Perlecan (heparan sulfate proteoglycan 2) (Q14890113)

LDL receptor-like superfamily

1 reference

Immunoglobulin-like domain superfamily

1 reference

Concanavalin A-like lectin/glucanase domain superfamily

1 reference

Immunoglobulin I-set, protein family

1 reference

Laminin G domain, protein family

1 reference

SEA domain, protein family

1 reference

Immunoglobulin subtype, protein family

1 reference

Immunoglobulin V-set domain, protein family

1 reference

Laminin EGF domain, protein family

1 reference

Laminin IV domain, protein family

1 reference

EGF-like calcium-binding domain, protein family

1 reference

Immunoglobulin subtype 2, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

EGF-like domain, protein family

1 reference

Low-density lipoprotein (LDL) receptor class A, conserved site, protein family

1 reference

EGF-like, conserved site, protein family

1 reference

Low-density lipoprotein (LDL) receptor class A repeat, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

1 reference

9 May 2019

protease binding

1 reference

9 May 2019

Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

protein C-terminus binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

ISO

protein binding

3 references

9 May 2019

WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

calcium ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

1 reference

9 May 2019

extracellular matrix structural constituent conferring compression resistance

2 references

1 January 2018

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05793&geneProductId=UniProtKB:Q05793

1 January 2018

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05793&geneProductId=UniProtKB:Q05793

extracellular matrix structural constituent conferring compression resistance

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

RCA

14 February 2019

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

RCA

14 February 2019

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

14 February 2019

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

extracellular matrix structural constituent conferring compression resistance

RCA

cell component

focal adhesion

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05793&geneProductId=UniProtKB:Q05793

ISO

basement membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

11 references

14 February 2019

14 February 2019

Effects of the curly tail genotype on neuroepithelial integrity and cell proliferation during late stages of primary neurulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

14 February 2019

Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

14 February 2019

The collagen type XVIII endostatin domain is co-localized with perlecan in basement membranes in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

14 February 2019

Transcriptome-based systematic identification of extracellular matrix proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

14 February 2019

Perlecan maintains the integrity of cartilage and some basement membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

14 February 2019

The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

14 February 2019

Perlecan, a basement membrane-type heparan sulfate proteoglycan, in the enamel organ: its intraepithelial localization in the stellate reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

14 February 2019

Basement membrane composition in the early mouse embryo day 7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

14 February 2019

Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

14 February 2019

Expression of the heparan sulfate proteoglycan, perlecan, during mouse embryogenesis and perlecan chondrogenic activity in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

Golgi lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

1 reference

9 May 2019

TAS

extracellular exosome

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05793&geneProductId=UniProtKB:Q05793

ISO

extracellular space

1 reference

9 May 2019

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

extracellular matrix

4 references

9 May 2019

WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Perlecan maintains the integrity of cartilage and some basement membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Dystroglycan organizes axon guidance cue localization and axonal pathfinding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

collagen-containing extracellular matrix

3 references

9 May 2019

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

basement membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

12 references

9 May 2019

9 May 2019

Expression of the heparan sulfate proteoglycan, perlecan, during mouse embryogenesis and perlecan chondrogenic activity in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

The collagen type XVIII endostatin domain is co-localized with perlecan in basement membranes in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Perlecan maintains the integrity of cartilage and some basement membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Transcriptome-based systematic identification of extracellular matrix proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Perlecan, a basement membrane-type heparan sulfate proteoglycan, in the enamel organ: its intraepithelial localization in the stellate reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Basement membrane composition in the early mouse embryo day 7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Effects of the curly tail genotype on neuroepithelial integrity and cell proliferation during late stages of primary neurulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

embryonic skeletal system morphogenesis

biological process

1 reference

9 May 2019

Perlecan maintains the integrity of cartilage and some basement membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

cartilage development involved in endochondral bone morphogenesis

1 reference

9 May 2019

Perlecan is essential for cartilage and cephalic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

protein localization

1 reference

9 May 2019

Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

chondrocyte differentiation

1 reference

9 May 2019

Perlecan is essential for cartilage and cephalic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

cardiac muscle tissue development

1 reference

9 May 2019

Perlecan maintains the integrity of cartilage and some basement membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

endochondral ossification

1 reference

9 May 2019

Perlecan maintains the integrity of cartilage and some basement membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

brain development

1 reference

9 May 2019

Perlecan maintains the integrity of cartilage and some basement membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

1 reference

9 May 2019

glycosaminoglycan biosynthetic process

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q05793

1 reference

21 March 2017

receptor-mediated endocytosis

TAS

IGI

extracellular matrix organization

1 reference

9 May 2019

Perlecan maintains the integrity of cartilage and some basement membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

animal organ morphogenesis

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

tissue development

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

cell migration

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

substrate adhesion-dependent cell spreading

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05793

has part(s)

immunoglobulin subtype

1 reference

immunoglobulin subtype 2

1 reference

immunoglobulin V-set domain

1 reference

immunoglobulin-like domain

1 reference

Laminin G domain

1 reference

EGF-like calcium-binding domain

1 reference

low-density lipoprotein (LDL) receptor class A repeat

1 reference

EGF-like, conserved site

1 reference

SEA domain

1 reference

immunoglobulin I-set

1 reference

Laminin IV

1 reference

EGF-like domain

1 reference

Laminin EGF domain

1 reference

Low-density lipoprotein (LDL) receptor class A, conserved site

1 reference