Perlecan maintains the integrity of cartilage and some basement membranes (Q24680954)

GOA release 2020-03-11

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M Costell

1

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E Gustafsson

2

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A Aszódi

3

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M Mörgelin

4

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W Bloch

5

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E Hunziker

6

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K Addicks

7

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R Timpl

8

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R Fässler

Expression of the heparan sulfate proteoglycan, perlecan, during mouse embryogenesis and perlecan chondrogenic activity in vitro

9

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language of work or name

English

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publication date

29 November 1999

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published in

Journal of Cell Biology

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volume

147

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issue

5

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page(s)

1109-22

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cites work

1 reference

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Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo

7 April 2017

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Collagen II is essential for the removal of the notochord and the formation of intervertebral discs

7 April 2017

1 reference

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The C-terminal domain V of perlecan promotes beta1 integrin-mediated cell adhesion, binds heparin, nidogen and fibulin-2 and can be modified by glycosaminoglycans

7 April 2017

1 reference

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Developmental expression of perlecan during murine embryogenesis

7 April 2017

1 reference

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Expression of heparan sulfate proteoglycan (perlecan) in the mouse blastocyst is regulated during normal and delayed implantation

7 April 2017

1 reference

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Disproportionate micromelia (Dmm) in mice caused by a mutation in the C-propeptide coding region of Col2a1

7 April 2017

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Defective neuromuscular synaptogenesis in agrin-deficient mutant mice

7 April 2017

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Consequences of lack of beta 1 integrin gene expression in mice

7 April 2017

1 reference

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Recombinant domain IV of perlecan binds to nidogens, laminin-nidogen complex, fibronectin, fibulin-2 and heparin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain

28 September 2017

1 reference

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The relationship between perlecan and dystroglycan and its implication in the formation of the neuromuscular junction.

28 September 2017

1 reference

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Perlecan binds to the beta-amyloid proteins (A beta) of Alzheimer's disease, accelerates A beta fibril formation, and maintains A beta fibril stability.

28 September 2017

1 reference

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Beta 1 integrin is essential for teratoma growth and angiogenesis

28 September 2017

1 reference

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Supramolecular assembly of basement membranes

28 September 2017

1 reference

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Radial versus tangential migration of neuronal clones in the developing cerebral cortex

28 September 2017

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Proteoglycans of basement membranes

28 September 2017

1 reference

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Mapping of nidogen binding sites for collagen type IV, heparan sulfate proteoglycan, and zinc.

28 September 2017

1 reference

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Isolation of a heparan sulfate-containing proteoglycan from basement membrane.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Antibodies to basement membrane heparan sulfate proteoglycans bind to the laminae rarae of the glomerular basement membrane (GBM) and induce subepithelial GBM thickening

28 September 2017

1 reference

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Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses

28 September 2017

1 reference

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Endothelial cells interact with the core protein of basement membrane perlecan through beta 1 and beta 3 integrins: an adhesion modulated by glycosaminoglycan

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Cardiac specific expression of the green fluorescent protein during early murine embryonic development.

30 May 2018

1 reference

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Mapping of the binding of platelet-derived growth factor to distinct domains of the basement membrane proteins BM-40 and perlecan and distinction from the BM-40 collagen-binding epitope

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Agrin orchestrates synaptic differentiation at the vertebrate neuromuscular junction

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Characterization of recombinant perlecan domain I and its substitution by glycosaminoglycans and oligosaccharides

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Products of the unc-52 gene in Caenorhabditis elegans are homologous to the core protein of the mammalian basement membrane heparan sulfate proteoglycan

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Distribution of basement membrane antigens in cryopreserved early embryonic hearts.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Primary structure of the human heparan sulfate proteoglycan from basement membrane (HSPG2/perlecan). A chimeric molecule with multiple domains homologous to the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Differential expression of proteoglycans on the surface of human melanoma cells characterized by altered experimental metastatic potential

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Embryonic brain enlargement requires cerebrospinal fluid pressure

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Proteoglycan-mediated inhibition of A beta proteolysis. A potential cause of senile plaque accumulation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

FITC-protein A-gold complex for light and electron microscopic immunocytochemistry

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Expression of nidogen and laminin in basement membranes during mouse embryogenesis and in teratocarcinoma cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169352

Deficiency of beta 1 integrins in teratoma interferes with basement membrane assembly and laminin-1 expression

28 November 2018

1 reference

12 December 2020

A role for dystroglycan in basement membrane assembly

1 reference

12 December 2020

Mechanical function of the septating embryonic heart

1 reference

12 December 2020

The pressure of encephalic fluid in chick embryos between the 2nd and 6th day of incubation

1 reference

12 December 2020

The architectural development of the early mammalian heart

1 reference

12 December 2020

Cajal-Retzius cell ontogenesis and death in mouse brain visualized with horseradish peroxidase and electron microscopy

1 reference

12 December 2020

Ultrastructural localization of intracellular antigens by the use of protein A-gold complex

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.147.5.1109

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1083/JCB.147.5.1109

1 reference

1 reference

1 reference

PubMed publication ID

10579729

1 reference