

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7 January 2021

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

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7 January 2021

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

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7 January 2021

Cyclin is degraded by the ubiquitin pathway

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7 January 2021

The p53 tumour suppressor gene

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7 January 2021

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

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7 January 2021

Homologs of the essential ubiquitin conjugating enzymes UBC1, 4, and 5 in yeast are encoded by a multigene family in Arabidopsis thaliana.

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7 January 2021

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

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7 January 2021

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

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7 January 2021

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

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7 January 2021

The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme

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7 January 2021

Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytes

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7 January 2021

p53 functions as a cell cycle control protein in osteosarcomas

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7 January 2021

Post-Translational Regulation of the 54K Cellular Tumor Antigen in Normal and Transformed Cells

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7 January 2021

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

1 reference

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7 January 2021

Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins

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7 January 2021

Two Distinct Mechanisms Regulate the Levels of a Cellular Tumor Antigen, p53

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7 January 2021

Intracellular protein degradation in mammalian and bacterial cells: Part 2

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7 January 2021

The ubiquitin system for protein degradation

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7 January 2021

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Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

475734

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8221889%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

475734

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

475734